AR016832A1 - Metodo para la preparacion de fenilacetilcarbinoles sin enantiomeros a partir de acetaldehido y benzaldehido en presencia de piruvatodecarboxilasade zimomonas - Google Patents
Metodo para la preparacion de fenilacetilcarbinoles sin enantiomeros a partir de acetaldehido y benzaldehido en presencia de piruvatodecarboxilasade zimomonasInfo
- Publication number
- AR016832A1 AR016832A1 ARP980104093A ARP980104093A AR016832A1 AR 016832 A1 AR016832 A1 AR 016832A1 AR P980104093 A ARP980104093 A AR P980104093A AR P980104093 A ARP980104093 A AR P980104093A AR 016832 A1 AR016832 A1 AR 016832A1
- Authority
- AR
- Argentina
- Prior art keywords
- acetaldehyde
- preparation
- zimomones
- piruvatodecarboxilasade
- phenylacetilcarbinols
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Método para la preparacion de fenilacetilcarbinoles sin enantiomeros de la formula general (I), donde R es H, F, Cl o Br, a partir de acetaldehido ybenzaldehidos de la formula general (II), en presencia de piruvatocarboxilasa de zimomonas, caracterizado porque en el curso de la biotransformacionse va agregando acetaldehido de manera continua o discontinua, de manera tal que la concentracion de acetaldehido en el medio de reaccion es de entre20 y 50 mMol/I.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19736104A DE19736104A1 (de) | 1997-08-20 | 1997-08-20 | Verfahren zur Herstellung von enantiomerenreinen Phenylacetylcarbinolen aus Acetaldchyd und Benzaldehyd in Gegenwart von Pyruvatdecarboxylase aus Zymomonas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR016832A1 true AR016832A1 (es) | 2001-08-01 |
Family
ID=7839543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104093A AR016832A1 (es) | 1997-08-20 | 1998-08-19 | Metodo para la preparacion de fenilacetilcarbinoles sin enantiomeros a partir de acetaldehido y benzaldehido en presencia de piruvatodecarboxilasade zimomonas |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1009848A1 (es) |
| JP (1) | JP2001514899A (es) |
| AR (1) | AR016832A1 (es) |
| AU (1) | AU8732798A (es) |
| DE (1) | DE19736104A1 (es) |
| WO (1) | WO1999009195A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19918935A1 (de) * | 1999-04-27 | 2000-11-02 | Forschungszentrum Juelich Gmbh | Stereoselektive Synthese von 2-Hydroxyketonen |
| DE10032254B4 (de) * | 2000-07-03 | 2006-05-04 | Forschungszentrum Jülich GmbH | Nukleotidsequenz kodierend für eine Benzaldehyd-Lyase und Verfahren zur stereoselektiven Synthese von (R)-2-Hydroxyketonen |
| DE10032058A1 (de) * | 2000-07-05 | 2002-01-17 | Basf Ag | Mikrobielle Produktion von R-Phenylacetylcarbinol durch biologische Umwandlung von Benzaldehyd durch filamentöse Pilze |
| DE10142467A1 (de) | 2001-08-31 | 2003-03-20 | Basf Ag | Neue Pyruvatdecarboxylase, ihre Herstellung und Verwendung |
| DE10142574A1 (de) * | 2001-09-01 | 2003-03-20 | Basf Ag | Verfahren zur Herstellung von R-Phenylacetylcarbinol durch ein enzymatisches verfahren in einem Zweiphasensystem |
| JP2010017094A (ja) * | 2008-07-08 | 2010-01-28 | Thermostable Enzyme Laboratory Co Ltd | 酵素反応によりアセトアルデヒドを製造する方法 |
| DE102013009631A1 (de) * | 2013-06-10 | 2014-12-11 | Forschungszentrum Jülich GmbH | Verfahren zur Herstellung von Cathin |
| DE102017210944B4 (de) | 2017-06-28 | 2019-05-23 | Technische Universität Dresden | Alkoholdehydrogenasen und Verfahren zur stereoselektiven Reduktion von Carbonylverbindungen |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19523269C2 (de) * | 1995-05-26 | 2000-05-31 | Forschungszentrum Juelich Gmbh | Verfahren zur Gewinnung von Acyloinen, dafür geeignete Pyruvat-decarboxylase sowie deren Herstellung und DNA-Sequenz des für diese kodierenden PDC-Gens |
-
1997
- 1997-08-20 DE DE19736104A patent/DE19736104A1/de not_active Withdrawn
-
1998
- 1998-07-25 AU AU87327/98A patent/AU8732798A/en not_active Abandoned
- 1998-07-25 WO PCT/EP1998/004672 patent/WO1999009195A1/de not_active Application Discontinuation
- 1998-07-25 JP JP2000509857A patent/JP2001514899A/ja not_active Withdrawn
- 1998-07-25 EP EP98938706A patent/EP1009848A1/de not_active Withdrawn
- 1998-08-19 AR ARP980104093A patent/AR016832A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001514899A (ja) | 2001-09-18 |
| DE19736104A1 (de) | 1999-02-25 |
| WO1999009195A1 (de) | 1999-02-25 |
| AU8732798A (en) | 1999-03-08 |
| EP1009848A1 (de) | 2000-06-21 |
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