AR037336A1 - Sistema antimicrobiano que comprende un tensioactivo cationico, composicion cosmetica que lo contiene y uso del mismo - Google Patents
Sistema antimicrobiano que comprende un tensioactivo cationico, composicion cosmetica que lo contiene y uso del mismoInfo
- Publication number
- AR037336A1 AR037336A1 ARP020104281A ARP020104281A AR037336A1 AR 037336 A1 AR037336 A1 AR 037336A1 AR P020104281 A ARP020104281 A AR P020104281A AR P020104281 A ARP020104281 A AR P020104281A AR 037336 A1 AR037336 A1 AR 037336A1
- Authority
- AR
- Argentina
- Prior art keywords
- lae
- antimicrobials
- cationic
- preparations
- activity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Communicable Diseases (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La presente invención se refiere a un uso novedoso de conservadores catiónicos y preparaciones de acuerdo con este uso novedoso. Puede usarse un conservador catiónico derivado de ácido láurico y arginina, en particular el éster etílico de la lauramida del monoclorhidrato de arginina, denominado a continuación LAE, para la protección contra la proliferación de microorganismos. La estructura química de LAE se describe por la siguiente fórmula: LAE y los compuestos relacionados son particularmente adecuados para ser usados para mejorar la actividad de los antimicrobianos tradicionales en desodorantes y en preparaciones para el cuidado bucal. La actividad antimicrobiana de la combinación de LAE y compuestos relacionados con la mayoría de los antimicrobianos comunes en dichas preparaciones es mayor que la actividad exhibida por cada uno de los componentes usados por sí solos. LAE puede ser usado en combinación con antimicrobianos como 2, 4, 4'-tricloro-2'-hidroxi-difeniléter ((triclosan) y/o 3, 4, 4-triclorocarbanilida (triclocarban) y/o 2-fenoxietanol y/o sales de clorohexidina y/o hexetidina y/o sales de cetilpridinio.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2001/013221 WO2003043593A1 (en) | 2001-11-15 | 2001-11-15 | Use of cationic surfactant as antimicrobial activity enhancer in deodorants and oral care |
Publications (1)
Publication Number | Publication Date |
---|---|
AR037336A1 true AR037336A1 (es) | 2004-11-03 |
Family
ID=8164676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP020104281A AR037336A1 (es) | 2001-11-15 | 2002-11-07 | Sistema antimicrobiano que comprende un tensioactivo cationico, composicion cosmetica que lo contiene y uso del mismo |
Country Status (11)
Country | Link |
---|---|
US (1) | US7196117B2 (es) |
EP (2) | EP1443892B1 (es) |
AR (1) | AR037336A1 (es) |
AT (1) | ATE433315T1 (es) |
AU (1) | AU2002218301A1 (es) |
BR (2) | BR0116767A (es) |
CA (1) | CA2467244C (es) |
DE (1) | DE60138971D1 (es) |
ES (2) | ES2427841T3 (es) |
MX (1) | MXPA04004592A (es) |
WO (1) | WO2003043593A1 (es) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA04010976A (es) * | 2002-05-08 | 2005-01-25 | Miret Lab | Nuevos conservadores y sistemas protectores. |
US8795638B1 (en) | 2003-08-26 | 2014-08-05 | Nevada Naturals Inc. | Compositions for dental care |
US8193244B1 (en) | 2008-05-29 | 2012-06-05 | Nevada Naturals, Inc. | Antimicrobial agents |
US20100056628A1 (en) * | 2006-09-07 | 2010-03-04 | Stockel Richard F | Preservative compositions |
US8926997B1 (en) | 2003-02-06 | 2015-01-06 | Richard F. Stockel | Polymeric biocidal salts |
US8287843B2 (en) * | 2003-06-23 | 2012-10-16 | Colgate-Palmolive Company | Antiplaque oral care compositions |
EP1635774B2 (en) * | 2003-06-23 | 2011-01-26 | Colgate-Palmolive Company | Stable dentifrice compositions |
US8425881B2 (en) * | 2005-03-18 | 2013-04-23 | Colgate-Palmolive Company | Antibacterial 3′,5-disubstituted 2,4′-dihydroxybiphenyl compounds, derivatives and related methods |
AU2006227690B2 (en) * | 2005-03-18 | 2009-12-24 | Colgate-Palmolive Company | Antibacterial 5',5-disubstituted 3,3'-dialkoxy-2,2'-dihydroxy- 1,1'-biphenyl compounds and related methods |
US8840876B2 (en) | 2005-05-19 | 2014-09-23 | Ethicon, Inc. | Antimicrobial polymer compositions and the use thereof |
US20060264347A1 (en) * | 2005-05-19 | 2006-11-23 | Xintian Ming | Antimicrobial composition |
US20060263444A1 (en) | 2005-05-19 | 2006-11-23 | Xintian Ming | Antimicrobial composition |
US8604073B2 (en) * | 2006-03-27 | 2013-12-10 | Ethicon, Inc. | Antimicrobial composition |
AU2006346933A1 (en) * | 2006-08-03 | 2008-02-07 | Laboratorios Miret, S.A. | Antiviral use of cationic surfactant |
US7968656B2 (en) | 2006-10-31 | 2011-06-28 | Ethicon, Inc. | Absorbable copolyesters of poly(ethoxyethylene diglycolate) and glycolide |
WO2008095534A1 (en) * | 2007-02-07 | 2008-08-14 | Laboratorios Miret, S.A. | New combination of cationic preservatives with taste-masking components |
EP2184991B1 (en) | 2007-09-13 | 2015-09-02 | Laboratorios Miret, S.A. | Combinations of polyene fungicide with cationic surfactants |
US20090087461A1 (en) * | 2007-10-01 | 2009-04-02 | Thomas James Boyd | Anti-bacterial pyrocatechols and related methods |
PE20091399A1 (es) * | 2008-02-08 | 2009-10-03 | Colgate Palmolive Co | Producto de cuidado bucal y fabricacion del mismo |
US20090226549A1 (en) | 2008-03-06 | 2009-09-10 | Kenneth John Hughes | Herbal extracts and flavor systems for oral products and methods of making the same |
US9023891B2 (en) | 2008-05-29 | 2015-05-05 | Nevada Naturals, Inc. | Synergistic antimicrobial agents |
BRPI0913835A2 (pt) | 2008-07-02 | 2016-08-09 | Miret Lab | uso de tensoativos catiônicos como agentes esporicidas |
AR074274A1 (es) * | 2008-11-21 | 2011-01-05 | Vedeqsa Inc | Uso de tensioactivos cationicos para la inactivacion de toxinas |
WO2010084052A2 (en) | 2009-01-22 | 2010-07-29 | Laboratorios Miret, S. A. | Use of cationic surfactants as acaricidal agents |
DE102009010665A1 (de) | 2009-02-27 | 2010-09-16 | Beiersdorf Ag | Verwendung von geladenen Tensiden zur Verminderung der Textilverfleckung durch Antitranspirantien |
US20100324137A1 (en) * | 2009-06-22 | 2010-12-23 | Diversey, Inc. | Lauric arginate as a contact antimicrobial |
US9200112B2 (en) | 2009-08-10 | 2015-12-01 | Ethicon, Inc. | Semi-crystalline, fast absorbing polymer formulation |
EP2295114A1 (de) * | 2009-09-10 | 2011-03-16 | Dalli-Werke GmbH & Co. KG | Kosmetische Zusammensetzung mit antimikrobieller Wirkung |
US9044524B2 (en) | 2009-10-30 | 2015-06-02 | Ethicon, Inc. | Absorbable polyethylene diglycolate copolymers to reduce microbial adhesion to medical devices and implants |
DE102010002195A1 (de) | 2010-02-22 | 2011-08-25 | Henkel AG & Co. KGaA, 40589 | Mund- und Zahnpflege- und -reinigungsmittel mit Ethyllaurolarginat |
DE102010002194A1 (de) | 2010-02-22 | 2011-08-25 | Henkel AG & Co. KGaA, 40589 | Desensibilisierende Mund- und Zahnpflege- und -reinigungsmittel mit Ethyllauroylarginat |
WO2011119517A2 (en) | 2010-03-23 | 2011-09-29 | Gojo Industries, Inc. | Antimicrobial compositions |
AU2011254206B2 (en) | 2010-05-20 | 2015-06-25 | Ecolab Usa Inc. | Rheology modified low foaming liquid antimicrobial compositions and methods of use thereof |
EP2585025B2 (en) | 2010-06-23 | 2022-10-26 | Colgate-Palmolive Company | Therapeutic oral composition |
EP2409702A1 (en) | 2010-07-21 | 2012-01-25 | Bayer Innovation GmbH | Combination of siloxane and active ingredient for treating dental disorder of hard tissues |
WO2012013577A1 (en) | 2010-07-26 | 2012-02-02 | Laboratorios Miret, S.A. | Composition for coating medical devices containing lae and a polycationic amphoteric polymer |
DE102010038952A1 (de) | 2010-08-05 | 2012-02-09 | Henkel Ag & Co. Kgaa | Konservierungsmittel-Zusammensetzungen und Kosmetika enthaltend diese |
WO2012055855A1 (en) * | 2010-10-29 | 2012-05-03 | Laboratorios Miret, S.A. | Concentrated preparations of lae and their use |
WO2012064557A2 (en) * | 2010-11-08 | 2012-05-18 | Lipo Chemicals Inc. | Deodorizing compositions |
US8834857B1 (en) | 2011-01-18 | 2014-09-16 | Nevada Naturals Inc. | Deodorizing and skin cleaning |
WO2012164061A2 (en) * | 2011-06-03 | 2012-12-06 | Laboratorios Miret, S.A. | Cosmetic preparations against dandruff |
DE102011089407A1 (de) | 2011-12-21 | 2013-06-27 | Henkel Ag & Co. Kgaa | Konservierungsmittelzusammensetzungen und Kosmetika enthaltend diese |
DE102012223401A1 (de) | 2012-12-17 | 2014-06-18 | Henkel Ag & Co. Kgaa | Emulsion mit antibakteriellem Wirkstoff |
BR112015027158A8 (pt) * | 2013-05-02 | 2018-08-14 | Next Science Llc | Composição antimicrobiana de alta osmolaridade contendo um ou mais solventes orgânicos |
US20150053211A1 (en) * | 2013-08-26 | 2015-02-26 | Richard F. Stockel | Cleaning and safe mouth guard solution |
DE102013226874A1 (de) | 2013-12-20 | 2014-04-17 | Henkel Ag & Co. Kgaa | Konservierungsmittel für Kosmetika |
AU2016321383B2 (en) * | 2015-09-11 | 2021-12-23 | Wm. Wrigley Jr. Company | Synergistic antibacterial effects of magnolia bark extract and L-arginine, N-alpha-lauroyl ethyl ester on salivary bacteria |
DE102015223821A1 (de) * | 2015-12-01 | 2017-06-01 | Henkel Ag & Co. Kgaa | "Leistungsstarke Haarbehandlungsmittel mit strukturstärkendem-Effekt" |
DE102015225006A1 (de) | 2015-12-11 | 2017-06-14 | Henkel Ag & Co. Kgaa | Tensid-haltige Reinigungsmittel mit speziellen Konservierungsmittelkombinationen |
DE102015225003A1 (de) | 2015-12-11 | 2017-06-14 | Henkel Ag & Co. Kgaa | Emulsionen enthaltend mindestens drei voneinander verschiedene Konservierungsmittel |
DE102015225004A1 (de) | 2015-12-11 | 2017-06-14 | Henkel Ag & Co. Kgaa | Tensid-haltige Reinigungsmittel mit mindestens drei unterschiedlichen Konservierungsmitteln |
DE102015225005A1 (de) | 2015-12-11 | 2017-06-14 | Henkel Ag & Co. Kgaa | Emulsionen enthaltend mindestens eine spezielle Konservierungsmittelkombination |
DE102015225687A1 (de) | 2015-12-17 | 2017-06-22 | Henkel Ag & Co. Kgaa | Treibmittelfreie Deodorant- und/oder Antitranspirantien mit mindestens zwei voneinander verschiedenen Konservierungsmitteln |
DE102015225686A1 (de) | 2015-12-17 | 2017-06-22 | Henkel Ag & Co. Kgaa | Treibmittel-haltige Deodorant- und/oder Antitranspirantien mit mindestens zwei voneinander verschiedenen Konservierungsmitteln |
DE102015225693A1 (de) | 2015-12-17 | 2017-06-22 | Henkel Ag & Co. Kgaa | Treibmittelfreie Deodorant- und/oder Antitranspirantien mit speziellen Konservierungsmittelkombinationen |
DE102015225694A1 (de) | 2015-12-17 | 2017-06-22 | Henkel Ag & Co. Kgaa | Treibmittelhaltige Deodorant- und/oder Antitranspirantien mit speziellen Konservierungsmittelkombinationen |
US11331253B2 (en) * | 2019-11-14 | 2022-05-17 | Colgate-Palmolive Company | Personal care compositions for treating odor causing bacteria and methods for the same |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2143557A1 (en) * | 1971-06-29 | 1973-02-09 | Ajinomoto Kk | Antimicrobial n-acyl basic amino acid derivs - useful as antiseptics, preservatives, disinfectants etc |
FR2330399A1 (fr) * | 1975-11-06 | 1977-06-03 | Dolorgiet Arzneimittelfabrik | Nouveaux sels de 1,3-bis-(b-ethylhexyl)-5-amino-5-methyl-hexadydropyrimidine, leur procede de preparation, et leur utilisation therapeutique |
JPH0684294B2 (ja) * | 1990-05-29 | 1994-10-26 | サンスター株式会社 | 口腔用組成物 |
GB9224598D0 (en) * | 1992-11-24 | 1993-01-13 | Smithkline Beecham Plc | Novel compositions |
AU6240294A (en) * | 1993-02-26 | 1994-09-14 | Wesley-Jessen Corporation | Method and composition for disinfecting contact lenses |
ES2092958B1 (es) * | 1995-01-10 | 1997-08-01 | Miret Lab | Procedimiento para la sintesis de tensioactivos cationicos derivados de la condensacion de acidos grasos con aminoacidos de caracter basico esterificados y su aplicacion como agentes antimicrobianos. |
JP3922594B2 (ja) * | 1996-03-19 | 2007-05-30 | 株式会社ノエビア | 抗菌性低刺激化粧料 |
JP3568077B2 (ja) * | 1996-08-02 | 2004-09-22 | 株式会社ノエビア | 抗菌性低刺激化粧料 |
-
2001
- 2001-11-15 AT AT01274736T patent/ATE433315T1/de active
- 2001-11-15 WO PCT/EP2001/013221 patent/WO2003043593A1/en not_active Application Discontinuation
- 2001-11-15 ES ES09150602T patent/ES2427841T3/es not_active Expired - Lifetime
- 2001-11-15 EP EP01274736A patent/EP1443892B1/en not_active Expired - Lifetime
- 2001-11-15 BR BR0116767-7A patent/BR0116767A/pt active IP Right Grant
- 2001-11-15 BR BRPI0116767-7A patent/BRPI0116767B1/pt unknown
- 2001-11-15 EP EP09150602.2A patent/EP2082724B1/en not_active Expired - Lifetime
- 2001-11-15 MX MXPA04004592A patent/MXPA04004592A/es active IP Right Grant
- 2001-11-15 CA CA2467244A patent/CA2467244C/en not_active Expired - Lifetime
- 2001-11-15 DE DE60138971T patent/DE60138971D1/de not_active Expired - Lifetime
- 2001-11-15 ES ES01274736T patent/ES2344002T3/es not_active Expired - Lifetime
- 2001-11-15 AU AU2002218301A patent/AU2002218301A1/en not_active Abandoned
- 2001-11-25 US US10/494,926 patent/US7196117B2/en not_active Expired - Lifetime
-
2002
- 2002-11-07 AR ARP020104281A patent/AR037336A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
DE60138971D1 (de) | 2009-07-23 |
ATE433315T1 (de) | 2009-06-15 |
EP1443892B1 (en) | 2009-06-10 |
EP2082724B1 (en) | 2013-08-21 |
US7196117B2 (en) | 2007-03-27 |
EP1443892A1 (en) | 2004-08-11 |
US20040254232A1 (en) | 2004-12-16 |
AU2002218301A1 (en) | 2003-06-10 |
ES2344002T3 (es) | 2010-08-16 |
BR0116767A (pt) | 2003-12-23 |
MXPA04004592A (es) | 2005-06-08 |
BRPI0116767B1 (pt) | 2019-05-07 |
WO2003043593A1 (en) | 2003-05-30 |
EP2082724A1 (en) | 2009-07-29 |
ES2427841T3 (es) | 2013-11-04 |
CA2467244C (en) | 2011-01-04 |
CA2467244A1 (en) | 2003-05-30 |
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