AP2014007548A0 - Selective androgen receptor modulators - Google Patents

Selective androgen receptor modulators

Info

Publication number
AP2014007548A0
AP2014007548A0 AP2014007548A AP2014007548A AP2014007548A0 AP 2014007548 A0 AP2014007548 A0 AP 2014007548A0 AP 2014007548 A AP2014007548 A AP 2014007548A AP 2014007548 A AP2014007548 A AP 2014007548A AP 2014007548 A0 AP2014007548 A0 AP 2014007548A0
Authority
AP
ARIPO
Prior art keywords
androgen receptor
receptor modulators
selective androgen
selective
modulators
Prior art date
Application number
AP2014007548A
Other languages
English (en)
Inventor
Prabhakar Kondaji Jadhav
Ashraf Saeed
Jonathan Edward Green
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47046879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2014007548(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of AP2014007548A0 publication Critical patent/AP2014007548A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/22—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
AP2014007548A 2011-10-13 2012-10-05 Selective androgen receptor modulators AP2014007548A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161546711P 2011-10-13 2011-10-13
PCT/US2012/058824 WO2013055577A1 (en) 2011-10-13 2012-10-05 Selective androgen receptor modulators

Publications (1)

Publication Number Publication Date
AP2014007548A0 true AP2014007548A0 (en) 2014-03-31

Family

ID=47046879

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2014007548A AP2014007548A0 (en) 2011-10-13 2012-10-05 Selective androgen receptor modulators

Country Status (27)

Country Link
US (1) US8658693B2 (zh)
EP (1) EP2766350B1 (zh)
JP (1) JP6002228B2 (zh)
KR (1) KR20140067102A (zh)
CN (1) CN103842348B (zh)
AP (1) AP2014007548A0 (zh)
AR (1) AR088082A1 (zh)
AU (1) AU2012321113B2 (zh)
BR (1) BR112014008668A2 (zh)
CA (1) CA2847889A1 (zh)
CL (1) CL2014000895A1 (zh)
CO (1) CO6910195A2 (zh)
CR (1) CR20140156A (zh)
DO (1) DOP2014000075A (zh)
EA (1) EA201490519A1 (zh)
EC (1) ECSP14013305A (zh)
ES (1) ES2626820T3 (zh)
GT (1) GT201400067A (zh)
IL (1) IL231440A0 (zh)
MX (1) MX2014004558A (zh)
PE (1) PE20141669A1 (zh)
PL (1) PL2766350T3 (zh)
PT (1) PT2766350T (zh)
SG (1) SG11201401794YA (zh)
TN (1) TN2014000136A1 (zh)
TW (1) TWI449686B (zh)
WO (1) WO2013055577A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140045856A1 (en) 2012-07-31 2014-02-13 Boehringer Ingelheim International Gmbh 4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes
TW201534586A (zh) * 2013-06-11 2015-09-16 Orion Corp 新穎ｃｙｐ１７抑制劑／抗雄激素劑
ES2693520T3 (es) 2013-12-04 2018-12-12 Evotec International Gmbh Quinazolinas sustituidas con sulfoximina para composiciones farmacéuticas
US9682960B2 (en) 2013-12-19 2017-06-20 Endorecherche, Inc. Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety
ES2749186T3 (es) 2014-05-07 2020-03-19 Evotec Int Gmbh Quinazolinas sustituidas con sulfoximina para composiciones farmacéuticas
TN2019000039A1 (en) 2016-08-15 2020-07-15 Pfizer Pyridopyrimdinone cdk2/4/6 inhibitors
SG11201901525XA (en) 2016-09-02 2019-03-28 Suven Life Sciences Ltd Muscarinic m1 receptor positive allosteric modulators
WO2019052932A1 (en) 2017-09-18 2019-03-21 Basf Se SUBSTITUTED TRIFLUOROMETHYLOXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594405A (en) * 1968-05-17 1971-07-20 Du Pont Substituted pyranyl anilines as plant growth modifiers
EP1256578B1 (en) * 2001-05-11 2006-01-11 Pfizer Products Inc. Thiazole derivatives and their use as cdk inhibitors
WO2005090282A1 (en) * 2004-03-12 2005-09-29 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
CA2608419A1 (en) * 2005-05-13 2006-11-23 Eli Lilly And Company Substituted n-arylpyrrolidines as selective androgen receptor modulators
AU2006319916A1 (en) * 2005-11-30 2007-06-07 Astellas Pharma Inc. 2-aminobenzamide derivative
EP2146967A2 (en) * 2007-04-16 2010-01-27 Serenex, Inc. Tetrahydroindole and tetrahydroindazole derivatives
WO2009052514A2 (en) * 2007-10-19 2009-04-23 Michelle Letendre-Hedlund Methods of identifying environmentally friendly businesses or individuals
BRPI0907844B8 (pt) * 2008-02-22 2021-05-25 Radius Health Inc compostos e método para modular um receptor de andrógeno, processos de preparação e composição farmacêutica dos mesmos e seus usos

Also Published As

Publication number Publication date
PL2766350T3 (pl) 2017-08-31
KR20140067102A (ko) 2014-06-03
PE20141669A1 (es) 2014-11-08
CO6910195A2 (es) 2014-03-31
TWI449686B (zh) 2014-08-21
JP6002228B2 (ja) 2016-10-05
EP2766350A1 (en) 2014-08-20
ES2626820T3 (es) 2017-07-26
AU2012321113B2 (en) 2015-07-09
GT201400067A (es) 2015-02-27
US20130217762A1 (en) 2013-08-22
AR088082A1 (es) 2014-05-07
AU2012321113A1 (en) 2014-03-27
EA201490519A1 (ru) 2014-09-30
TW201329026A (zh) 2013-07-16
BR112014008668A2 (pt) 2017-04-25
EP2766350B1 (en) 2017-04-05
WO2013055577A1 (en) 2013-04-18
CN103842348B (zh) 2015-08-19
US8658693B2 (en) 2014-02-25
MX2014004558A (es) 2014-08-01
ECSP14013305A (es) 2014-05-31
JP2014530818A (ja) 2014-11-20
DOP2014000075A (es) 2014-06-01
PT2766350T (pt) 2017-05-22
CR20140156A (es) 2014-05-16
IL231440A0 (en) 2014-04-30
TN2014000136A1 (en) 2015-07-01
CL2014000895A1 (es) 2014-08-22
CA2847889A1 (en) 2013-04-18
SG11201401794YA (en) 2014-09-26
CN103842348A (zh) 2014-06-04

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