AP2000001836A0 - Process for the preparation of paroxetine hydrochloride. - Google Patents

Process for the preparation of paroxetine hydrochloride.

Info

Publication number
AP2000001836A0
AP2000001836A0 APAP/P/2000/001836A AP2000001836A AP2000001836A0 AP 2000001836 A0 AP2000001836 A0 AP 2000001836A0 AP 2000001836 A AP2000001836 A AP 2000001836A AP 2000001836 A0 AP2000001836 A0 AP 2000001836A0
Authority
AP
ARIPO
Prior art keywords
paroxetine hydrochloride
preparation
propan
solution
solvate
Prior art date
Application number
APAP/P/2000/001836A
Other languages
English (en)
Inventor
David Alan Jones
Neal Ward
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of AP2000001836A0 publication Critical patent/AP2000001836A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
APAP/P/2000/001836A 1997-12-19 1998-12-18 Process for the preparation of paroxetine hydrochloride. AP2000001836A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9726907.0A GB9726907D0 (en) 1997-12-19 1997-12-19 Novel compounds
PCT/GB1998/003836 WO1999032484A1 (en) 1997-12-19 1998-12-18 Process for the preparation of paroxetine hydrochloride

Publications (1)

Publication Number Publication Date
AP2000001836A0 true AP2000001836A0 (en) 2000-06-30

Family

ID=10823933

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/2000/001836A AP2000001836A0 (en) 1997-12-19 1998-12-18 Process for the preparation of paroxetine hydrochloride.

Country Status (20)

Country Link
EP (1) EP1042318A1 (id)
JP (1) JP2001526288A (id)
KR (1) KR20010033317A (id)
CN (1) CN1281448A (id)
AP (1) AP2000001836A0 (id)
AU (1) AU1769899A (id)
BG (1) BG104604A (id)
BR (1) BR9813638A (id)
CA (1) CA2315066A1 (id)
EA (1) EA200000689A1 (id)
GB (1) GB9726907D0 (id)
HU (1) HUP0004503A3 (id)
ID (1) ID24733A (id)
IL (1) IL136590A0 (id)
NO (1) NO20003145L (id)
OA (1) OA11635A (id)
PL (1) PL341358A1 (id)
SK (1) SK9242000A3 (id)
TR (1) TR200001933T2 (id)
WO (1) WO1999032484A1 (id)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
NL1017421C2 (nl) 2001-02-21 2002-01-15 Synthon Bv Werkwijze voor het vervaardigen van paroxetine.
AU2002259114A1 (en) * 2002-02-22 2003-09-09 Teva Pharmaceutical Industries Ltd. Preparation of paroxetine involving novel intermediates
KR100672184B1 (ko) 2004-09-21 2007-01-19 주식회사종근당 파록세틴의 콜린산 또는 콜린산 유도체 염

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3688827T2 (de) * 1985-10-25 1994-03-31 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel.
SK283608B6 (sk) * 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie
CA2187128A1 (en) * 1996-10-04 1997-06-26 K. S. Keshava Murthy New and useful polymorph of anhydrous paroxetine hydrochloride

Also Published As

Publication number Publication date
CN1281448A (zh) 2001-01-24
WO1999032484A1 (en) 1999-07-01
EP1042318A1 (en) 2000-10-11
IL136590A0 (en) 2001-06-14
SK9242000A3 (en) 2001-01-18
ID24733A (id) 2000-08-03
TR200001933T2 (tr) 2000-12-21
CA2315066A1 (en) 1999-07-01
PL341358A1 (en) 2001-04-09
OA11635A (en) 2004-11-22
BR9813638A (pt) 2000-10-17
NO20003145D0 (no) 2000-06-16
GB9726907D0 (en) 1998-02-18
HUP0004503A2 (hu) 2002-03-28
JP2001526288A (ja) 2001-12-18
AU1769899A (en) 1999-07-12
BG104604A (en) 2001-03-30
KR20010033317A (ko) 2001-04-25
HUP0004503A3 (en) 2002-04-29
NO20003145L (no) 2000-06-16
EA200000689A1 (ru) 2000-12-25

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