AR015035A1 - Agentes serotonergicos, composicion farmaceutica que los contiene y su uso para la manufactura de un medicamento - Google Patents

Agentes serotonergicos, composicion farmaceutica que los contiene y su uso para la manufactura de un medicamento

Info

Publication number
AR015035A1
AR015035A1 ARP990101974A ARP990101974A AR015035A1 AR 015035 A1 AR015035 A1 AR 015035A1 AR P990101974 A ARP990101974 A AR P990101974A AR P990101974 A ARP990101974 A AR P990101974A AR 015035 A1 AR015035 A1 AR 015035A1
Authority
AR
Argentina
Prior art keywords
manufacture
pharmaceutical composition
serotonergic agents
alkyl
medicinal product
Prior art date
Application number
ARP990101974A
Other languages
English (en)
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of AR015035A1 publication Critical patent/AR015035A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)

Abstract

Agentes serotonérgicos representados por la formula general (1) en donde: R1 se selecciona entre H, OH, OR2, o halogeno (F, Cl, Br, I); R3 es alquiloinferior C1-6; (CH2)nAr; n es un numero entero seleccionado entre 0, 1 o 2; X es CH o CH2; R2 es H oen conjunto es O; Ar se selecciona entre fenilo, bencilo,piridinilo, pirimidinilo, pirazinilo, furilo, tienilo, pirrolilo, indolilo, naftilo, benzodioxanilo o quinililo, cada uno optativamente sustituido con entreuno a tres grupos seleccionados entreF, Cl, Br, I, -OH, -OR3, alquilo C1-6, alcoxi C1-6-CF3-CN, -S-alquilo C1-6 o NH2; o su sal farmacéuticamente aceptable,composiciones farmacéuticas que utilizan estos compuestos para la inhibicion de la absorcion de serotonina y el tratamiento de trstornos en el SNC,particularmente la depresion y suuso para la manufactura de un medicamento.
ARP990101974A 1998-04-29 1999-04-28 Agentes serotonergicos, composicion farmaceutica que los contiene y su uso para la manufactura de un medicamento AR015035A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6904198A 1998-04-29 1998-04-29

Publications (1)

Publication Number Publication Date
AR015035A1 true AR015035A1 (es) 2001-04-11

Family

ID=22086346

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990101974A AR015035A1 (es) 1998-04-29 1999-04-28 Agentes serotonergicos, composicion farmaceutica que los contiene y su uso para la manufactura de un medicamento

Country Status (7)

Country Link
EP (1) EP1076658A1 (es)
JP (1) JP2002513018A (es)
CN (1) CN1307576A (es)
AR (1) AR015035A1 (es)
AU (1) AU3765899A (es)
CA (1) CA2330577A1 (es)
WO (1) WO1999055697A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002243394A1 (en) * 2000-11-16 2002-06-24 Wyeth Aryloxy piperidinyl derivatives for the treatment of depression
PL363238A1 (en) * 2000-12-22 2004-11-15 Wyeth Heterocyclylalkylindole or -azaindole compounds as 5-hydroxytryptamine-6 ligands
AR072297A1 (es) 2008-06-27 2010-08-18 Novartis Ag Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona.
CN107205970A (zh) 2014-11-05 2017-09-26 弗莱塞斯生物科学公司 免疫调节剂
UY36390A (es) * 2014-11-05 2016-06-01 Flexus Biosciences Inc Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1271352B (it) * 1993-04-08 1997-05-27 Boehringer Ingelheim Italia Derivati dell'indolo utili nel trattamento dei disturbi del sistema nervoso centrale
DE19615232A1 (de) * 1996-04-18 1997-10-23 Merck Patent Gmbh Neue Carbamoylderivate und deren Verwendung als 5-HT ¶1¶¶A¶-Antagonisten
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake

Also Published As

Publication number Publication date
WO1999055697A1 (en) 1999-11-04
AU3765899A (en) 1999-11-16
CA2330577A1 (en) 1999-11-04
JP2002513018A (ja) 2002-05-08
CN1307576A (zh) 2001-08-08
EP1076658A1 (en) 2001-02-21

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