AP2008004603A0 - Dibenzyl amine derivatives as CEPT inhibitors - Google Patents
Dibenzyl amine derivatives as CEPT inhibitorsInfo
- Publication number
- AP2008004603A0 AP2008004603A0 AP2008004603A AP2008004603A AP2008004603A0 AP 2008004603 A0 AP2008004603 A0 AP 2008004603A0 AP 2008004603 A AP2008004603 A AP 2008004603A AP 2008004603 A AP2008004603 A AP 2008004603A AP 2008004603 A0 AP2008004603 A0 AP 2008004603A0
- Authority
- AP
- ARIPO
- Prior art keywords
- amine derivatives
- dibenzyl amine
- cept
- inhibitors
- cept inhibitors
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- C07D257/06—Five-membered rings with nitrogen atoms directly attached to the ring carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78148806P | 2006-03-10 | 2006-03-10 | |
US11/619,299 US8383660B2 (en) | 2006-03-10 | 2007-01-03 | Dibenzyl amine compounds and derivatives |
PCT/IB2007/000524 WO2007105049A1 (en) | 2006-03-10 | 2007-02-28 | Dibenzyl amine derivatives as cetp inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
AP2008004603A0 true AP2008004603A0 (en) | 2008-10-31 |
Family
ID=38085975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2008004603A AP2008004603A0 (en) | 2006-03-10 | 2007-02-28 | Dibenzyl amine derivatives as CEPT inhibitors |
Country Status (23)
Country | Link |
---|---|
US (1) | US8383660B2 (es) |
EP (1) | EP1994015B1 (es) |
JP (1) | JP4959731B2 (es) |
KR (1) | KR101059274B1 (es) |
AP (1) | AP2008004603A0 (es) |
AR (1) | AR059802A1 (es) |
AU (1) | AU2007226260B2 (es) |
BR (1) | BRPI0708753A2 (es) |
CA (2) | CA2645291C (es) |
CR (1) | CR10265A (es) |
DK (1) | DK1994015T3 (es) |
DO (1) | DOP2007000044A (es) |
ES (1) | ES2410859T3 (es) |
IL (1) | IL193572A (es) |
MA (1) | MA30272B1 (es) |
MX (1) | MX2008011045A (es) |
NL (1) | NL2000527C2 (es) |
NO (1) | NO20083642L (es) |
PE (1) | PE20071022A1 (es) |
RS (1) | RS20080409A (es) |
TW (1) | TW200736235A (es) |
UY (1) | UY30197A1 (es) |
WO (1) | WO2007105049A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2155666A1 (en) * | 2007-05-10 | 2010-02-24 | Pfizer Limited | Azetidine derivatives and their use as prostaglandin e2 antagonists |
CA2744987C (en) | 2008-12-02 | 2018-01-16 | Chiralgen, Ltd. | Method for the synthesis of phosphorus atom modified nucleic acids |
AU2010270714B2 (en) | 2009-07-06 | 2015-08-13 | Wave Life Sciences Ltd. | Novel nucleic acid prodrugs and methods use thereof |
CN102241667B (zh) | 2010-05-14 | 2013-10-23 | 中国人民解放军军事医学科学院毒物药物研究所 | 1-[(4-羟基哌啶-4基)甲基]吡啶-2(1h)-酮衍生物及其制备方法和用途 |
JP2013538215A (ja) | 2010-08-31 | 2013-10-10 | エスエヌユー アールアンドディービー ファウンデーション | PPARδアゴニストの胎児再プログラミング用途 |
EP2620428B1 (en) * | 2010-09-24 | 2019-05-22 | Wave Life Sciences Ltd. | Asymmetric auxiliary group |
CA2841117A1 (en) | 2011-07-08 | 2013-01-17 | Novartis Ag | 1,2-disubstituted-4-benzylamino-piperidinyl derivatives as cetp inhibitors useful for the treatment of atherosclerosis in high triglyceride subjects |
SG10201700554VA (en) | 2011-07-19 | 2017-03-30 | Wave Life Sciences Pte Ltd | Methods for the synthesis of functionalized nucleic acids |
WO2014012081A2 (en) | 2012-07-13 | 2014-01-16 | Ontorii, Inc. | Chiral control |
SG11201500239VA (en) | 2012-07-13 | 2015-03-30 | Wave Life Sciences Japan | Asymmetric auxiliary group |
BR112015000723A2 (pt) | 2012-07-13 | 2017-06-27 | Shin Nippon Biomedical Laboratories Ltd | adjuvante de ácido nucléico quiral |
CN103351354B (zh) * | 2013-06-09 | 2015-08-12 | 西安近代化学研究所 | 1-甲基-5-氨基四唑合成方法 |
JPWO2015108046A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤 |
US10149905B2 (en) | 2014-01-15 | 2018-12-11 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having antitumor effect and antitumor agent |
EP3095461A4 (en) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator |
MX2016009290A (es) | 2014-01-16 | 2017-02-28 | Wave Life Sciences Ltd | Diseño quiral. |
WO2017030367A1 (ko) * | 2015-08-17 | 2017-02-23 | 인제대학교 산학협력단 | 신규한 이소나이트라민 화합물 및 이를 포함하는 대사성 질환 예방 또는 치료용 조성물 |
US20180244624A1 (en) | 2015-08-17 | 2018-08-30 | Inje University Industry-Academic Cooperation Foundation | Novel isonitramine compound and composition containing same for preventing or treating metabolic diseases |
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US2161938A (en) | 1934-07-31 | 1939-06-13 | Soc Of Chemical Ind | Imidazolines |
US2970082A (en) | 1958-10-07 | 1961-01-31 | Walker Lab Inc | Aluminum nicotinate compositions for hypercholesteremia |
GB984810A (en) | 1961-10-05 | 1965-03-03 | Farmaceutici Italia | Polypeptides |
US3228943A (en) | 1962-06-11 | 1966-01-11 | Lumilysergol derivatives | |
US3338899A (en) | 1962-07-09 | 1967-08-29 | Aron Samuel | 3-phenyl-5-amino-1, 2, 4-oxadiazole compounds |
US3238215A (en) | 1963-10-17 | 1966-03-01 | Sterling Drug Inc | 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines |
NL127065C (es) | 1964-04-22 | |||
FR1460571A (fr) | 1965-06-10 | 1966-03-04 | Innothera Lab Sa | Composés thiényl acétiques et leur préparation |
FR6087M (es) | 1967-01-10 | 1968-06-04 | ||
US3511836A (en) | 1967-12-13 | 1970-05-12 | Pfizer & Co C | 2,4,6,7-tetra substituted quinazolines |
BE729170A (es) | 1968-03-02 | 1969-08-01 | ||
GB1218591A (en) | 1968-04-03 | 1971-01-06 | Delalande Sa | Derivatives of n-(3,4,5-trimethoxy cennamoyl) piperazine and their process of preparation |
CH507249A (de) | 1968-05-31 | 1971-05-15 | Sandoz Ag | Verfahren zur Herstellung von 2-Brom-a-ergokryptin |
FR2092133B1 (es) | 1970-05-06 | 1974-03-22 | Orsymonde | |
GB1435139A (en) | 1972-08-17 | 1976-05-12 | Sumitomo Chemical Co | Thiazole derivatives |
US4146643A (en) | 1973-12-18 | 1979-03-27 | Sandoz Ltd. | Increasing vigilance or treating cerebral insufficiency with substituted vincamines |
NL175059C (nl) | 1974-02-23 | Boehringer Mannheim Gmbh | Bereiding van bloeddrukverlagende stoffen en van preparaten die ze bevatten. | |
DE2733747C2 (de) | 1977-07-27 | 1979-09-27 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von 2,2 Dichlorhydrazobenzol |
US4188390A (en) | 1977-11-05 | 1980-02-12 | Pfizer Inc. | Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines |
IT1094076B (it) | 1978-04-18 | 1985-07-26 | Acraf | Cicloalchiltriazoli |
JPS56110665A (en) | 1980-02-08 | 1981-09-01 | Yamanouchi Pharmaceut Co Ltd | Sulfamoyl-substituted phenetylamine derivative and its preparation |
GB8501372D0 (en) | 1985-01-18 | 1985-02-20 | Smith Kline French Lab | Chemical compounds |
US5061798A (en) | 1985-01-18 | 1991-10-29 | Smith Kline & French Laboratories, Ltd. | Benzyl pyridyl and pyridazinyl compounds |
GB8531071D0 (en) | 1985-12-17 | 1986-01-29 | Boots Co Plc | Therapeutic compound |
US5284971A (en) | 1992-07-16 | 1994-02-08 | Syntex (U.S.A.) Inc. | 4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents |
ATE159515T1 (de) | 1992-07-21 | 1997-11-15 | Ciba Geigy Ag | Oxamidsäure-derivate als hypocholesterämische mittel |
DE4435477A1 (de) | 1994-10-04 | 1996-04-11 | Bayer Ag | Cycloalkano-indol- und -azaindol-derivate |
US5521186A (en) | 1994-10-27 | 1996-05-28 | Janssen Pharmaceutica N.V. | Apolipoprotein-β synthesis inhibitors |
CZ286476B6 (en) | 1994-10-27 | 2000-04-12 | Janssen Pharmaceutica Nv | Heteroaryl substituted derivatives of 1,3-dioxolan-4-ylmethoxyphenyl-1-piperazinylphenyl-2,4-dihydro-2-alkyl-3H-1,2,4-triazol-3-one, process and intermediates for their preparation and pharmaceutical preparations containing thereof |
EP0832069B1 (en) | 1995-06-07 | 2003-03-05 | Pfizer Inc. | BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION |
WO1998023593A1 (en) | 1996-11-27 | 1998-06-04 | Pfizer Inc. | Apo b-secretion/mtp inhibitory amides |
JP2894445B2 (ja) | 1997-02-12 | 1999-05-24 | 日本たばこ産業株式会社 | Cetp活性阻害剤として有効な化合物 |
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EP1737811B1 (en) | 2004-04-13 | 2016-08-10 | Merck Sharp & Dohme Corp. | Cetp inhibitors |
DOP2005000123A (es) | 2004-07-02 | 2011-07-15 | Merck Sharp & Dohme | Inhibidores de cetp |
AU2005308584A1 (en) * | 2004-11-23 | 2006-06-01 | Pfizer Products Inc. | Dibenzyl amine compounds and derivatives |
ES2644450T3 (es) * | 2004-12-31 | 2017-11-29 | Dr. Reddy's Laboratories Ltd. | Nuevos derivados de bencilamina como inhibidores de CETP |
EP1942904A4 (en) * | 2005-09-30 | 2009-11-18 | Merck & Co Inc | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS |
US7919506B2 (en) * | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
-
2007
- 2007-01-03 US US11/619,299 patent/US8383660B2/en not_active Expired - Fee Related
- 2007-02-28 CA CA2645291A patent/CA2645291C/en not_active Expired - Fee Related
- 2007-02-28 KR KR1020087022081A patent/KR101059274B1/ko not_active IP Right Cessation
- 2007-02-28 DK DK07705669.5T patent/DK1994015T3/da active
- 2007-02-28 JP JP2008558923A patent/JP4959731B2/ja not_active Expired - Fee Related
- 2007-02-28 ES ES07705669T patent/ES2410859T3/es active Active
- 2007-02-28 BR BRPI0708753-5A patent/BRPI0708753A2/pt not_active Application Discontinuation
- 2007-02-28 CA CA2717242A patent/CA2717242A1/en not_active Abandoned
- 2007-02-28 MX MX2008011045A patent/MX2008011045A/es active IP Right Grant
- 2007-02-28 AU AU2007226260A patent/AU2007226260B2/en not_active Ceased
- 2007-02-28 RS RSP-2008/0409A patent/RS20080409A/sr unknown
- 2007-02-28 AP AP2008004603A patent/AP2008004603A0/xx unknown
- 2007-02-28 WO PCT/IB2007/000524 patent/WO2007105049A1/en active Application Filing
- 2007-02-28 EP EP07705669.5A patent/EP1994015B1/en active Active
- 2007-03-07 NL NL2000527A patent/NL2000527C2/nl not_active IP Right Cessation
- 2007-03-07 DO DO2007000044A patent/DOP2007000044A/es unknown
- 2007-03-08 UY UY30197A patent/UY30197A1/es not_active Application Discontinuation
- 2007-03-09 PE PE2007000259A patent/PE20071022A1/es not_active Application Discontinuation
- 2007-03-09 TW TW096108178A patent/TW200736235A/zh unknown
- 2007-03-09 AR ARP070100979A patent/AR059802A1/es unknown
-
2008
- 2008-08-20 IL IL193572A patent/IL193572A/en not_active IP Right Cessation
- 2008-08-22 NO NO20083642A patent/NO20083642L/no not_active Application Discontinuation
- 2008-08-29 CR CR10265A patent/CR10265A/es not_active Application Discontinuation
- 2008-09-10 MA MA31226A patent/MA30272B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
US20070213314A1 (en) | 2007-09-13 |
NL2000527A1 (nl) | 2007-09-11 |
BRPI0708753A2 (pt) | 2011-06-28 |
AR059802A1 (es) | 2008-04-30 |
KR20080093156A (ko) | 2008-10-20 |
EP1994015B1 (en) | 2013-04-24 |
RS20080409A (en) | 2009-07-15 |
DK1994015T3 (da) | 2013-06-24 |
CA2645291A1 (en) | 2007-09-20 |
IL193572A (en) | 2013-02-28 |
AU2007226260A1 (en) | 2007-09-20 |
PE20071022A1 (es) | 2007-10-06 |
WO2007105049A1 (en) | 2007-09-20 |
MA30272B1 (fr) | 2009-03-02 |
CA2645291C (en) | 2011-06-28 |
UY30197A1 (es) | 2007-10-31 |
EP1994015A1 (en) | 2008-11-26 |
CR10265A (es) | 2008-09-23 |
JP2009529573A (ja) | 2009-08-20 |
MX2008011045A (es) | 2008-09-08 |
IL193572A0 (en) | 2009-05-04 |
CA2717242A1 (en) | 2007-09-20 |
NL2000527C2 (nl) | 2008-02-06 |
AU2007226260B2 (en) | 2012-02-09 |
NO20083642L (no) | 2008-09-29 |
DOP2007000044A (es) | 2007-09-15 |
TW200736235A (en) | 2007-10-01 |
ES2410859T3 (es) | 2013-07-03 |
KR101059274B1 (ko) | 2011-08-24 |
US8383660B2 (en) | 2013-02-26 |
JP4959731B2 (ja) | 2012-06-27 |
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