AP2012006292A0 - Topical use of hydroxytyrosol and derivatives for the prevention of HIV infection. - Google Patents

Topical use of hydroxytyrosol and derivatives for the prevention of HIV infection.

Info

Publication number
AP2012006292A0
AP2012006292A0 AP2012006292A AP2012006292A AP2012006292A0 AP 2012006292 A0 AP2012006292 A0 AP 2012006292A0 AP 2012006292 A AP2012006292 A AP 2012006292A AP 2012006292 A AP2012006292 A AP 2012006292A AP 2012006292 A0 AP2012006292 A0 AP 2012006292A0
Authority
AP
ARIPO
Prior art keywords
hydroxytyrosol
prevention
derivatives
hiv infection
topical use
Prior art date
Application number
AP2012006292A
Other languages
English (en)
Inventor
Eduardo Gomez-Acebo
Pertejo Jose Alcami
Calles David Aunon
Original Assignee
Seprox Biotech Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seprox Biotech Sl filed Critical Seprox Biotech Sl
Publication of AP2012006292A0 publication Critical patent/AP2012006292A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
AP2012006292A 2009-12-01 2010-12-01 Topical use of hydroxytyrosol and derivatives for the prevention of HIV infection. AP2012006292A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09382267 2009-12-01
PCT/EP2010/068673 WO2011067302A1 (en) 2009-12-01 2010-12-01 Topical use of hydroxytyrosol and derivatives for the prevention of hiv infection

Publications (1)

Publication Number Publication Date
AP2012006292A0 true AP2012006292A0 (en) 2012-06-30

Family

ID=43800358

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2012006292A AP2012006292A0 (en) 2009-12-01 2010-12-01 Topical use of hydroxytyrosol and derivatives for the prevention of HIV infection.

Country Status (13)

Country Link
US (1) US20120260922A1 (xx)
EP (1) EP2506841A1 (xx)
JP (1) JP2013512275A (xx)
KR (1) KR20120099473A (xx)
CN (1) CN102711745A (xx)
AP (1) AP2012006292A0 (xx)
AU (1) AU2010326618A1 (xx)
BR (1) BR112012013252A2 (xx)
CA (1) CA2782441A1 (xx)
MX (1) MX2012006297A (xx)
NZ (1) NZ600912A (xx)
RU (1) RU2560879C2 (xx)
WO (1) WO2011067302A1 (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
CN103122025B (zh) * 2011-11-21 2017-09-05 中国人民解放军军事医学科学院毒物药物研究所 抑制hiv感染的小分子‑多肽缀合物
EP2925307B1 (en) * 2012-11-30 2020-10-28 McCord, Darlene E. Hydroxytyrosol and oleuropein compositions for induction of dna damage, cell death and lsd1 inhibition
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US9919034B2 (en) 2014-03-28 2018-03-20 Tamir Biotechnology, Inc. Methods of treating and prophylactically protecting mammalian patients infected by viruses classified in Baltimore group V
US9642794B2 (en) * 2014-08-18 2017-05-09 Tamir Biotechnology, Inc. Antiviral pharmaceutical for topical administration
US10835598B2 (en) 2014-08-18 2020-11-17 Orgenesis Inc. Prophylactic protection against viral infections, particularly HIV
US20160045574A1 (en) * 2014-08-18 2016-02-18 Tamir Biotechnology, Inc. Antiviral pharmaceutical for topical administration
KR20180026455A (ko) 2015-06-15 2018-03-12 타미르 바이오테크놀로지 인코포레이티드 눈의 바이러스 감염의 치료를 위한 의약
CN108676067B (zh) * 2018-03-23 2019-09-06 广州朗圣药业有限公司 一种预防hiv感染的新化合物及其制备方法
CN109010329A (zh) * 2018-09-29 2018-12-18 西安交通大学 羟基酪醇醋酸酯在改善血管内皮功能障碍疾病中的应用

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2149240A (en) 1938-05-19 1939-02-28 Calco Chemical Co Inc Vaginal preparation
US2330846A (en) 1939-05-01 1943-10-05 Ortho Products Inc Spermicide
US2467884A (en) 1944-02-02 1949-04-19 Nathaniel M Elias Spermicides
US2436184A (en) 1945-11-08 1948-02-17 Eaton Lab Inc Pharmaceutical jelly
US2541103A (en) 1948-04-27 1951-02-13 Ortho Pharma Corp Spermicidal composition
US2623841A (en) 1950-11-21 1952-12-30 Schmid Inc Julius Spermicidal compositions
US2623839A (en) 1950-11-21 1952-12-30 Schmid Inc Julius Spermicidal compositions
US3062715A (en) 1953-11-18 1962-11-06 George S Pfaus Vaginal tablet
US3067743A (en) 1958-11-12 1962-12-11 Alginate Ind Ltd Alginic compounds
US3108043A (en) 1960-05-09 1963-10-22 Ortho Pharma Corp Spermicidal sheet-like material
US3174900A (en) 1962-10-10 1965-03-23 Holland Rantos Company Inc Thioether spermicidal method and composition
US3244589A (en) 1962-10-26 1966-04-05 Sunnen Alkyl phenoxy polyethoxy ether spermicidal aerosol
US3916898A (en) 1964-05-20 1975-11-04 Searle & Co Administration of medicaments and the like
US3887699A (en) 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US3640741A (en) 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
FR2097520A5 (xx) 1970-07-09 1972-03-03 Morel Paul
US3888975A (en) 1972-12-27 1975-06-10 Alza Corp Erodible intrauterine device
US4017641A (en) 1975-01-31 1977-04-12 The Procter & Gamble Company Skin moisturizing compositions containing 2-pyrrolidinone
US3989816A (en) 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4011312A (en) 1975-06-25 1977-03-08 American Home Products Corporation Prolonged release drug form for the treatment of bovine mastitis
IT1039699B (it) 1975-07-03 1979-12-10 Prephar Composizione spermicida a base di derivati benzisotiazolici
US4130667A (en) 1976-01-12 1978-12-19 The Procter & Gamble Company Dermatological compositions
US4108309A (en) 1976-10-15 1978-08-22 All One God Faith, Inc. Contraceptive containing device
FR2433949A1 (fr) 1978-08-25 1980-03-21 Commissariat Energie Atomique Substrat hydrophobe apte a liberer une substance chimique
US4321277A (en) 1978-12-04 1982-03-23 Research Lab Products, Inc. Germicidal use of compositions containing certain quaternary ammonium compounds
US4187286A (en) 1979-01-02 1980-02-05 G&W Laboratories, Inc. Contraceptive suppository
US4954487A (en) 1979-01-08 1990-09-04 The Procter & Gamble Company Penetrating topical pharmaceutical compositions
US4360013A (en) 1980-04-21 1982-11-23 Minnesota Mining And Manufacturing Company Polymeric acid contraceptive devices
IT1131833B (it) 1980-06-20 1986-06-25 Crinos Industria Farmaco Eccipienti per sostanze spermicide
US4389330A (en) 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US4368186A (en) 1981-05-07 1983-01-11 Syntex (U.S.A.) Inc. Methods and compositions for intravaginal contraception
US4415585A (en) 1982-03-11 1983-11-15 University Of Illinois Foundation Contraceptive method
US5248700A (en) 1982-05-14 1993-09-28 Akzo Nv Active agent containing solid structures for prolonged release of active agents
US4961931A (en) 1982-07-29 1990-10-09 Alza Corporation Method for the management of hyperplasia
US4499154A (en) 1982-09-03 1985-02-12 Howard L. Podell Dipped rubber article
US4551148A (en) 1982-09-07 1985-11-05 Kv Pharmaceutical Company Vaginal delivery systems and their methods of preparation and use
US4537776A (en) 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US4557934A (en) 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
US4552872A (en) 1983-06-21 1985-11-12 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing corticosteroids
US4589880A (en) 1983-07-14 1986-05-20 Southern Research Institute Disposable spermicide-releasing diaphragm
US5231112A (en) 1984-04-12 1993-07-27 The Liposome Company, Inc. Compositions containing tris salt of cholesterol hemisuccinate and antifungal
US4895724A (en) 1985-06-07 1990-01-23 Pfizer Inc. Chitosan compositions for controlled and prolonged release of macromolecules
US4795642A (en) 1986-05-01 1989-01-03 Pharmacaps, Inc. Gelatin-encapsulated controlled-release composition
US5208031A (en) 1989-06-06 1993-05-04 Kelly Patrick D Sexual lubricants containing zinc as an anti-viral agent
US5268389A (en) * 1989-10-16 1993-12-07 Uniroyal Chemical Company, Inc. Thiocarboxylate ester compounds compositions containing the same
DE4015543A1 (de) 1990-05-15 1991-11-21 Bayer Ag Spermicides beschichtungsmittel
US5143731A (en) 1990-08-07 1992-09-01 Mediventures Incorporated Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
FR2666587B1 (fr) 1990-09-10 1993-06-25 Dow Corning Sa Compositions de lubrifiant et leur utilisation.
GB9021061D0 (en) 1990-09-27 1990-11-07 Unilever Plc Encapsulating method and products containing encapsulated material
GB9507883D0 (en) * 1995-04-18 1995-05-31 Retroscreen Ltd Compounds
US20020132791A1 (en) * 2000-03-08 2002-09-19 Hildreth James E. Beta-cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
US7713569B2 (en) * 2000-09-01 2010-05-11 Creagri, Inc. Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof
EP1482909B1 (en) * 2002-02-13 2018-07-04 Creagri, Inc. Method and composition for treatment of inflammation
CA2480987C (en) * 2002-04-03 2011-06-14 Puleva Biotech, S.A. Natural products and derivatives thereof for protection against neurodegenerative diseases
JP2004131528A (ja) * 2002-10-08 2004-04-30 Yasushi Okubo 潤滑製剤
JP3799340B2 (ja) * 2003-07-18 2006-07-19 一丸ファルコス株式会社 ヒドロキシチロソール、皮膚外用剤への応用
US20090232748A1 (en) * 2003-11-07 2009-09-17 Viratox, L.L.C. Virucidal activities of cetylpyridinium chloride
US20090163579A1 (en) * 2005-10-14 2009-06-25 Daniel Raederstorff Novel use of nutraceutical compositions
JP2007182398A (ja) * 2006-01-06 2007-07-19 Nakajima Kagaku Sangyo Kk 抗ウィルス性潤滑剤
ES2286953B1 (es) * 2006-05-18 2008-12-16 Universidad De Granada Formulacion de triterpenos naturales y biofenoles obtenidos del genero olea en liposomas.
US20090061031A1 (en) * 2006-07-07 2009-03-05 Sylvia Lee-Huang Compositions and methods for treating obesity, obesity related disorders and for inhibiting the infectivity of human immunodeficiency virus
WO2008148018A2 (en) * 2007-05-24 2008-12-04 New York Blood Center Inc. Rapidly dispersible vaginal tablet that provides a bioadhesive gel
CN101342102A (zh) * 2007-07-10 2009-01-14 赛买提·依明 防早泄的助交避孕套
WO2009109679A1 (es) * 2008-03-04 2009-09-11 Universidad De Granada Uso de compuestos polifenólicos de aceite de oliva virgen en el tratamiento del cáncer
EP2464247B1 (en) * 2009-08-10 2018-05-30 McCord, Darlene Nutritional supplements

Also Published As

Publication number Publication date
US20120260922A1 (en) 2012-10-18
JP2013512275A (ja) 2013-04-11
EP2506841A1 (en) 2012-10-10
KR20120099473A (ko) 2012-09-10
RU2560879C2 (ru) 2015-08-20
AU2010326618A1 (en) 2012-07-19
MX2012006297A (es) 2012-07-23
CN102711745A (zh) 2012-10-03
BR112012013252A2 (pt) 2018-05-29
NZ600912A (en) 2014-05-30
WO2011067302A1 (en) 2011-06-09
CA2782441A1 (en) 2011-06-09
RU2012127436A (ru) 2014-01-20

Similar Documents

Publication Publication Date Title
AP2012006292A0 (en) Topical use of hydroxytyrosol and derivatives for the prevention of HIV infection.
HUS2100027I1 (hu) Tisztított aktív polipeptidek és immunkonjugátumok
HK1216615A1 (zh) 治療或預防大腸桿菌導致的經口感染的組合物和方法
IL216254A (en) Compounds, pharmaceutical compositions and their uses
IL215799A (en) Quinazolone compounds, pharmaceuticals containing them and their uses
MX305105B (es) Tetrahidroazolopirazinas sulfoniladas y su uso como productos medicinales.
AP2011005901A0 (en) Thienopyridine derivatives for the treatment and prevention of dengue virus infections.
FI3494972T3 (fi) Dolutegraviirin ja lamivudiinin yhdistelmiä hiv-infektion hoitoon
IL219325A0 (en) Gadd45beta targeting compounds, compositons comprising the same and uses thereof
WO2011077043A3 (fr) Derives phenoliques, et leur utilisation pharmaceutique ou cosmetique
IL218490A0 (en) Substituted dihydro benzocycloalkyloxymethyl oxazolopyrimidinones, preparation and use thereof
WO2011057262A3 (en) Treatment of infections with tp receptor antagonists
WO2011113060A3 (en) Antiviral compounds and methods of use thereof
BRPI1012155A2 (pt) cateter de segurança.
IL219888A0 (en) Pyridine-pyridinone derivatives, preparation and therapeutic use thereof
ZA201107363B (en) Quinazolinedione derivatives,preparation thereof and various therapeutic uses thereof
IL225724A0 (en) Aceylbenzene history, leases containing them and their uses
IL216828A0 (en) Styryl-triazine derivatives, compositions comprising the same and uses thereof
EP2515903A4 (en) COMPOUNDS, PREPARATION AND USES THEREOF
HK1164861A1 (en) Substituted 3-benzofuranyl-indol-2-one-3-acetamidopiperazine derivatives, preparation thereof, and therapeutic use thereof
ZA201202797B (en) The use of a herbal composition for the treatment of a person infected with hiv
IL213996A0 (en) Sulfamoyl-phenyl-ureido-benzamidine derivatives, compositions comprising the same and uses thereof
AP2011006033A0 (en) Simalikalactone E and use thereof as a medicament.
WO2010109115A9 (fr) Composés anticancéreux, leur préparation et leur application en thérapeutique
SI2421864T1 (sl) 1-pirazolo(4,3-c)izokinolinski derivati, njihova priprava in njihova terapevtska uporaba