AR034432A1 - Perlas recubiertas con aminoglicosido para ensayo de proximidad de centelleo. - Google Patents

Perlas recubiertas con aminoglicosido para ensayo de proximidad de centelleo.

Info

Publication number
AR034432A1
AR034432A1 ARP020102148A ARP020102148A AR034432A1 AR 034432 A1 AR034432 A1 AR 034432A1 AR P020102148 A ARP020102148 A AR P020102148A AR P020102148 A ARP020102148 A AR P020102148A AR 034432 A1 AR034432 A1 AR 034432A1
Authority
AR
Argentina
Prior art keywords
aminoglycoside
centelleo
proximity testing
abm
enzymes
Prior art date
Application number
ARP020102148A
Other languages
English (en)
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of AR034432A1 publication Critical patent/AR034432A1/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)

Abstract

Describe los métodos, ensayos y equipos novedosos para identificar y/o cuantificar moléculas de unión de aminoglicósidos (ABM), enzimas que modifican dichas moléculas, y compuestos que inhiben la interacción entre ABM y enzimas o aminoglicósidos, mediante la explotación del efecto de proximidad de centelleo. La invención que utiliza los soportes de centelleo recubiertos con aminoglicósido, puede adaptarse a formatos de selección de alto rendimiento.
ARP020102148A 2001-06-11 2002-06-07 Perlas recubiertas con aminoglicosido para ensayo de proximidad de centelleo. AR034432A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01113518 2001-06-11

Publications (1)

Publication Number Publication Date
AR034432A1 true AR034432A1 (es) 2004-02-25

Family

ID=8177635

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020102148A AR034432A1 (es) 2001-06-11 2002-06-07 Perlas recubiertas con aminoglicosido para ensayo de proximidad de centelleo.

Country Status (20)

Country Link
US (1) US7157239B2 (es)
EP (1) EP1395677B1 (es)
JP (1) JP4381801B2 (es)
KR (1) KR20040004704A (es)
CN (1) CN1539021A (es)
AR (1) AR034432A1 (es)
AT (1) ATE321878T1 (es)
AU (1) AU2002345801B2 (es)
BG (1) BG108513A (es)
BR (1) BR0210336A (es)
CA (1) CA2448000C (es)
CZ (1) CZ200448A3 (es)
DE (1) DE60210318T2 (es)
EA (1) EA005092B1 (es)
EE (1) EE200400002A (es)
HU (1) HUP0400130A2 (es)
IL (2) IL159227A0 (es)
MX (1) MXPA03011376A (es)
SK (1) SK142004A3 (es)
WO (1) WO2002101084A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253656A1 (en) * 2003-06-11 2004-12-16 David Williams Method for measuring inositol triphosphate
NL1026678C2 (nl) * 2004-07-19 2006-01-23 Tno Werkwijze voor het detecteren en meten van een ligand.
CN101101292B (zh) * 2007-05-11 2011-05-18 中国人民解放军第三军医大学第一附属医院 一种生物分子高通量定量检测方法
EP2239582A1 (en) 2009-04-09 2010-10-13 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Assay system for determining binding to hydrophobic drugs
JP5419012B2 (ja) * 2010-01-12 2014-02-19 独立行政法人理化学研究所 プローブが固定された基体の製造方法及び製造装置
WO2011153464A2 (en) * 2010-06-03 2011-12-08 New York University In situ oriented immobilization of proteins on a support

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271139A (en) 1978-03-27 1981-06-02 Hiram Hart Scintillation proximity assay
EP0154734B1 (en) 1984-03-15 1990-08-29 Immunex Corporation Immediate ligand detection assay, a test kit and its formation
JPS6176418A (ja) 1984-09-23 1986-04-18 Funayama Seizo 発熱性リポ多糖体用吸着剤
IL93205A0 (en) 1989-01-30 1990-11-05 Us Agriculture Column for the separation of macromolecules
JP3505195B2 (ja) 1992-07-09 2004-03-08 バイエルクロップサイエンス株式会社 テトラゾリノン類の水田用除草剤としての利用
US5593835A (en) 1995-05-12 1997-01-14 President And Fellows Of Harvard College Methods and kits for RNA binding compounds
US5945319A (en) * 1996-04-25 1999-08-31 Medtronic, Inc. Periodate oxidative method for attachment of biomolecules to medical device surfaces
US5874273A (en) 1996-06-27 1999-02-23 Onyx Pharmaceuticals G-beta-gamma regulated phosphatidylinositol-3' kinase
CN1285001A (zh) * 1997-12-18 2001-02-21 塞普拉科有限公司 同时鉴定新型生物靶和用于药物开发的引导结构的方法
US5972595A (en) 1997-12-19 1999-10-26 Nen Life Science Products, Inc. Enzyme assay using a solid phase substrate
US5955575A (en) * 1997-12-22 1999-09-21 Hopital Sainte-Justine Antagonists of G-protein-coupled receptor
WO2000000584A2 (en) * 1998-06-26 2000-01-06 University Of Utah Research Foundation Immobilized reagents for kinase assays
CA2345532A1 (en) 1998-09-30 2000-04-06 Joseph Shope Delivery of phosphoinositide polyphosphates into cells
US20040048310A1 (en) * 2001-01-25 2004-03-11 Plowman Gregory D. Novel human protein kinases and protein kinase-like enzymes
GB2366370B (en) * 2000-08-25 2004-11-24 Amersham Pharm Biotech Uk Ltd Reagent for scintillation proximity assays

Also Published As

Publication number Publication date
CA2448000A1 (en) 2002-12-19
EE200400002A (et) 2004-02-16
CA2448000C (en) 2009-12-08
SK142004A3 (en) 2004-06-08
KR20040004704A (ko) 2004-01-13
MXPA03011376A (es) 2004-04-05
EA200400024A1 (ru) 2004-04-29
WO2002101084A3 (en) 2003-02-20
IL159227A0 (en) 2004-06-01
ATE321878T1 (de) 2006-04-15
IL159227A (en) 2009-05-04
AU2002345801B2 (en) 2006-10-26
EP1395677B1 (en) 2006-03-29
EP1395677A2 (en) 2004-03-10
BR0210336A (pt) 2004-07-20
BG108513A (en) 2004-09-30
JP2004533832A (ja) 2004-11-11
US7157239B2 (en) 2007-01-02
DE60210318T2 (de) 2006-08-24
WO2002101084A2 (en) 2002-12-19
JP4381801B2 (ja) 2009-12-09
DE60210318D1 (de) 2006-05-18
EA005092B1 (ru) 2004-10-28
CZ200448A3 (cs) 2004-06-16
CN1539021A (zh) 2004-10-20
HUP0400130A2 (en) 2004-07-28
US20040219693A1 (en) 2004-11-04

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