ZA995297B - Polymorph of zopolrestat monohydrate. - Google Patents
Polymorph of zopolrestat monohydrate.Info
- Publication number
- ZA995297B ZA995297B ZA9905297A ZA995297A ZA995297B ZA 995297 B ZA995297 B ZA 995297B ZA 9905297 A ZA9905297 A ZA 9905297A ZA 995297 A ZA995297 A ZA 995297A ZA 995297 B ZA995297 B ZA 995297B
- Authority
- ZA
- South Africa
- Prior art keywords
- polymorph
- zopolrestat monohydrate
- zopolrestat
- monohydrate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9747498P | 1998-08-21 | 1998-08-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA995297B true ZA995297B (en) | 2001-02-19 |
Family
ID=22263562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9905297A ZA995297B (en) | 1998-08-21 | 1999-08-19 | Polymorph of zopolrestat monohydrate. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6159976A (ru) |
| EP (1) | EP0982306A3 (ru) |
| JP (1) | JP2000072769A (ru) |
| KR (1) | KR20000017411A (ru) |
| CN (1) | CN1245804A (ru) |
| AP (1) | AP9901662A0 (ru) |
| AU (1) | AU4453299A (ru) |
| BG (1) | BG103674A (ru) |
| BR (1) | BR9903873A (ru) |
| CA (1) | CA2280590A1 (ru) |
| EA (1) | EA199900675A3 (ru) |
| EE (1) | EE9900385A (ru) |
| GT (1) | GT199900137A (ru) |
| HR (1) | HRP990259A2 (ru) |
| HU (1) | HUP9902783A3 (ru) |
| ID (1) | ID23307A (ru) |
| IL (1) | IL131419A0 (ru) |
| IS (1) | IS5155A (ru) |
| MA (1) | MA26678A1 (ru) |
| NO (1) | NO994027L (ru) |
| NZ (1) | NZ337363A (ru) |
| OA (1) | OA11150A (ru) |
| PA (1) | PA8480601A1 (ru) |
| PE (1) | PE20000993A1 (ru) |
| PL (1) | PL335016A1 (ru) |
| SG (1) | SG83147A1 (ru) |
| TN (1) | TNSN99159A1 (ru) |
| TR (1) | TR199901996A2 (ru) |
| UY (1) | UY25668A1 (ru) |
| YU (1) | YU39899A (ru) |
| ZA (1) | ZA995297B (ru) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3597650T3 (da) | 2010-07-16 | 2022-11-21 | Univ Columbia | Aldosereduktasehæmmere og anvendelser deraf |
| US8916563B2 (en) | 2010-07-16 | 2014-12-23 | The Trustees Of Columbia University In The City Of New York | Aldose reductase inhibitors and uses thereof |
| WO2014126885A1 (en) * | 2013-02-13 | 2014-08-21 | Mylari Banavara L | Water soluble salts of aldose reductase inhibitors for treatment of diabetic complications |
| EP4316603A3 (en) | 2016-06-21 | 2024-04-17 | The Trustees of Columbia University in the City of New York | 4-oxo-3,4-dihydrothieno[3,4-d]pyridazine compounds as aldose reductase inhibitors and methods of use thereof |
| EP4417260A2 (en) | 2017-07-28 | 2024-08-21 | Applied Therapeutics, Inc. | Compositions and methods for treating galactosemia |
| KR20220003529A (ko) | 2019-04-01 | 2022-01-10 | 어플라이드 테라퓨틱스 인크. | 알도스 리덕타제의 억제제 |
| AU2020268368A1 (en) | 2019-05-07 | 2022-01-06 | Ucl Business Ltd | Treatment and detection of inherited neuropathies and associated disorders |
| EP4125909A1 (en) | 2020-03-31 | 2023-02-08 | Applied Therapeutics Inc. | Aldose reductase inhibitors for the treatment of acute respiratory distress syndrome, acute lung inflammation/injury, cardiac injury and anti-viral therapy |
| AU2021264454A1 (en) | 2020-05-01 | 2022-12-08 | Applied Therapeutics, Inc. | Aldose reductase inhibitors for treating sorbitol dehydrogenase deficiency |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4939140A (en) * | 1985-11-07 | 1990-07-03 | Pfizer Inc. | Heterocyclic oxophthalazinyl acetic acids |
| US4748280A (en) * | 1985-11-07 | 1988-05-31 | Pfizer Inc. | Certain chlorination process for preparing 2-chloro-1,1,1-(C1 -C6) |
| US4868301A (en) * | 1987-06-09 | 1989-09-19 | Pfizer Inc. | Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains |
| JPH0676391B2 (ja) * | 1987-06-09 | 1994-09-28 | フアイザー・インコーポレイテツド | ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法 |
| US4904782A (en) * | 1988-02-29 | 1990-02-27 | Pfizer Inc. | Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate |
| US4954629A (en) * | 1989-05-11 | 1990-09-04 | Pfizer Inc. | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof |
| WO1992003432A1 (en) * | 1990-08-28 | 1992-03-05 | Pfizer Inc. | 3-(5-trifluoromethylbenzothiazol-2-ylmethyl)-4-oxo-3h-phythalazin-1-ylacetic acid monohydrate |
| US5391551A (en) * | 1993-05-10 | 1995-02-21 | Pfizer Inc. | Method of lowering blood lipid levels |
| IL120264A0 (en) * | 1996-02-29 | 1997-06-10 | Pfizer | Method of reducing tissue damage associated with non-cardiac ischemia |
-
1999
- 1999-08-06 EP EP99306252A patent/EP0982306A3/en not_active Withdrawn
- 1999-08-13 US US09/374,729 patent/US6159976A/en not_active Expired - Fee Related
- 1999-08-16 IL IL13141999A patent/IL131419A0/xx unknown
- 1999-08-17 IS IS5155A patent/IS5155A/is unknown
- 1999-08-17 AU AU44532/99A patent/AU4453299A/en not_active Abandoned
- 1999-08-18 TN TNTNSN99159A patent/TNSN99159A1/fr unknown
- 1999-08-18 MA MA25738A patent/MA26678A1/fr unknown
- 1999-08-19 OA OA9900185A patent/OA11150A/en unknown
- 1999-08-19 GT GT199900137A patent/GT199900137A/es unknown
- 1999-08-19 EE EEP199900385A patent/EE9900385A/xx unknown
- 1999-08-19 AP APAP/P/1999/001662A patent/AP9901662A0/en unknown
- 1999-08-19 HU HU9902783A patent/HUP9902783A3/hu unknown
- 1999-08-19 UY UY25668A patent/UY25668A1/es not_active Application Discontinuation
- 1999-08-19 ZA ZA9905297A patent/ZA995297B/xx unknown
- 1999-08-19 SG SG9904131A patent/SG83147A1/en unknown
- 1999-08-19 YU YU39899A patent/YU39899A/sh unknown
- 1999-08-19 CA CA002280590A patent/CA2280590A1/en not_active Abandoned
- 1999-08-20 KR KR1019990034527A patent/KR20000017411A/ko not_active Application Discontinuation
- 1999-08-20 PE PE1999000844A patent/PE20000993A1/es not_active Application Discontinuation
- 1999-08-20 BG BG103674A patent/BG103674A/xx unknown
- 1999-08-20 ID IDP990796A patent/ID23307A/id unknown
- 1999-08-20 BR BR9903873-0A patent/BR9903873A/pt not_active Application Discontinuation
- 1999-08-20 NO NO994027A patent/NO994027L/no not_active Application Discontinuation
- 1999-08-20 EA EA199900675A patent/EA199900675A3/ru unknown
- 1999-08-20 PA PA19998480601A patent/PA8480601A1/es unknown
- 1999-08-20 NZ NZ337363A patent/NZ337363A/xx unknown
- 1999-08-20 TR TR1999/01996A patent/TR199901996A2/xx unknown
- 1999-08-20 HR HR990259A patent/HRP990259A2/hr not_active Application Discontinuation
- 1999-08-20 PL PL99335016A patent/PL335016A1/xx not_active Application Discontinuation
- 1999-08-23 CN CN99118068A patent/CN1245804A/zh active Pending
- 1999-08-23 JP JP11235855A patent/JP2000072769A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9902783A3 (en) | 2001-01-29 |
| MA26678A1 (fr) | 2004-12-20 |
| HU9902783D0 (en) | 1999-10-28 |
| AP9901662A0 (en) | 1999-09-30 |
| EE9900385A (et) | 2000-04-17 |
| AU4453299A (en) | 2000-03-09 |
| CN1245804A (zh) | 2000-03-01 |
| NO994027D0 (no) | 1999-08-20 |
| TR199901996A2 (xx) | 2000-03-21 |
| US6159976A (en) | 2000-12-12 |
| GT199900137A (es) | 2001-02-09 |
| HUP9902783A2 (hu) | 2000-12-28 |
| IL131419A0 (en) | 2001-01-28 |
| PL335016A1 (en) | 2000-02-28 |
| EA199900675A2 (ru) | 2000-02-28 |
| NO994027L (no) | 2000-02-22 |
| YU39899A (sh) | 2002-12-10 |
| EA199900675A3 (ru) | 2000-06-26 |
| BR9903873A (pt) | 2000-09-19 |
| SG83147A1 (en) | 2001-09-18 |
| CA2280590A1 (en) | 2000-02-21 |
| NZ337363A (en) | 2001-01-26 |
| EP0982306A3 (en) | 2000-07-05 |
| TNSN99159A1 (fr) | 2005-11-10 |
| HRP990259A2 (en) | 2000-06-30 |
| IS5155A (is) | 2000-02-22 |
| JP2000072769A (ja) | 2000-03-07 |
| PE20000993A1 (es) | 2000-10-04 |
| OA11150A (en) | 2003-04-16 |
| UY25668A1 (es) | 2001-08-27 |
| EP0982306A2 (en) | 2000-03-01 |
| PA8480601A1 (es) | 2000-09-29 |
| BG103674A (en) | 2000-03-31 |
| KR20000017411A (ko) | 2000-03-25 |
| ID23307A (id) | 2000-04-05 |
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