ATE359287T1 - Ein verfahren zur herstellung von clopidogrel - Google Patents

Ein verfahren zur herstellung von clopidogrel

Info

Publication number
ATE359287T1
ATE359287T1 AT03720514T AT03720514T ATE359287T1 AT E359287 T1 ATE359287 T1 AT E359287T1 AT 03720514 T AT03720514 T AT 03720514T AT 03720514 T AT03720514 T AT 03720514T AT E359287 T1 ATE359287 T1 AT E359287T1
Authority
AT
Austria
Prior art keywords
clopidogrel
producing clopidogrel
producing
tetrahydro
meanings
Prior art date
Application number
AT03720514T
Other languages
English (en)
Inventor
Graziano Castaldi
Giuseppe Barreca
Alberto Bologna
Original Assignee
Dipharma Francis Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dipharma Francis Srl filed Critical Dipharma Francis Srl
Application granted granted Critical
Publication of ATE359287T1 publication Critical patent/ATE359287T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/06Peri-condensed systems
AT03720514T 2002-05-03 2003-04-22 Ein verfahren zur herstellung von clopidogrel ATE359287T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002MI000933A ITMI20020933A1 (it) 2002-05-03 2002-05-03 Procedimento per la sintesi di clopidogrel

Publications (1)

Publication Number Publication Date
ATE359287T1 true ATE359287T1 (de) 2007-05-15

Family

ID=11449820

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03720514T ATE359287T1 (de) 2002-05-03 2003-04-22 Ein verfahren zur herstellung von clopidogrel

Country Status (19)

Country Link
US (1) US7329751B2 (de)
EP (1) EP1501838B1 (de)
JP (1) JP2005530757A (de)
KR (1) KR20040106449A (de)
CN (1) CN1293080C (de)
AT (1) ATE359287T1 (de)
AU (1) AU2003224115A1 (de)
CA (1) CA2485070A1 (de)
DE (1) DE60313157T2 (de)
DK (1) DK1501838T3 (de)
EA (1) EA007907B1 (de)
ES (1) ES2285116T3 (de)
HR (1) HRP20041017B1 (de)
IL (1) IL164978A0 (de)
IT (1) ITMI20020933A1 (de)
MX (1) MXPA04010765A (de)
PL (1) PL375213A1 (de)
PT (1) PT1501838E (de)
WO (1) WO2003093276A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100406568C (zh) * 2005-02-18 2008-07-30 淮北市辉克药业有限公司 氯吡格雷新生产工艺
KR100681512B1 (ko) * 2005-03-08 2007-02-09 주식회사 한서켐 클로피도그렐의 신규한 제조 중간체 및 이를 이용한 클로피도그렐의 제조방법
CN100390180C (zh) * 2005-12-15 2008-05-28 上海应用技术学院 氯吡格雷及其盐的制备方法
CN100396687C (zh) * 2006-05-26 2008-06-25 浙江海翔药业股份有限公司 (+)-(s-)-氯吡格雷硫酸氢盐(i型)的制备方法
US20090247569A1 (en) * 2006-08-03 2009-10-01 Claude Singer Process for Preparing Clopidogrel Bisulphate
KR20160033792A (ko) 2007-04-27 2016-03-28 사이덱스 파마슈티칼스, 인크. 클로피도그렐 및 설포알킬 에테르 사이클로덱스트린을 함유하는 제형 및 사용 방법
KR100848936B1 (ko) 2007-05-17 2008-07-29 주식회사 대희화학 클로피도그렐 이성질체의 제조방법 및 이의 제조에사용되는 신규 중간체 화합물
US8236782B2 (en) 2009-05-13 2012-08-07 Cydex Pharmaceuticals, Inc. Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same
CN110527722A (zh) * 2019-09-11 2019-12-03 上海交通大学 一种利用rs2644592和rs11264580检测氯吡格雷药效试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2530247B1 (fr) * 1982-07-13 1986-05-16 Sanofi Sa Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique
FR2664596B1 (fr) * 1990-07-10 1994-06-10 Sanofi Sa Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese.
HU222283B1 (hu) * 1997-05-13 2003-05-28 Sanofi-Synthelabo Eljárás tieno[3,2-c]piridin-származékok előállítására
FR2769313B1 (fr) * 1997-10-06 2000-04-21 Sanofi Sa Derives d'esters hydroxyacetiques, leur procede de preparation et leur utilisation comme intermediaires de synthese

Also Published As

Publication number Publication date
CN1649877A (zh) 2005-08-03
US20050143414A1 (en) 2005-06-30
MXPA04010765A (es) 2005-07-05
DK1501838T3 (da) 2007-08-20
PT1501838E (pt) 2007-06-28
US7329751B2 (en) 2008-02-12
PL375213A1 (en) 2005-11-28
JP2005530757A (ja) 2005-10-13
HRP20041017B1 (en) 2007-08-31
EP1501838A1 (de) 2005-02-02
CA2485070A1 (en) 2003-11-13
CN1293080C (zh) 2007-01-03
WO2003093276A1 (en) 2003-11-13
ITMI20020933A1 (it) 2003-11-03
EA200401234A1 (ru) 2005-06-30
AU2003224115A1 (en) 2003-11-17
ES2285116T3 (es) 2007-11-16
EP1501838B1 (de) 2007-04-11
DE60313157T2 (de) 2007-12-20
EA007907B1 (ru) 2007-02-27
HRP20041017A2 (en) 2004-12-31
DE60313157D1 (de) 2007-05-24
ITMI20020933A0 (it) 2002-05-03
IL164978A0 (en) 2005-12-18
KR20040106449A (ko) 2004-12-17

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