BR9912303A - Processo para a preparação de 2-isocianatopirimidinas 4,5-dissubstituìdas e seu emprego como produtos intermediários para sìnteses de substâncias ativas - Google Patents

Processo para a preparação de 2-isocianatopirimidinas 4,5-dissubstituìdas e seu emprego como produtos intermediários para sìnteses de substâncias ativas

Info

Publication number
BR9912303A
BR9912303A BR9912303-7A BR9912303A BR9912303A BR 9912303 A BR9912303 A BR 9912303A BR 9912303 A BR9912303 A BR 9912303A BR 9912303 A BR9912303 A BR 9912303A
Authority
BR
Brazil
Prior art keywords
formula
preparation
active substances
synthesis
intermediate products
Prior art date
Application number
BR9912303-7A
Other languages
English (en)
Inventor
Mark James Ford
Stephen Lachheinq
Original Assignee
Aventis Cropscience Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Cropscience Gmbh filed Critical Aventis Cropscience Gmbh
Publication of BR9912303A publication Critical patent/BR9912303A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Patente de Invenção: <B>''PROCESSO PARA A PREPARAçãO DE 2-ISOCIANATOPIRIMIDINAS 4,6-DISSUBSTITUìDAS E SEU EMPREGO COMO PRODUTOS INTERMEDIáRIOS PARA SìNTESES DE SUBSTâNCIAS ATIVAS''<D>. Isocianatos da fórmula (I), na qual X e Y são definidos tal como na fórmula (I) de acordo com a reivindicação (1), podem ser preparados, reagindo-se um composto da fórmula (II) ou seus sais, em que X e Y são definidos tal como na fórmula (I), com 1 até 6 moles de fosgênio para 1 mol de composto da fórmula (II), na presença de 2 até 3,5 equivalentes em mol de uma base por mol de composto da fórmula (II) e na presença de um solvente orgânico aprótico em uma temperatura de reação de -30 até +60°C para a formação do composto da fórmula (I). Os compostos (I) podem ser transformados pela reação com nucleófilos em produtos de adição, tais como carbamatos, uréias e sulfoniluréias e produtos correspondentes, por exemplo, sulfoniluréias herbicidas.
BR9912303-7A 1998-07-23 1999-07-13 Processo para a preparação de 2-isocianatopirimidinas 4,5-dissubstituìdas e seu emprego como produtos intermediários para sìnteses de substâncias ativas BR9912303A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833007A DE19833007A1 (de) 1998-07-23 1998-07-23 Verfahren zur Herstellung von 4,6-disubstituierten 2-Isocyanatopyrimidinen und ihre Verwendung als Zwischenprodukte für Wirkstoffsynthesen
PCT/EP1999/004910 WO2000005220A1 (de) 1998-07-23 1999-07-13 Verfahren zur herstellung von 4,6-disubstituierten 2-isocyanatopyrimidinen und ihre verwendung als zwischenprodukte für wirkstoffsynthesen

Publications (1)

Publication Number Publication Date
BR9912303A true BR9912303A (pt) 2001-04-17

Family

ID=7874943

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9912303-7A BR9912303A (pt) 1998-07-23 1999-07-13 Processo para a preparação de 2-isocianatopirimidinas 4,5-dissubstituìdas e seu emprego como produtos intermediários para sìnteses de substâncias ativas

Country Status (23)

Country Link
US (1) US6365739B1 (pt)
EP (1) EP1097144B1 (pt)
JP (1) JP2002521372A (pt)
KR (1) KR20010092263A (pt)
CN (1) CN1187339C (pt)
AR (1) AR019441A1 (pt)
AT (1) ATE389639T1 (pt)
AU (1) AU751943B2 (pt)
BR (1) BR9912303A (pt)
CA (1) CA2338349A1 (pt)
CO (1) CO5090922A1 (pt)
CZ (1) CZ2001248A3 (pt)
DE (2) DE19833007A1 (pt)
HU (1) HUP0103106A3 (pt)
ID (1) ID28958A (pt)
IL (1) IL140786A0 (pt)
MX (1) MXPA01000820A (pt)
PL (1) PL345698A1 (pt)
RU (1) RU2224750C2 (pt)
TR (1) TR200100184T2 (pt)
TW (1) TW520363B (pt)
WO (1) WO2000005220A1 (pt)
ZA (1) ZA200100519B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5468289B2 (ja) * 2008-04-18 2014-04-09 石原産業株式会社 ピリミジン系化合物の製造方法
CN106349168A (zh) * 2016-08-12 2017-01-25 淮安国瑞化工有限公司 磺酰脲类除草剂甲酰胺磺隆中间体的制备方法
CN111423385B (zh) * 2020-05-22 2022-02-18 北京英力精化技术发展有限公司 4,6-二甲氧基-2-((苯氧基羰基)氨基)-嘧啶的精制方法
CN114539165A (zh) * 2022-02-21 2022-05-27 江苏瑞邦农化股份有限公司 一种甲基二磺隆的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1233854B (de) * 1965-03-03 1967-02-09 Bayer Ag Verfahren zum Herstellen von Isocyanaten
US4822402A (en) * 1985-06-07 1989-04-18 Ishihara Sangyo Kaisha Ltd. Thiophenesulfonamide compounds, and herbicidal compositions containing them
IN164880B (pt) * 1986-01-30 1989-06-24 Ishihara Sangyo Kaisha
DE4206145A1 (de) * 1992-02-28 1993-09-02 Basf Ag Herbizide n-((pyrimidin-2-yl)aminocarbonyl)benzolfulfonamide
DE4322726A1 (de) * 1993-07-08 1995-01-12 Basf Ag Herbizide N-[(Pyrimidin-2-yl bzw. 1,3,5-Triazin-2-yl)aminocarbonyl]-benzolsulfonamide

Also Published As

Publication number Publication date
US6365739B1 (en) 2002-04-02
ATE389639T1 (de) 2008-04-15
IL140786A0 (en) 2002-02-10
DE19833007A1 (de) 2000-02-03
PL345698A1 (en) 2002-01-02
CN1187339C (zh) 2005-02-02
TR200100184T2 (tr) 2001-05-21
JP2002521372A (ja) 2002-07-16
ZA200100519B (en) 2001-09-19
CZ2001248A3 (cs) 2001-08-15
AU751943B2 (en) 2002-09-05
EP1097144A1 (de) 2001-05-09
HUP0103106A2 (hu) 2001-12-28
TW520363B (en) 2003-02-11
AU4909999A (en) 2000-02-14
ID28958A (id) 2001-07-19
KR20010092263A (ko) 2001-10-24
RU2224750C2 (ru) 2004-02-27
CO5090922A1 (es) 2001-10-30
DE59914698D1 (de) 2008-04-30
MXPA01000820A (es) 2002-04-08
EP1097144B1 (de) 2008-03-19
HUP0103106A3 (en) 2002-12-28
WO2000005220A1 (de) 2000-02-03
CN1311782A (zh) 2001-09-05
AR019441A1 (es) 2002-02-20
CA2338349A1 (en) 2000-02-03

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B25D Requested change of name of applicant approved

Owner name: BAYER CROPSCIENCE GMBH (DE)

Free format text: ALTERADO DE: AVENTIS CROPSCIENCE GMBH

B25A Requested transfer of rights approved

Owner name: BAYER CROPSCIENCE AG (DE)

Free format text: TRANSFERIDO POR FUSAO DE: BAYER CROPSCIENCE GMBH