WO1993017108A3 - Peptides analogues de l'image interne d'une proteine virale - Google Patents

Peptides analogues de l'image interne d'une proteine virale Download PDF

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Publication number
WO1993017108A3
WO1993017108A3 PCT/FR1993/000171 FR9300171W WO9317108A3 WO 1993017108 A3 WO1993017108 A3 WO 1993017108A3 FR 9300171 W FR9300171 W FR 9300171W WO 9317108 A3 WO9317108 A3 WO 9317108A3
Authority
WO
WIPO (PCT)
Prior art keywords
sequence
viral protein
internal image
target antigen
analogous peptides
Prior art date
Application number
PCT/FR1993/000171
Other languages
English (en)
Other versions
WO1993017108A2 (fr
Inventor
Velibor Krsmanovic
Irena Cosic
Jean-Michel Biquard
Milton T W Hearn
Original Assignee
Centre Nat Rech Scient
Univ Monash
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Univ Monash filed Critical Centre Nat Rech Scient
Priority to US08/290,736 priority Critical patent/US6294174B1/en
Priority to JP5514589A priority patent/JPH07504409A/ja
Priority to EP93905412A priority patent/EP0728203A1/fr
Priority to DE0728203T priority patent/DE728203T1/de
Priority to AU36361/93A priority patent/AU682304B2/en
Publication of WO1993017108A2 publication Critical patent/WO1993017108A2/fr
Publication of WO1993017108A3 publication Critical patent/WO1993017108A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des peptides immunologiquement apparentés aux protéines exprimées par un agent viral, ayant une séquence d'acides aminés ordonnée à l'aide de la méthode d'analyse informationnelle des protéines à l'aide de la méthode de transformation de Fourier par référence à la séquence d'acides aminés d'un antigène cible contre lequel on souhaite former des anticorps, ou diriger les lymphocytes, cette séquence présentant dans le spectre de Fourier, une ou plusieurs fréquences sensiblement de même valeur que la ou les fréquences caractéristiques de l'antigène cible. Application de ces peptides pour le diagnostic de pathologies virales chez l'homme ou l'animal ou comme compositions immunogènes.
PCT/FR1993/000171 1992-02-19 1993-02-19 Peptides analogues de l'image interne d'une proteine virale WO1993017108A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US08/290,736 US6294174B1 (en) 1992-02-19 1993-02-19 Peptides immunologically related to known viral protein
JP5514589A JPH07504409A (ja) 1992-02-19 1993-02-19 ウィルス因子のタンパク質に免疫学的に近縁するペプチド及びその生物学的利用
EP93905412A EP0728203A1 (fr) 1992-02-19 1993-02-19 Peptides analogues de l'image interne d'une proteine virale
DE0728203T DE728203T1 (de) 1992-02-19 1993-02-19 Zu innerem bild eines virenprotein ahnliche peptide
AU36361/93A AU682304B2 (en) 1992-02-19 1993-02-19 Analogous peptides of the internal image of a viral protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR92/01883 1992-02-19
FR9201883A FR2687404B1 (fr) 1992-02-19 1992-02-19 Peptides immunologiquement apparentes aux proteines d'un agent viral et leurs applications biologiques.

Publications (2)

Publication Number Publication Date
WO1993017108A2 WO1993017108A2 (fr) 1993-09-02
WO1993017108A3 true WO1993017108A3 (fr) 1993-09-16

Family

ID=9426799

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1993/000171 WO1993017108A2 (fr) 1992-02-19 1993-02-19 Peptides analogues de l'image interne d'une proteine virale

Country Status (8)

Country Link
US (1) US6294174B1 (fr)
EP (1) EP0728203A1 (fr)
JP (1) JPH07504409A (fr)
AU (1) AU682304B2 (fr)
CA (1) CA2129827A1 (fr)
DE (1) DE728203T1 (fr)
FR (1) FR2687404B1 (fr)
WO (1) WO1993017108A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0808846A3 (fr) * 1996-05-22 1998-08-26 Diapharm Limited Peptides réactifs avec des anticorps servant de révélateurs de maladie liée au VIH
GB2318352A (en) * 1996-06-25 1998-04-22 Dejan Markovic Polypeptides mimicking the activity of human erythropoietin
KR100608524B1 (ko) * 1997-06-18 2006-08-11 지알 인텔렉츄얼 리저브, 엘엘씨 스펙트럼 촉매
US8262868B2 (en) * 2001-09-11 2012-09-11 Gr Intellectual Reserve, Llc Spectral chemistry
CN112048466A (zh) 2012-04-24 2020-12-08 细胞疗法有限责任公司 从头生成多能细胞
CA2943164C (fr) * 2014-03-19 2024-03-19 Vcell Therapeutics, Inc. Procedes se rapportant a des cellules pluripotentes
US11839650B2 (en) * 2017-02-02 2023-12-12 Board Of Regents, The University Of Texas System Universal influenza vaccine targeting virus/host recognition
EP4333867A1 (fr) 2021-05-03 2024-03-13 QuantBioRes A/S Peptides inhibant la covid-19

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004543A1 (fr) * 1989-09-18 1991-04-04 Nils Tore Brinck Infographie appliquee a la conception moleculaire
EP0431189A1 (fr) * 1989-06-30 1991-06-12 Hitachi, Ltd. Procede et appareil de conception assistee de materiau

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0431189A1 (fr) * 1989-06-30 1991-06-12 Hitachi, Ltd. Procede et appareil de conception assistee de materiau
WO1991004543A1 (fr) * 1989-09-18 1991-04-04 Nils Tore Brinck Infographie appliquee a la conception moleculaire

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIOCHIMIE vol. 71, no. 3, 1989, PARIS, FRANCE pages 333 - 342 COSIC, I. ET AL. 'Prediction of ' *
BIOPOLYMERS vol. 31, no. 7, June 1991, pages 827 - 834 BARBUCCI, R. ET AL. 'Antigen-antibody recognition by Fourier transform IR spectroscopy / Attenuated total reflection studies: biotin-avidin complex as an example' *
EUROPEAN JOURNAL OF BIOCHEMISTRY vol. 198, no. 1, 2 May 1991, pages 113 - 119 COSIC, I. ET AL. 'Resonant recognition model and protein topography : Model studies with myoglobin, hemoglobin and lysozyme' cited in the application *

Also Published As

Publication number Publication date
DE728203T1 (de) 1997-06-05
JPH07504409A (ja) 1995-05-18
FR2687404A1 (fr) 1993-08-20
AU3636193A (en) 1993-09-13
EP0728203A1 (fr) 1996-08-28
AU682304B2 (en) 1997-10-02
WO1993017108A2 (fr) 1993-09-02
CA2129827A1 (fr) 1993-09-02
US6294174B1 (en) 2001-09-25
FR2687404B1 (fr) 1994-05-20

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