ZA991550B - Cyclohexanediole derivatives. - Google Patents

Cyclohexanediole derivatives.

Info

Publication number
ZA991550B
ZA991550B ZA9901550A ZA991550A ZA991550B ZA 991550 B ZA991550 B ZA 991550B ZA 9901550 A ZA9901550 A ZA 9901550A ZA 991550 A ZA991550 A ZA 991550A ZA 991550 B ZA991550 B ZA 991550B
Authority
ZA
South Africa
Prior art keywords
cyclohexanediole
derivatives
cyclohexanediole derivatives
Prior art date
Application number
ZA9901550A
Other languages
English (en)
Inventor
Pierre Barbier
Franz Bauer
Peter Mohr
Marc Muller
Wolfgang Pirson
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA991550B publication Critical patent/ZA991550B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/02Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
    • C07C47/19Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/263Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups acyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/273Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9901550A 1998-02-26 1999-02-25 Cyclohexanediole derivatives. ZA991550B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98103346 1998-02-26

Publications (1)

Publication Number Publication Date
ZA991550B true ZA991550B (en) 1999-08-26

Family

ID=8231480

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901550A ZA991550B (en) 1998-02-26 1999-02-25 Cyclohexanediole derivatives.

Country Status (21)

Country Link
US (1) US6184422B1 (de)
EP (1) EP1056716B1 (de)
JP (1) JP3507435B2 (de)
KR (1) KR20010041313A (de)
CN (1) CN1133621C (de)
AR (1) AR018120A1 (de)
AT (1) ATE229503T1 (de)
AU (1) AU751241B2 (de)
BR (1) BR9908315A (de)
CA (1) CA2320180C (de)
CO (1) CO4980898A1 (de)
DE (1) DE69904442T2 (de)
DK (1) DK1056716T3 (de)
ES (1) ES2188134T3 (de)
MA (1) MA26609A1 (de)
MY (1) MY133520A (de)
PE (1) PE20000267A1 (de)
PT (1) PT1056716E (de)
TR (1) TR200002477T2 (de)
WO (1) WO1999043646A1 (de)
ZA (1) ZA991550B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0009520A (pt) * 1999-04-01 2002-06-11 Esperion Therapeutics Inc Composto, método para sintetizar o mesmo, composição, metódos para o tratramento ou prevenção, em um paciente, de doença cardiovascular, dislipidemia, dislipoproteinemia, distúrbio de metabolismo de glucose, doença de alzheimer, sìndrome x ou sìndrome metabólica, septicemia, distúrbio trombótico, distúrbio associado com receptor ativado por proliferador de peroxissoma, obesidade, pancreatite, hipertensão, doença renal, câncer, inflamação, impotência, para reduzir o teor de gordura de carne de gado bovino, e, para reduzir o teor de colesterol de ovos de aves
EP1094060B1 (de) * 1999-10-18 2004-04-28 Basilea Pharmaceutica AG Verfahren zur Herstellung von Retiferolderivaten
US6310262B1 (en) 1999-10-18 2001-10-30 Basilea Pharmaceutica Ag Process for preparing retiferol derivatives
WO2002042247A1 (en) * 2000-11-22 2002-05-30 F.Hoffmann-La Roche Ag Retiferol derivatives and their use in the treatment of skin diseases or conditions associated with photodamage
ATE420855T1 (de) * 2001-12-26 2009-01-15 Hiroaki Takayama 2-substituierte vitamin-d-derivate
US6723755B2 (en) 2002-06-12 2004-04-20 Piotr Chomczynski Method of treating rosacea
US7812057B2 (en) * 2004-08-25 2010-10-12 Molecular Research Center, Inc. Cosmetic compositions
ES2533719T3 (es) * 2005-08-30 2015-04-14 Wisconsin Alumni Research Foundation Análogos Des-C,D de 1alfa,25-dihidroxi-19-norvitamina D3
GB0712653D0 (en) 2007-06-28 2007-08-08 Syngenta Ltd Novel herbicides
CA2712748A1 (en) * 2008-01-22 2009-07-30 Wisconsin Alumni Reasearch Foundation 13,13-dimethyl-des-c,d analogs of 1.alpha.,25-dihydroxy-19-nor-vitamin d3 compounds and topical composition dosage forms and methods of treating skin conditions thereof
KR20170096238A (ko) * 2009-01-27 2017-08-23 베르그 엘엘씨 화학요법과 연관된 부작용을 경감시키기 위한 비타민 d3 및 이의 유사물
JP5978130B2 (ja) 2009-08-14 2016-08-24 バーグ エルエルシー 脱毛症を治療するためのビタミンd3およびその類似体
EP3003497B1 (de) 2013-05-29 2024-02-14 BPGbio, Inc. Verhinderung oder verringerung von chemotherapieinduzierter alopezie mit vitamin d
CN114044788A (zh) * 2021-08-12 2022-02-15 甘肃皓天医药科技有限责任公司 一种氟骨化醇cd环的制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2166898C (en) 1993-07-09 2004-09-07 Roger Bouillon Novel structural analogues of vitamin d
PL174912B1 (pl) 1994-01-24 1998-10-30 Inst Farmaceutyczny Nowe związki farmakologicznie czynne z grupy witamin D i sposób ich otrzymywania
US5461116A (en) 1994-11-10 1995-10-24 Shell Oil Company Core functionalized star block copolymers
EP0983221B1 (de) * 1997-05-23 2002-04-03 Basilea Pharmaceutica AG Cyclohexandiolderivate

Also Published As

Publication number Publication date
AU2624699A (en) 1999-09-15
CA2320180A1 (en) 1999-09-02
EP1056716A1 (de) 2000-12-06
ATE229503T1 (de) 2002-12-15
CO4980898A1 (es) 2000-11-27
TR200002477T2 (tr) 2001-03-21
DE69904442D1 (en) 2003-01-23
US6184422B1 (en) 2001-02-06
PT1056716E (pt) 2003-04-30
JP2002504537A (ja) 2002-02-12
CN1133621C (zh) 2004-01-07
DK1056716T3 (da) 2003-04-07
CN1291974A (zh) 2001-04-18
CA2320180C (en) 2005-06-07
BR9908315A (pt) 2000-11-07
MA26609A1 (fr) 2004-12-20
AR018120A1 (es) 2001-10-31
KR20010041313A (ko) 2001-05-15
EP1056716B1 (de) 2002-12-11
MY133520A (en) 2007-11-30
PE20000267A1 (es) 2000-04-10
ES2188134T3 (es) 2003-06-16
JP3507435B2 (ja) 2004-03-15
WO1999043646A1 (en) 1999-09-02
DE69904442T2 (de) 2003-09-25
AU751241B2 (en) 2002-08-08

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