AR037214A1 - Secuencias de proteinas nucleares de hcv - Google Patents
Secuencias de proteinas nucleares de hcvInfo
- Publication number
- AR037214A1 AR037214A1 ARP020104218A ARP020104218A AR037214A1 AR 037214 A1 AR037214 A1 AR 037214A1 AR P020104218 A ARP020104218 A AR P020104218A AR P020104218 A ARP020104218 A AR P020104218A AR 037214 A1 AR037214 A1 AR 037214A1
- Authority
- AR
- Argentina
- Prior art keywords
- hcv
- modified
- protein
- antibodies
- nuclear
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/20—Analysis of motion
- G06T7/246—Analysis of motion using feature-based methods, e.g. the tracking of corners or segments
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/20—Analysis of motion
- G06T7/277—Analysis of motion involving stochastic approaches, e.g. using Kalman filters
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Theoretical Computer Science (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Multimedia (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente describe péptidos y proteínas recombinantes que contienen la secuencia de la proteína nuclear del virus Hepatitis C en la cual uno o más aminoácidos han sido modificados o suprimidos para eliminar la capacidad de estas proteínas para unirse a anticuerpos monoclonales murinos anti-HCV específicos. Las deleciones y modificaciones han sido disenadas a fin de mantener la aptitud de esta proteína para ser utilizada en los inmunoensayos utilizados para la detección de anticuerpos anti-HCV en individuos infectados por HCV. Reivindicación 1: Un kit para la detección del HCV que comprende A) una fase sólida revestida con proteína nuclear modificada de HCV, proteína no nuclear del HCV y por lo menos un anticuerpo monoclonal antinuclear de HCV y B) un anticuerpo monoclonal antinuclear de HCV conjugado, donde la proteína nuclear modificada de la parte A) ha sido modificada mediante la eliminación de los sitios de unión de los anticuerpos monoclonales antinucleares de la parte A) y la parte B).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34730301P | 2001-11-11 | 2001-11-11 | |
| US10/268,569 US7332269B2 (en) | 2001-11-11 | 2002-10-10 | HCV core protein sequences |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR037214A1 true AR037214A1 (es) | 2004-10-27 |
Family
ID=27668510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020104218A AR037214A1 (es) | 2001-11-11 | 2002-11-05 | Secuencias de proteinas nucleares de hcv |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7332269B2 (es) |
| EP (1) | EP1310512B1 (es) |
| JP (1) | JP4283527B2 (es) |
| AR (1) | AR037214A1 (es) |
| AT (1) | ATE512977T1 (es) |
| BR (1) | BRPI0204599B8 (es) |
| CA (1) | CA2408174C (es) |
| ES (1) | ES2365800T3 (es) |
| PT (1) | PT1310512E (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101287989B (zh) * | 2005-02-02 | 2016-04-13 | 菲鹏生物股份有限公司 | 一种丙型肝炎病毒抗体检测试剂盒及其制备方法 |
| US8865398B2 (en) * | 2006-09-01 | 2014-10-21 | Abbott Laboratories | Combination hepatitis C virus antigen and antibody detection method |
| FR2984328B1 (fr) | 2011-12-20 | 2016-12-30 | Bio-Rad Innovations | Procede de detection d'une infection par le virus de l'hepatite c |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1148859A (en) | 1979-06-14 | 1983-06-28 | Lacy R. Overby | Simultaneous assay of two hepatitis viruses using a solid phase |
| US5683864A (en) * | 1987-11-18 | 1997-11-04 | Chiron Corporation | Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
| US6312889B1 (en) | 1990-04-04 | 2001-11-06 | Chiron Corporation | Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies |
| DE4112743C2 (de) | 1991-04-19 | 2000-01-13 | Dade Behring Marburg Gmbh | Synthetische Core-Peptide zur Bestimmung von HCV-Antikörpern und HCV-Antigenen, Mittel dazu und ihre Verwendung in diesen Nachweis-Verfahren |
| JP3516681B2 (ja) | 1991-06-24 | 2004-04-05 | カイロン コーポレイション | Ｃ型肝炎ウイルス（ｈｃｖ）ポリペプチド |
| DE69837703T2 (de) | 1997-08-04 | 2008-01-10 | Advanced Life Science Institute, Inc., Iruma | Methoden zum nachweis und zur analyse von virus |
| BR9906660A (pt) * | 1998-07-30 | 2000-08-29 | Advanced Life Science Inst Inc | Processo para medir vìrus da hepatite c |
| US6632601B2 (en) | 2000-06-15 | 2003-10-14 | Chiron Corporation | Immunoassays for anti-HCV antibodies |
| AU785380B2 (en) | 2001-03-28 | 2007-03-15 | Ortho-Clinical Diagnostics, Inc. | A hepatitis C antigen - antibody combination assay for the early detection of HCV infection |
| US7101683B2 (en) * | 2001-06-26 | 2006-09-05 | Abbott Laboratories | Methods for the simultaneous detection of HCV antigens and HCV antibodies |
| US20030108563A1 (en) | 2001-11-07 | 2003-06-12 | Chander Bahl | Reagents for the simultaneous detection of HCV core antigens and antibodies |
-
2002
- 2002-10-10 US US10/268,569 patent/US7332269B2/en not_active Expired - Lifetime
- 2002-11-05 AR ARP020104218A patent/AR037214A1/es not_active Application Discontinuation
- 2002-11-05 ES ES02257656T patent/ES2365800T3/es not_active Expired - Lifetime
- 2002-11-05 EP EP02257656A patent/EP1310512B1/en not_active Expired - Lifetime
- 2002-11-05 AT AT02257656T patent/ATE512977T1/de not_active IP Right Cessation
- 2002-11-05 BR BRPI0204599A patent/BRPI0204599B8/pt not_active IP Right Cessation
- 2002-11-05 JP JP2002321298A patent/JP4283527B2/ja not_active Expired - Fee Related
- 2002-11-05 PT PT02257656T patent/PT1310512E/pt unknown
- 2002-11-06 CA CA2408174A patent/CA2408174C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1310512A3 (en) | 2004-01-21 |
| ATE512977T1 (de) | 2011-07-15 |
| EP1310512B1 (en) | 2011-06-15 |
| CA2408174A1 (en) | 2003-05-11 |
| BRPI0204599B8 (pt) | 2021-07-27 |
| JP2003279579A (ja) | 2003-10-02 |
| US20030152965A1 (en) | 2003-08-14 |
| US7332269B2 (en) | 2008-02-19 |
| CA2408174C (en) | 2012-07-17 |
| ES2365800T3 (es) | 2011-10-11 |
| BRPI0204599B1 (pt) | 2018-03-06 |
| PT1310512E (pt) | 2011-08-04 |
| EP1310512A2 (en) | 2003-05-14 |
| BR0204599A (pt) | 2003-09-16 |
| JP4283527B2 (ja) | 2009-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed, e.g., due to non-payment of fee |