AR038216A1 - Acido nucleico que codifica un receptor acoplado a la proteina g, y sus usos - Google Patents

Acido nucleico que codifica un receptor acoplado a la proteina g, y sus usos

Info

Publication number
AR038216A1
AR038216A1 ARP030100189A ARP030100189A AR038216A1 AR 038216 A1 AR038216 A1 AR 038216A1 AR P030100189 A ARP030100189 A AR P030100189A AR P030100189 A ARP030100189 A AR P030100189A AR 038216 A1 AR038216 A1 AR 038216A1
Authority
AR
Argentina
Prior art keywords
receptor
protein
nucleic acid
receptor coupled
gave6
Prior art date
Application number
ARP030100189A
Other languages
English (en)
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of AR038216A1 publication Critical patent/AR038216A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Se provee en la presente un receptor novedoso y útil acoplado a la proteína G que está involucrado en la transducción de senales con respecto a la inflamación y a la respuesta inmunológica fisiológica. También se proveen métodos para utilizar el receptor en la selección de moléculas que puedan modular la actividad del receptor. Dichas moléculas pueden tener fácilmente aplicaciones en el tratamiento de un sinnúmero de enfermedades y trastornos. También se proveen anticuerpos contra dicho receptor GAVE6, vectores que contienen el ácido nucleico que codifica dicho GAVE6, células huéspedes y un método para producir dicho polipéptido.
ARP030100189A 2002-01-23 2003-01-22 Acido nucleico que codifica un receptor acoplado a la proteina g, y sus usos AR038216A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35100602P 2002-01-23 2002-01-23
GBGB0210597.1A GB0210597D0 (en) 2002-01-23 2002-05-09 A nucleic acid encoding a G-protein-coupled receptor,and uses thereof

Publications (1)

Publication Number Publication Date
AR038216A1 true AR038216A1 (es) 2005-01-05

Family

ID=23379187

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP030100189A AR038216A1 (es) 2002-01-23 2003-01-22 Acido nucleico que codifica un receptor acoplado a la proteina g, y sus usos

Country Status (7)

Country Link
US (1) US20030186873A1 (es)
KR (1) KR20040077791A (es)
CN (1) CN1813187A (es)
AR (1) AR038216A1 (es)
GB (1) GB0210597D0 (es)
TW (1) TW200307688A (es)
ZA (1) ZA200405261B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3204772B2 (en) * 2014-10-10 2023-12-20 Mars, Incorporated Methods for identifying modulators of calcium-sensing receptors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955308A (en) * 1997-06-18 1999-09-21 Smithkline Beecham Corporation cDNA clone HEAOD54 that encodes a human 7-transmembrane receptor
US6140509A (en) * 1998-06-26 2000-10-31 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof
US6150393A (en) * 1998-12-18 2000-11-21 Arena Pharmaceuticals, Inc. Small molecule modulators of non-endogenous, constitutively activated human serotonin receptors

Also Published As

Publication number Publication date
US20030186873A1 (en) 2003-10-02
CN1813187A (zh) 2006-08-02
ZA200405261B (en) 2005-06-17
GB0210597D0 (en) 2002-06-19
TW200307688A (en) 2003-12-16
KR20040077791A (ko) 2004-09-06

Similar Documents

Publication Publication Date Title
ES2161246T3 (es) Factor transformante de crecimiento alfa h1.
BR0313492A (pt) Formulação de anticorpos humanos para tratar distúrbios associados ao tnf-alfa
TW200626173A (en) IL-23p40 specific immunoglobulin derived proteins, compositions, epitopes, methods and uses
NO961115D0 (no) Humane metabotrope glutamatreseptorsubtyper (HMR4, HMR6, HMR7) og relaterte DNA forbindelser
BR0207325A (pt) Métodos terapêuticos para doenças associadas com expressão diminuìda de gene de aop-1 ou aop-1
ATE540575T1 (de) Regulatoren des zucker- und lipidstoffwechsels in pflanzen
MX9206041A (es) Proceso para producir interferon inmune humano.
AR023230A1 (es) Polipeptidos mutantes con actividad de alfa-amilasa alcalina y usos de dichos polipeptidos.
WO2003016486A3 (en) Bio-synthetic photostimulators and methods of use
ATE490984T1 (de) Methode zur produktion und evaluierung der zytotoxizität von kir2dl nk-rezeptor antikörpern
PH12021550001A1 (en) Novel fusion protein specific for cd137 and pd-l1
ATE430198T1 (de) Antikörperkonstruktion unter verwendung einer mrl/lpr-maus
MX9306220A (es) Ptp 1d: una proteina tirosina fosfatasa novedosa.
BR0315327A (pt) Antagonistas de il-15
HUP0002472A2 (hu) Izolált dendritikus sejtmembrán-fehérje gének
DE60137829D1 (de) Menschliche stra6 polypeptide
DE69837475D1 (de) Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren
BR9710975A (pt) Genes de proteìna de adesão de superfìcie exposta de 120 kda imunodominante de ehrlichia chaffeensis
AR038216A1 (es) Acido nucleico que codifica un receptor acoplado a la proteina g, y sus usos
IL150115A (en) Isolated antibody that binds to rg1 polypeptides, immunosuppressant containing this antibody, antibody uses, and methods utilizing it
ATE464320T1 (de) Ntb-a, ein oberflächenmolekül impliziert in der aktivität natürlicher killerzellen (nk)
WO2004005475A3 (en) Purified and isolated heparan sulfate 3-o-sulfotransferase isoform 5 nucleic acids and polypeptides and therapeutic and screening methods using same
NO980122L (no) Emaljematriksrelatert polypeptid
ATE311456T1 (de) Nucleinsäure-moleküle codierend proteine, die die adhäsion von neisseria-zellen an humane zellen vermitteln
ATE473999T1 (de) Polypeptide und nukleinsäuren, die diese codieren

Legal Events

Date Code Title Description
FB Suspension of granting procedure