AR008486A1 - Nuevas heteroariloxietilaminas, procedimiento para su fabricacion, medicamentos y composiciones farmaceuticas que las contienen, su uso y nuevosproductos industriales utilizados en dicho procedimiento. - Google Patents

Nuevas heteroariloxietilaminas, procedimiento para su fabricacion, medicamentos y composiciones farmaceuticas que las contienen, su uso y nuevosproductos industriales utilizados en dicho procedimiento.

Info

Publication number
AR008486A1
AR008486A1 ARP970104385A ARP970104385A AR008486A1 AR 008486 A1 AR008486 A1 AR 008486A1 AR P970104385 A ARP970104385 A AR P970104385A AR P970104385 A ARP970104385 A AR P970104385A AR 008486 A1 AR008486 A1 AR 008486A1
Authority
AR
Argentina
Prior art keywords
procedure
new
manufacture
pharmaceutical compositions
industrial products
Prior art date
Application number
ARP970104385A
Other languages
English (en)
Original Assignee
Ipsen Pharma Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Pharma Sas filed Critical Ipsen Pharma Sas
Publication of AR008486A1 publication Critical patent/AR008486A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invencion se refiere a nuevas héteroariloxietilaminas que tienen una elevada afinidad por el receptor 5-HT1A, un procedimiento para sufabricacion, medicamentos y composiciones farmacéuticas que las contienen, su uso especialmentecomo inhibidores de la secrecion de ácido gástrico y comoanti-eméticos, y nuevos productos industriales utilizados en dicho procedimiento. Las referidas héteroariloxietilaminas responden a la formulageneral I; donde Ar representa unradi cal héteroarilo bicíclico sustituído optativamente con uno o más substituyentes; Y representa -C(O)NH- o -NHC(O)-;y R representa un radical alquilo inferior, un radical cicloalquilo sustituído con uno o más radicales alquilo inferior; o unfenil o substituído optativamentecon uno o más substituyentes seleccionados entre radicales hidroxi, ciano, halo, trifluorometilo, alquilo inferior y alcoxi inferior; y sales de estoscompuestos.
ARP970104385A 1996-09-27 1997-09-24 Nuevas heteroariloxietilaminas, procedimiento para su fabricacion, medicamentos y composiciones farmaceuticas que las contienen, su uso y nuevosproductos industriales utilizados en dicho procedimiento. AR008486A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9611798A FR2753968B1 (fr) 1996-09-27 1996-09-27 Nouvelles heteroaryloxyethylamines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
AR008486A1 true AR008486A1 (es) 2000-01-19

Family

ID=9496126

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970104385A AR008486A1 (es) 1996-09-27 1997-09-24 Nuevas heteroariloxietilaminas, procedimiento para su fabricacion, medicamentos y composiciones farmaceuticas que las contienen, su uso y nuevosproductos industriales utilizados en dicho procedimiento.

Country Status (21)

Country Link
US (1) US6063784A (es)
EP (1) EP0929525B1 (es)
JP (1) JP2001503393A (es)
AR (1) AR008486A1 (es)
AT (1) ATE223380T1 (es)
AU (1) AU731459B2 (es)
BR (1) BR9711560A (es)
CA (1) CA2267247C (es)
DE (1) DE69715223T2 (es)
DK (1) DK0929525T3 (es)
ES (1) ES2182120T3 (es)
FR (1) FR2753968B1 (es)
HU (1) HUP0001189A3 (es)
IL (1) IL128917A (es)
MY (1) MY118992A (es)
NO (1) NO311935B1 (es)
NZ (1) NZ334623A (es)
PL (1) PL190221B1 (es)
RU (1) RU2176639C2 (es)
TW (1) TW425390B (es)
WO (1) WO1998013349A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4507398B2 (ja) * 1999-12-06 2010-07-21 宇部興産株式会社 ３−ハロメチルオキセタン化合物の合成方法
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
AU645681B2 (en) * 1991-05-02 1994-01-20 John Wyeth & Brother Limited Piperazine derivatives
US5240800A (en) * 1991-07-29 1993-08-31 Eastman Kodak Company Near-infrared radiation sensitive photoelectrographic master and imaging method
GB9507288D0 (en) * 1995-04-07 1995-05-31 Sod Conseils Rech Applic Phenoxyethylamine derivatives with high affinity for 5-HT1A receptors

Also Published As

Publication number Publication date
ES2182120T3 (es) 2003-03-01
EP0929525B1 (fr) 2002-09-04
US6063784A (en) 2000-05-16
ATE223380T1 (de) 2002-09-15
NZ334623A (en) 1999-09-29
DK0929525T3 (da) 2002-12-02
IL128917A (en) 2003-10-31
NO991481L (no) 1999-03-26
DE69715223D1 (de) 2002-10-10
IL128917A0 (en) 2000-02-17
CA2267247A1 (fr) 1998-04-02
TW425390B (en) 2001-03-11
BR9711560A (pt) 1999-08-24
NO311935B1 (no) 2002-02-18
CA2267247C (fr) 2009-05-05
AU731459B2 (en) 2001-03-29
RU2176639C2 (ru) 2001-12-10
HUP0001189A2 (hu) 2000-10-28
AU4463797A (en) 1998-04-17
PL190221B1 (pl) 2005-11-30
FR2753968B1 (fr) 1998-11-27
MY118992A (en) 2005-02-28
HUP0001189A3 (en) 2001-12-28
JP2001503393A (ja) 2001-03-13
FR2753968A1 (fr) 1998-04-03
DE69715223T2 (de) 2003-04-30
WO1998013349A3 (fr) 1998-11-05
EP0929525A2 (fr) 1999-07-21
PL332480A1 (en) 1999-09-13
WO1998013349A2 (fr) 1998-04-02
NO991481D0 (no) 1999-03-26

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