ZA992374B - Catalytic nucleic acid-based diagnostic methods. - Google Patents
Catalytic nucleic acid-based diagnostic methods.Info
- Publication number
- ZA992374B ZA992374B ZA9902374A ZA992374A ZA992374B ZA 992374 B ZA992374 B ZA 992374B ZA 9902374 A ZA9902374 A ZA 9902374A ZA 992374 A ZA992374 A ZA 992374A ZA 992374 B ZA992374 B ZA 992374B
- Authority
- ZA
- South Africa
- Prior art keywords
- nucleic acid
- catalytic nucleic
- diagnostic methods
- based diagnostic
- disorder
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7965198P | 1998-03-27 | 1998-03-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA992374B true ZA992374B (en) | 2000-10-11 |
Family
ID=22151922
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9902374A ZA992374B (en) | 1998-03-27 | 1999-03-26 | Catalytic nucleic acid-based diagnostic methods. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6361941B1 (xx) |
| EP (1) | EP1025266B1 (xx) |
| AT (1) | ATE431852T1 (xx) |
| AU (2) | AU763135B2 (xx) |
| CA (1) | CA2312288A1 (xx) |
| DE (1) | DE69940903D1 (xx) |
| IL (1) | IL136443A (xx) |
| TW (1) | TWI227737B (xx) |
| WO (1) | WO1999050452A1 (xx) |
| ZA (1) | ZA992374B (xx) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7141665B1 (en) * | 1998-04-29 | 2006-11-28 | The Scripps Research Institute | Enzymatic DNA molecules |
| WO2000009673A1 (en) * | 1998-08-13 | 2000-02-24 | Johnson & Johnson Research Pty. Limited | Dnazymes and methods for treating hpv-related disorders |
| CN1323344A (zh) * | 1998-08-13 | 2001-11-21 | 庄臣及庄臣研究股份有限公司 | 治疗再狭窄的DNAzyme和方法 |
| AUPP810399A0 (en) | 1999-01-11 | 1999-02-04 | Unisearch Limited | Catalytic molecules |
| AUPQ201499A0 (en) * | 1999-08-04 | 1999-08-26 | Unisearch Limited | Treatment of inflammatory and malignant diseases |
| US20040009510A1 (en) * | 2000-03-06 | 2004-01-15 | Scott Seiwert | Allosteric nucleic acid sensor molecules |
| AU2002305174A1 (en) * | 2001-04-13 | 2002-10-28 | Johns Hopkins University School Of Medicine | Methods and compositions for identifying disease genes using nonsense-mediated decay inhibition |
| US20050288242A1 (en) * | 2001-05-18 | 2005-12-29 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of RAS gene expression using short interfering nucleic acid (siNA) |
| EP1390472A4 (en) * | 2001-05-29 | 2004-11-17 | Sirna Therapeutics Inc | NUCLEIC ACID TREATMENT OF DISEASES OR SIDES RELATED TO RAS, HER2 AND HIV LEVELS |
| AU2002367785A1 (en) * | 2001-11-05 | 2003-11-03 | Sirna Therapeutics, Inc | Allosteric nucleic acid sensor molecules |
| DE10346487A1 (de) * | 2003-10-02 | 2005-05-12 | Transmit Technologietransfer | Verfahren zur Herstellung eines Zell- und/oder Gewebe- und/oder Krankheitsphasen-spezifischen Arzneimittels |
| WO2005078848A2 (en) * | 2004-02-11 | 2005-08-25 | University Of Tennessee Research Foundation | Inhibition of tumor growth and invasion by anti-matrix metalloproteinase dnazymes |
| WO2005085474A2 (en) * | 2004-03-02 | 2005-09-15 | Clontech Laboratories Inc. | Fluorescent energy transfer labeled nucleic acid substrates and methods of use thereof |
| BRPI0616466B1 (pt) | 2005-10-07 | 2021-01-26 | Johnson & Johnson Research Pty Limited | composição de enzimas de ácido nucleico multicomponentes (mnazima), métodos para detectar a presença de pelo menos um facilitador de combinação, um alvo e uma variante de sequência de ácidos nucléicos, métodos para fabricar uma pluraridade de mnazima, testar sequências de núcleo catalítico parcial e identificar suas posições, bem como uso de pelo menos um oligonucleotídeo |
| DK2066817T3 (da) | 2006-10-06 | 2014-10-13 | Speedx Pty Ltd | Molekylære afbrydere og fremgangsmåder til anvendelse deraf |
| US9938641B2 (en) * | 2006-12-18 | 2018-04-10 | Fluidigm Corporation | Selection of aptamers based on geometry |
| AU2008235256B2 (en) | 2007-04-05 | 2014-05-15 | Speedx Pty Ltd | Nucleic acid enzymes and complexes and methods for their use |
| ES2647237T3 (es) * | 2007-07-03 | 2017-12-20 | Genaphora Ltd. | Cebadores quiméricos para reacciones de amplificación de ácidos nucleicos mejoradas |
| WO2013071163A2 (en) * | 2011-11-11 | 2013-05-16 | Millennium Pharamaceuticals, Inc. | Biomarkers of response to proteasome inhibitors |
| IL304068A (en) | 2020-12-28 | 2023-08-01 | 1E Therapeutics Ltd | DNA enzymes against p21 messenger RNA |
| IL304047A (en) | 2020-12-28 | 2023-08-01 | 1E Therapeutics Ltd | Silencing target sites in the p21 mRNA sequence |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989012697A1 (en) * | 1988-06-22 | 1989-12-28 | The Board Of Regents Of The University Of Washingt | Method for detecting abnormal genes |
| ES2214472T3 (es) * | 1991-08-02 | 2004-09-16 | Biomerieux B.V. | Cuantificacion de acidos nucleicos. |
| US6025127A (en) * | 1994-01-14 | 2000-02-15 | The Johns Hopkins University School Of Medicine | Nucleic acid mutation detection in histologic tissue |
| US5807718A (en) * | 1994-12-02 | 1998-09-15 | The Scripps Research Institute | Enzymatic DNA molecules |
| WO1998012352A1 (en) * | 1996-09-18 | 1998-03-26 | The General Hospital Corporation | Cleaved amplified rflp detection methods |
| US6600030B2 (en) * | 1997-08-14 | 2003-07-29 | The United States Of America As Represented By The Department Of Health And Human Services | Delayed progression to aids by a missense allele of the CCR2 gene |
-
1999
- 1999-03-16 AU AU35303/99A patent/AU763135B2/en not_active Ceased
- 1999-03-16 IL IL13644399A patent/IL136443A/xx not_active IP Right Cessation
- 1999-03-16 AT AT99917023T patent/ATE431852T1/de not_active IP Right Cessation
- 1999-03-16 CA CA002312288A patent/CA2312288A1/en not_active Abandoned
- 1999-03-16 EP EP99917023A patent/EP1025266B1/en not_active Expired - Lifetime
- 1999-03-16 WO PCT/IB1999/000848 patent/WO1999050452A1/en active IP Right Grant
- 1999-03-16 DE DE69940903T patent/DE69940903D1/de not_active Expired - Fee Related
- 1999-03-16 US US09/270,140 patent/US6361941B1/en not_active Expired - Fee Related
- 1999-03-26 ZA ZA9902374A patent/ZA992374B/xx unknown
- 1999-08-31 TW TW088104968A patent/TWI227737B/zh not_active IP Right Cessation
-
2003
- 2003-10-13 AU AU2003252934A patent/AU2003252934A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6361941B1 (en) | 2002-03-26 |
| EP1025266B1 (en) | 2009-05-20 |
| EP1025266A4 (en) | 2002-10-29 |
| WO1999050452A1 (en) | 1999-10-07 |
| EP1025266A1 (en) | 2000-08-09 |
| ATE431852T1 (de) | 2009-06-15 |
| TWI227737B (en) | 2005-02-11 |
| CA2312288A1 (en) | 1999-10-07 |
| IL136443A (en) | 2005-06-19 |
| IL136443A0 (en) | 2001-06-14 |
| AU2003252934A1 (en) | 2003-11-06 |
| DE69940903D1 (de) | 2009-07-02 |
| AU3530399A (en) | 1999-10-18 |
| AU763135B2 (en) | 2003-07-17 |
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