AR030426A1 - Proteinas sinteticas de tela de arana y su expresion en plantas transgenicas - Google Patents
Proteinas sinteticas de tela de arana y su expresion en plantas transgenicasInfo
- Publication number
- AR030426A1 AR030426A1 ARP010102752A ARP010102752A AR030426A1 AR 030426 A1 AR030426 A1 AR 030426A1 AR P010102752 A ARP010102752 A AR P010102752A AR P010102752 A ARP010102752 A AR P010102752A AR 030426 A1 AR030426 A1 AR 030426A1
- Authority
- AR
- Argentina
- Prior art keywords
- arana
- cloth
- protein
- synthetic
- proteins
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 11
- 108090000623 proteins and genes Proteins 0.000 title abstract 11
- 241000196324 Embryophyta Species 0.000 title abstract 6
- 230000009261 transgenic effect Effects 0.000 title abstract 3
- 239000004744 fabric Substances 0.000 abstract 10
- 241000221016 Schoepfia arenaria Species 0.000 abstract 9
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 241000239290 Araneae Species 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 235000013311 vegetables Nutrition 0.000 abstract 2
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 210000004748 cultured cell Anatomy 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43586—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from silkworms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Insects & Arthropods (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Abstract
El invento se refiere a una secuencia de ADN que codifica una proteína de tela de arana sintética, a las proteínas de tela de arana recombinantes que son codificadas por dicha secuencia de ADN, a los métodos para obtener plantas o células vegetales que contienen proteína de tela de arana recombinante, así como a las células vegetales y las plantas transgénicas que contienen una secuencia de ADN que codifica una proteína de tela de arana sintética. También se refiere a un método para obtener una proteína de tela de arana vegetal a partir de plantas transgénicas, así como a las proteínas de tela de arana vegetales que se obtienen con un método de este tipo. De esta manera se logra poner a disposicion secuencias de ADN que codifican una proteína sintética de tela de arana que presenta la mayor similitud posible con las secuencias naturales de las proteínas fibrosas de tela de arana conocidas. Además, se ofrece un procedimiento con el que se pueden producir proteínas sintéticas de tela de arana en gran escala. Las proteínas de tela de arana conforme a la invencion pueden utilizarse para preparar hilos sintéticos así como láminas y membranas. Estos productos son apropiados especialmente para aplicaciones médicas, sobre todo para suturar heridas y/o como estructuras o como recubrimiento de organos artificiales. Además, las láminas y membranas fabricadas a partir de estas proteínas de tela de arana pueden emplearse, por ejemplo, como superficies de soporte para células cultivadas y para filtrado.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10028212 | 2000-06-09 | ||
DE10053478 | 2000-10-24 | ||
DE10113781A DE10113781A1 (de) | 2000-06-09 | 2001-03-21 | Synthetische Spinnenseidenproteine und deren Expression in transgenen Pflanzen |
Publications (1)
Publication Number | Publication Date |
---|---|
AR030426A1 true AR030426A1 (es) | 2003-08-20 |
Family
ID=27213905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP010102752A AR030426A1 (es) | 2000-06-09 | 2001-06-11 | Proteinas sinteticas de tela de arana y su expresion en plantas transgenicas |
Country Status (6)
Country | Link |
---|---|
US (1) | US20060248615A1 (es) |
EP (1) | EP1287139B1 (es) |
AR (1) | AR030426A1 (es) |
AU (1) | AU2001285735A1 (es) |
CA (1) | CA2411600A1 (es) |
WO (1) | WO2001094393A2 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6608242B1 (en) * | 2000-05-25 | 2003-08-19 | E. I. Du Pont De Nemours And Company | Production of silk-like proteins in plants |
US20070260039A1 (en) * | 2002-01-11 | 2007-11-08 | Karatzas Costas N | Methods of Producing Silk Polypeptides and Products Thereof |
US7057023B2 (en) | 2002-01-11 | 2006-06-06 | Nexia Biotechnologies Inc. | Methods and apparatus for spinning spider silk protein |
DE102007002222A1 (de) | 2007-01-10 | 2008-07-17 | Gustav Pirazzi & Comp. Kg | Verwendung von künstlich hergestellter Spinnenseide |
BRPI0701826B1 (pt) | 2007-03-16 | 2021-02-17 | Embrapa - Empresa Brasileira De Pesquisa Agropecuária | proteínas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira |
WO2008151405A1 (en) * | 2007-06-15 | 2008-12-18 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food | Expression of fusion proteins containing a single chain antibody fragment linked to elastin-like repeating units in transgenic plants |
KR101317420B1 (ko) * | 2010-03-11 | 2013-10-10 | 한국과학기술원 | 고분자량의 재조합 실크 또는 실크 유사 단백질 및 이를 이용하여 제조된 마이크로 또는 나노 크기의 거미줄 또는 거미줄 유사 섬유 |
WO2012061443A2 (en) * | 2010-11-01 | 2012-05-10 | NanoOncology, Inc. | Compositions of a peptide-based system for cell-specific targeting |
EP2518081B1 (en) | 2011-04-28 | 2017-11-29 | Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) | Method of producing and purifying polymeric proteins in transgenic plants |
US20180271939A1 (en) * | 2017-03-24 | 2018-09-27 | Milton J. Silverman, JR. | Genetic method to kill cancer cells by suffocation |
CN116425848B (zh) * | 2023-04-11 | 2024-05-24 | 北京新诚中科技术有限公司 | 重组嵌合蛛丝蛋白、生物蛋白纤维及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5770697A (en) * | 1986-11-04 | 1998-06-23 | Protein Polymer Technologies, Inc. | Peptides comprising repetitive units of amino acids and DNA sequences encoding the same |
DE69433299T2 (de) * | 1993-06-15 | 2004-09-09 | E.I. Du Pont De Nemours And Co., Wilmington | Rekombinante spinnerseide analoge |
IL123398A0 (en) * | 1995-08-22 | 1998-09-24 | Agricola Tech Inc | Cloning methods for high strength spider silk proteins |
US6608242B1 (en) * | 2000-05-25 | 2003-08-19 | E. I. Du Pont De Nemours And Company | Production of silk-like proteins in plants |
-
2001
- 2001-06-11 US US10/297,389 patent/US20060248615A1/en not_active Abandoned
- 2001-06-11 AR ARP010102752A patent/AR030426A1/es unknown
- 2001-06-11 AU AU2001285735A patent/AU2001285735A1/en not_active Abandoned
- 2001-06-11 CA CA002411600A patent/CA2411600A1/en not_active Abandoned
- 2001-06-11 WO PCT/EP2001/006586 patent/WO2001094393A2/de active Application Filing
- 2001-06-11 EP EP01964966A patent/EP1287139B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2001094393A3 (de) | 2002-06-20 |
WO2001094393A2 (de) | 2001-12-13 |
AU2001285735A1 (en) | 2001-12-17 |
CA2411600A1 (en) | 2001-12-13 |
EP1287139A2 (de) | 2003-03-05 |
US20060248615A1 (en) | 2006-11-02 |
EP1287139B1 (de) | 2010-08-25 |
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