AR014341A1 - USO DE POLIMEROS OPTICAMENTE ACTIVOS DE N-ACRILOIL-S-FENILALANINA-d- NEOMENTILAMIDA O DE SU ENANTIOMERO Y PROCEDIMIENTO PARA LA SEPARACIONCROMATOGRAFICA DE ENANTIOMEROS DE LACTONAS - Google Patents
USO DE POLIMEROS OPTICAMENTE ACTIVOS DE N-ACRILOIL-S-FENILALANINA-d- NEOMENTILAMIDA O DE SU ENANTIOMERO Y PROCEDIMIENTO PARA LA SEPARACIONCROMATOGRAFICA DE ENANTIOMEROS DE LACTONASInfo
- Publication number
- AR014341A1 AR014341A1 ARP980101599A ARP980101599A AR014341A1 AR 014341 A1 AR014341 A1 AR 014341A1 AR P980101599 A ARP980101599 A AR P980101599A AR P980101599 A ARP980101599 A AR P980101599A AR 014341 A1 AR014341 A1 AR 014341A1
- Authority
- AR
- Argentina
- Prior art keywords
- enantiomers
- chromatographic separation
- enantiomer
- phenylalanine
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/282—Porous sorbents
- B01J20/285—Porous sorbents based on polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/29—Chiral phases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3204—Inorganic carriers, supports or substrates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
El uso de polímeros opticamente activos de N-acriloil-S-fenilalanina-d- neomentilamida o de su enantiomero, como tales, en forma reticulada y/o enforma unida a un soporte como fases estacionarias que se destina para la separacion cromatográfica de enantiomeros de lactona de formula general (I),en la que: R representa un resto orgánico y X representa -CH2-CH2- o -CH=CH- y un procedimiento para la separacion cromatográfica de enantiomeros de lactonas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19714343A DE19714343A1 (de) | 1997-04-08 | 1997-04-08 | Chromatographische Enantiomerentrennung von Lactonen |
Publications (1)
Publication Number | Publication Date |
---|---|
AR014341A1 true AR014341A1 (es) | 2001-02-28 |
Family
ID=7825712
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP980101599A AR014341A1 (es) | 1997-04-08 | 1998-04-07 | USO DE POLIMEROS OPTICAMENTE ACTIVOS DE N-ACRILOIL-S-FENILALANINA-d- NEOMENTILAMIDA O DE SU ENANTIOMERO Y PROCEDIMIENTO PARA LA SEPARACIONCROMATOGRAFICA DE ENANTIOMEROS DE LACTONAS |
Country Status (10)
Country | Link |
---|---|
US (2) | US6274736B1 (es) |
EP (1) | EP0973705B1 (es) |
JP (1) | JP2001521507A (es) |
AR (1) | AR014341A1 (es) |
AT (1) | ATE300509T1 (es) |
AU (1) | AU7211298A (es) |
DE (2) | DE19714343A1 (es) |
DK (1) | DK0973705T3 (es) |
WO (1) | WO1998045230A1 (es) |
ZA (1) | ZA982948B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10135013A1 (de) * | 2001-07-18 | 2003-01-30 | Bayer Ag | Herstellung von Pyridylverbindungen |
EP1463637B1 (de) * | 2002-01-10 | 2008-07-02 | Bundesdruckerei GmbH | Wert- oder sicherheitsdokument mit einem schalter |
US7501613B2 (en) | 2003-07-08 | 2009-03-10 | Lightswitch Safety Systems, Inc. | Light detecting and angle of view compensation for optical devices and method |
US20090135735A1 (en) * | 2007-11-27 | 2009-05-28 | Tellabs Operations, Inc. | Method and apparatus of RTP control protocol (RTCP) processing in real-time transport protocol (RTP) intermediate systems |
US20090135724A1 (en) * | 2007-11-27 | 2009-05-28 | Tellabs Operations, Inc. | Method and apparatus of RTP control protocol (RTCP) processing in real-time transport protocol (RTP) intermediate systems |
US8639739B1 (en) * | 2007-12-27 | 2014-01-28 | Amazon Technologies, Inc. | Use of peer-to-peer teams to accomplish a goal |
SG11201605712SA (en) | 2014-01-16 | 2016-08-30 | Grace W R & Co | Affinity chromatography media and chromatography devices |
ES2929099T3 (es) | 2014-05-02 | 2022-11-24 | Grace W R & Co | Material de soporte funcionalizado y métodos de fabricación y uso de material de soporte funcionalizado |
BR112017026193B1 (pt) | 2015-06-05 | 2021-09-14 | W.R. Grace & Co-Conn | Adsorventes, método de produção dos adsorventes e uso dos adsorventes |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60196663A (ja) * | 1984-03-19 | 1985-10-05 | Daicel Chem Ind Ltd | 分離剤 |
US4855481A (en) | 1984-11-19 | 1989-08-08 | Merck Frosst Canada, Inc. | Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein |
US4611068A (en) | 1984-11-19 | 1986-09-09 | Merck Frosst Canada, Inc. | Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein |
DE3532356A1 (de) * | 1985-09-11 | 1987-03-19 | Bayer Ag | Optisch aktive (meth)-acrylamide, polymere daraus, verfahren zu ihrer herstellung und ihre verwendung zur racematspaltung |
JPS6396163A (ja) * | 1986-10-11 | 1988-04-27 | バイエル・アクチエンゲゼルシヤフト | 光学活性なアクリルアミド及びメタアクリルアミド、それらの重合体、それらの製法と利用 |
US4897490A (en) * | 1987-02-25 | 1990-01-30 | Bristol-Meyers Company | Antihypercholesterolemic tetrazole compounds |
DE3706890A1 (de) | 1987-03-04 | 1988-09-15 | Bayer Ag | Optisch aktive (meth)acrylamide, verfahren zu ihrer herstellung und ihre verwendung zur racematspaltung |
DE3741509A1 (de) | 1987-12-08 | 1989-06-22 | Hoechst Ag | Verfahren zur herstellung optisch aktiver 3-desmethylmevalonsaeurederivate sowie zwischenprodukte |
ATE126207T1 (de) * | 1989-01-26 | 1995-08-15 | Bayer Ag | Optisch aktive (meth)acrylsäure-derivate, ihre herstellung, ihre polymerisation zu optisch aktiven polymeren und deren verwendung. |
US5274167A (en) | 1989-01-26 | 1993-12-28 | Bayer Aktiengesellschaft | Polymeriable optically active (meth) acrylic acid derivatives |
FI94339C (fi) * | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
US4992429A (en) | 1989-08-24 | 1991-02-12 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Novel HMG-COA reductase inhibitors |
US5177080A (en) | 1990-12-14 | 1993-01-05 | Bayer Aktiengesellschaft | Substituted pyridyl-dihydroxy-heptenoic acid and its salts |
AU2023292A (en) | 1991-02-11 | 1992-09-15 | Rhone-Poulenc Rorer International (Holdings) Inc. | Enantioselective preparation of acetylenic or olefinic substituted cycloalkenyl dihydroxybutyrates and 4-hydroxy-tetrahydropyran-2-ones |
DE4120695A1 (de) * | 1991-06-22 | 1992-12-24 | Bayer Ag | Optisch aktive schwefelhaltige aminosaeure-derivate, ihre herstellung, ihre polymerisation zu optisch aktiven polymeren und deren verwendung |
JPH08500576A (ja) * | 1992-06-30 | 1996-01-23 | レゴマー パートナーズ,エル.ピー. | オキサゾロンから誘導される物質 |
JPH075161A (ja) * | 1992-11-10 | 1995-01-10 | Chuichi Hirayama | 高性能液体クロマトグラフィー用充填剤 |
DE4309553A1 (de) * | 1993-03-24 | 1994-09-29 | Bayer Ag | Verfahren zur Herstellung von 3R,5S-(+)-Natrium-erythro-(E)-7-(4-(4-flurophenyl)-2,6-diisopropyl-5-methoxymethyl-pyrid-3-yl)-3,5-dihydroxy-hept-6-enoat |
JPH07126193A (ja) * | 1993-11-05 | 1995-05-16 | Hisanori Fukumoto | 高級脂肪酸類、高級アルコール類および芳香族化合物類の精製方法 |
DE19546136A1 (de) | 1995-12-11 | 1997-06-12 | Bayer Ag | Chirale stationäre Phasen für die chromatographische Trennung von optischen Isomeren |
-
1997
- 1997-04-08 DE DE19714343A patent/DE19714343A1/de not_active Withdrawn
-
1998
- 1998-03-26 AT AT98919159T patent/ATE300509T1/de not_active IP Right Cessation
- 1998-03-26 DK DK98919159T patent/DK0973705T3/da active
- 1998-03-26 US US09/380,332 patent/US6274736B1/en not_active Expired - Fee Related
- 1998-03-26 DE DE59812963T patent/DE59812963D1/de not_active Expired - Lifetime
- 1998-03-26 WO PCT/EP1998/001788 patent/WO1998045230A1/de active IP Right Grant
- 1998-03-26 EP EP98919159A patent/EP0973705B1/de not_active Expired - Lifetime
- 1998-03-26 AU AU72112/98A patent/AU7211298A/en not_active Abandoned
- 1998-03-26 JP JP54231798A patent/JP2001521507A/ja not_active Ceased
- 1998-04-07 AR ARP980101599A patent/AR014341A1/es not_active Application Discontinuation
- 1998-04-07 ZA ZA982948A patent/ZA982948B/xx unknown
-
2001
- 2001-01-10 US US09/757,919 patent/US6689889B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1998045230A1 (de) | 1998-10-15 |
AU7211298A (en) | 1998-10-30 |
US6689889B2 (en) | 2004-02-10 |
DE59812963D1 (de) | 2005-09-01 |
ATE300509T1 (de) | 2005-08-15 |
EP0973705A1 (de) | 2000-01-26 |
US20020133017A1 (en) | 2002-09-19 |
US6274736B1 (en) | 2001-08-14 |
JP2001521507A (ja) | 2001-11-06 |
DE19714343A1 (de) | 1998-10-15 |
DK0973705T3 (da) | 2005-11-07 |
EP0973705B1 (de) | 2005-07-27 |
ZA982948B (en) | 1998-10-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |