AR019441A1 - Procedimiento para la preparacion de 2-isocianato-pirimidinas disustituidas en 4,6 y su utilizacion como productos intermedios para la sintesis desustancias activas - Google Patents
Procedimiento para la preparacion de 2-isocianato-pirimidinas disustituidas en 4,6 y su utilizacion como productos intermedios para la sintesis desustancias activasInfo
- Publication number
- AR019441A1 AR019441A1 ARP990103578A ARP990103578A AR019441A1 AR 019441 A1 AR019441 A1 AR 019441A1 AR P990103578 A ARP990103578 A AR P990103578A AR P990103578 A ARP990103578 A AR P990103578A AR 019441 A1 AR019441 A1 AR 019441A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- compound
- preparation
- alkyl
- alkynyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Procedimiento para la preparacion de compuestos de la formula (1), significando cada uno de los radicales X e Y, de modo independiente uno del otro,hidrogeno, halogeno, alquilo C1-4, alcoxi C1-4 o alquil C1-4-tio, estando cada uno de los 3 radicalesmencionados en ultimo término sin sustituir o sustituidocon uno o varios radicales tomados entre el grupo formado por halogeno, alcoxi C1-4 y alquil C1-4-tio, o significando di[alquil C1-4]-amino, cicloalquilo C3-6,alquenilo C3-5, alquinilo C3-5,alq uenil C3-5-oxi o alquinil C3-5-oxi, donde se hace reaccionar un compuesto de la formula (2) o sus sales, en la que X e Yestán definidos como en la formula (I), con 1 a 6 moles de fosgeno por 1 mol del compuesto de la formula (II), en presenciade 2 a 3,5 equivalentes molares deuna base por mol del compuesto de la formula (II) y en presencia de un disolvente orgánico aprotico, a una temperatura de reaccion situada en el margen -30 a+60*C, para formar el compuesto de la formula (I). Loscompuestos (I) se pueden convertir por reaccion con compuestos nucleofilos para formar productos dereaccion por adicion tales como carbamatos, ureas y sulfonil-ureas, y correspondientes productos, por ejemplo: sulfonil-ureas herbicidas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833007A DE19833007A1 (de) | 1998-07-23 | 1998-07-23 | Verfahren zur Herstellung von 4,6-disubstituierten 2-Isocyanatopyrimidinen und ihre Verwendung als Zwischenprodukte für Wirkstoffsynthesen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR019441A1 true AR019441A1 (es) | 2002-02-20 |
Family
ID=7874943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990103578A AR019441A1 (es) | 1998-07-23 | 1999-07-21 | Procedimiento para la preparacion de 2-isocianato-pirimidinas disustituidas en 4,6 y su utilizacion como productos intermedios para la sintesis desustancias activas |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6365739B1 (es) |
| EP (1) | EP1097144B1 (es) |
| JP (1) | JP2002521372A (es) |
| KR (1) | KR20010092263A (es) |
| CN (1) | CN1187339C (es) |
| AR (1) | AR019441A1 (es) |
| AT (1) | ATE389639T1 (es) |
| AU (1) | AU751943B2 (es) |
| BR (1) | BR9912303A (es) |
| CA (1) | CA2338349A1 (es) |
| CO (1) | CO5090922A1 (es) |
| CZ (1) | CZ2001248A3 (es) |
| DE (2) | DE19833007A1 (es) |
| HU (1) | HUP0103106A3 (es) |
| ID (1) | ID28958A (es) |
| IL (1) | IL140786A0 (es) |
| MX (1) | MXPA01000820A (es) |
| PL (1) | PL345698A1 (es) |
| RU (1) | RU2224750C2 (es) |
| TR (1) | TR200100184T2 (es) |
| TW (1) | TW520363B (es) |
| WO (1) | WO2000005220A1 (es) |
| ZA (1) | ZA200100519B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5468289B2 (ja) * | 2008-04-18 | 2014-04-09 | 石原産業株式会社 | ピリミジン系化合物の製造方法 |
| CN106349168A (zh) * | 2016-08-12 | 2017-01-25 | 淮安国瑞化工有限公司 | 磺酰脲类除草剂甲酰胺磺隆中间体的制备方法 |
| CN111423385B (zh) * | 2020-05-22 | 2022-02-18 | 北京英力精化技术发展有限公司 | 4,6-二甲氧基-2-((苯氧基羰基)氨基)-嘧啶的精制方法 |
| CN114539165A (zh) * | 2022-02-21 | 2022-05-27 | 江苏瑞邦农化股份有限公司 | 一种甲基二磺隆的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1233854B (de) * | 1965-03-03 | 1967-02-09 | Bayer Ag | Verfahren zum Herstellen von Isocyanaten |
| US4822402A (en) * | 1985-06-07 | 1989-04-18 | Ishihara Sangyo Kaisha Ltd. | Thiophenesulfonamide compounds, and herbicidal compositions containing them |
| IN164880B (es) * | 1986-01-30 | 1989-06-24 | Ishihara Sangyo Kaisha | |
| DE4206145A1 (de) * | 1992-02-28 | 1993-09-02 | Basf Ag | Herbizide n-((pyrimidin-2-yl)aminocarbonyl)benzolfulfonamide |
| DE4322726A1 (de) * | 1993-07-08 | 1995-01-12 | Basf Ag | Herbizide N-[(Pyrimidin-2-yl bzw. 1,3,5-Triazin-2-yl)aminocarbonyl]-benzolsulfonamide |
-
1998
- 1998-07-23 DE DE19833007A patent/DE19833007A1/de not_active Withdrawn
-
1999
- 1999-07-13 DE DE59914698T patent/DE59914698D1/de not_active Expired - Fee Related
- 1999-07-13 WO PCT/EP1999/004910 patent/WO2000005220A1/de active IP Right Grant
- 1999-07-13 BR BR9912303-7A patent/BR9912303A/pt not_active Application Discontinuation
- 1999-07-13 PL PL99345698A patent/PL345698A1/xx not_active Application Discontinuation
- 1999-07-13 ID IDW20010142A patent/ID28958A/id unknown
- 1999-07-13 TR TR2001/00184T patent/TR200100184T2/xx unknown
- 1999-07-13 KR KR1020017000843A patent/KR20010092263A/ko not_active Application Discontinuation
- 1999-07-13 AT AT99932871T patent/ATE389639T1/de not_active IP Right Cessation
- 1999-07-13 CN CNB998091618A patent/CN1187339C/zh not_active Expired - Fee Related
- 1999-07-13 CZ CZ2001248A patent/CZ2001248A3/cs unknown
- 1999-07-13 IL IL14078699A patent/IL140786A0/xx not_active IP Right Cessation
- 1999-07-13 AU AU49099/99A patent/AU751943B2/en not_active Ceased
- 1999-07-13 RU RU2001105095/04A patent/RU2224750C2/ru not_active IP Right Cessation
- 1999-07-13 EP EP99932871A patent/EP1097144B1/de not_active Expired - Lifetime
- 1999-07-13 CA CA002338349A patent/CA2338349A1/en not_active Abandoned
- 1999-07-13 JP JP2000561176A patent/JP2002521372A/ja not_active Abandoned
- 1999-07-13 HU HU0103106A patent/HUP0103106A3/hu unknown
- 1999-07-13 MX MXPA01000820A patent/MXPA01000820A/es unknown
- 1999-07-21 AR ARP990103578A patent/AR019441A1/es not_active Application Discontinuation
- 1999-07-21 CO CO99045931A patent/CO5090922A1/es unknown
- 1999-07-21 US US09/358,297 patent/US6365739B1/en not_active Expired - Fee Related
- 1999-07-21 TW TW088112405A patent/TW520363B/zh not_active IP Right Cessation
-
2001
- 2001-01-18 ZA ZA200100519A patent/ZA200100519B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US6365739B1 (en) | 2002-04-02 |
| ATE389639T1 (de) | 2008-04-15 |
| IL140786A0 (en) | 2002-02-10 |
| DE19833007A1 (de) | 2000-02-03 |
| PL345698A1 (en) | 2002-01-02 |
| CN1187339C (zh) | 2005-02-02 |
| TR200100184T2 (tr) | 2001-05-21 |
| JP2002521372A (ja) | 2002-07-16 |
| ZA200100519B (en) | 2001-09-19 |
| CZ2001248A3 (cs) | 2001-08-15 |
| AU751943B2 (en) | 2002-09-05 |
| EP1097144A1 (de) | 2001-05-09 |
| HUP0103106A2 (hu) | 2001-12-28 |
| TW520363B (en) | 2003-02-11 |
| AU4909999A (en) | 2000-02-14 |
| ID28958A (id) | 2001-07-19 |
| KR20010092263A (ko) | 2001-10-24 |
| RU2224750C2 (ru) | 2004-02-27 |
| CO5090922A1 (es) | 2001-10-30 |
| DE59914698D1 (de) | 2008-04-30 |
| MXPA01000820A (es) | 2002-04-08 |
| EP1097144B1 (de) | 2008-03-19 |
| HUP0103106A3 (en) | 2002-12-28 |
| WO2000005220A1 (de) | 2000-02-03 |
| CN1311782A (zh) | 2001-09-05 |
| BR9912303A (pt) | 2001-04-17 |
| CA2338349A1 (en) | 2000-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |