ES2163964A1 - Peptidos derivados del extremo amino de la vp5 de orbivirus y su empleo en diagnostico y vacunas. - Google Patents
Peptidos derivados del extremo amino de la vp5 de orbivirus y su empleo en diagnostico y vacunas.Info
- Publication number
- ES2163964A1 ES2163964A1 ES009900360A ES9900360A ES2163964A1 ES 2163964 A1 ES2163964 A1 ES 2163964A1 ES 009900360 A ES009900360 A ES 009900360A ES 9900360 A ES9900360 A ES 9900360A ES 2163964 A1 ES2163964 A1 ES 2163964A1
- Authority
- ES
- Spain
- Prior art keywords
- orbivirus
- vaccines
- peptides
- diagnosis
- peptides derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Peptidos derivados del extremo amino de la VP5 de orbivirus y su empleo en diagnóstico y vacunas. Los péptidos contienen secuencias de 6 a 20 aminoácidos contiguos contenidos en la región comprendida entre los restos de los aminoácidos 70 a 95 de la VP5 de un orbivirus, en particular del VPEA-4. Dicha región contiene varios sitios antigénicos y al menos un determinante antigénico reconocido específicamente por un anticuerpo monoclonal frente a dicho determinante antigénico. Dichos péptidos y anticuerpo monoclonal pueden ser utilizados como reactivos de diagnóstico para orbivirus, particularmente mediante un inmunoensayo basado en un ELISA de bloqueo. Estos péptidos también inducen la producción de anticuerpos neutralizantes del virus y pueden utilizarse en la formulación de vacunas.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009900360A ES2163964B1 (es) | 1999-02-22 | 1999-02-22 | Peptidos derivados del extremo amino de la vp5 de orbivirus y su empleo en diagnostico y vacunas. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009900360A ES2163964B1 (es) | 1999-02-22 | 1999-02-22 | Peptidos derivados del extremo amino de la vp5 de orbivirus y su empleo en diagnostico y vacunas. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2163964A1 true ES2163964A1 (es) | 2002-02-01 |
ES2163964B1 ES2163964B1 (es) | 2003-04-01 |
Family
ID=8307411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES009900360A Expired - Fee Related ES2163964B1 (es) | 1999-02-22 | 1999-02-22 | Peptidos derivados del extremo amino de la vp5 de orbivirus y su empleo en diagnostico y vacunas. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2163964B1 (es) |
-
1999
- 1999-02-22 ES ES009900360A patent/ES2163964B1/es not_active Expired - Fee Related
Non-Patent Citations (3)
Title |
---|
SAKAMOTO et al., "The complete sequences of african horsesickness virus serotype 4 (vaccine strain) RNA segment 2 and 6 which encode outer capsid protein". 1994. J. Vet. Med. Sci. Vol. 56 (2), paginas 321-7. * |
WANG et al., "Use of a gene-targeted phage display random epitope library to map an antigenic determinant of the bluetongue virus outer capsid protein UP5". 1995. J. Immunol. Methods. Vol. 178 (1), paginas 1-12. * |
YANG et al., "Epitopic mapping of linear and conformation-dependent antigenic determinants on GP5 of five U.S. bluetongue viruses". 1992. Virology. Vol. 188 (2), paginas 530-6. * |
Also Published As
Publication number | Publication date |
---|---|
ES2163964B1 (es) | 2003-04-01 |
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