ZA991410B - Compounds and methods for the treatment of bacterial dysentry using antibiotics and toxin binding oligosaccharide compositions. - Google Patents

Compounds and methods for the treatment of bacterial dysentry using antibiotics and toxin binding oligosaccharide compositions.

Info

Publication number
ZA991410B
ZA991410B ZA9901410A ZA991410A ZA991410B ZA 991410 B ZA991410 B ZA 991410B ZA 9901410 A ZA9901410 A ZA 9901410A ZA 991410 A ZA991410 A ZA 991410A ZA 991410 B ZA991410 B ZA 991410B
Authority
ZA
South Africa
Prior art keywords
antibiotics
compounds
treatment
methods
toxin binding
Prior art date
Application number
ZA9901410A
Other languages
English (en)
Inventor
John David Rafter
Robert Murray Ratcliffe
Bradley G Thompson
Glen D Armstrong
Original Assignee
Synsorb Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synsorb Biotech Inc filed Critical Synsorb Biotech Inc
Publication of ZA991410B publication Critical patent/ZA991410B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/52Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA9901410A 1998-02-23 1999-02-22 Compounds and methods for the treatment of bacterial dysentry using antibiotics and toxin binding oligosaccharide compositions. ZA991410B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7564398P 1998-02-23 1998-02-23

Publications (1)

Publication Number Publication Date
ZA991410B true ZA991410B (en) 1999-10-06

Family

ID=22127112

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9901410A ZA991410B (en) 1998-02-23 1999-02-22 Compounds and methods for the treatment of bacterial dysentry using antibiotics and toxin binding oligosaccharide compositions.

Country Status (18)

Country Link
US (2) US6224891B1 (zh)
EP (1) EP1056476A1 (zh)
JP (1) JP2002503708A (zh)
KR (1) KR20010032128A (zh)
CN (1) CN1289254A (zh)
AR (1) AR018104A1 (zh)
AU (1) AU738081B2 (zh)
BR (1) BR9907126A (zh)
CA (1) CA2309943A1 (zh)
DE (1) DE1056476T1 (zh)
ES (1) ES2157872T1 (zh)
GR (1) GR20010300029T1 (zh)
IL (1) IL135976A0 (zh)
NO (1) NO20004193L (zh)
NZ (1) NZ504303A (zh)
PL (1) PL342569A1 (zh)
WO (1) WO1999042136A1 (zh)
ZA (1) ZA991410B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6869602B2 (en) * 2002-02-20 2005-03-22 The United States Of America As Represented By The Secretary Of The Army Method for treating, preventing, or inhibiting enterotoxigenic Escherichia coli infections with bovine red blood cells
US20060051440A1 (en) * 2002-09-10 2006-03-09 Joel Moss Factors that bind intestinal toxins
JP2010505822A (ja) * 2006-10-02 2010-02-25 フリーズランド ブランズ ビー.ブイ. ガラクトオリゴ糖(gos)によるコレラ毒素の抑制
US20100310541A1 (en) * 2007-05-25 2010-12-09 Ironwood Pharmaceuticals, Inc. Compositions and Methods for Reducing the Toxicity of Certain Toxins
GB201402267D0 (en) * 2014-02-10 2014-03-26 Cambridge Entpr Ltd Antibacterial agents
IL271777B2 (en) 2017-07-07 2024-09-01 Epicentrx Inc Preparations for intravenous administration of medical substances
WO2019023320A1 (en) * 2017-07-25 2019-01-31 Arizona Board Of Regents On Behalf Of Arizona State University FAST ANTIBIOTIC SENSITIVITY TESTING BY MONITORING THE SUBMICRON SCALE MOVEMENT OF SIMPLE BACTERIAL CELLS

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1544908A (en) 1975-07-08 1979-04-25 Chembiomed Ltd Artificial oligosaccharide antigenic determinants
US4362720A (en) 1977-04-14 1982-12-07 Chembiomed Ltd. Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals
US5079353A (en) 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
ATE198991T1 (de) * 1991-10-18 2001-02-15 Synsorb Biotech Inc Behandlung bakterieller dysenterie
US5552294A (en) * 1992-10-20 1996-09-03 Children's Medical Center Corporation Rapid detection of virulence-associated factors
US5549895A (en) 1993-05-17 1996-08-27 Iowa State University Research Foundation, Inc. Method and colicin composition for inhibiting Escherichia coli 0157:H7 in food products
FR2747394B1 (fr) 1996-04-15 1998-07-03 Rambach Alain Milieu de culture pour la mise en evidence des bacteries e. coli enterohemorragiques, et procede pour sa mise en evidence
CN1209752A (zh) 1996-06-21 1999-03-03 辛索尔布生物技术有限公司 用于中和大肠杆菌毒素的寡糖的用途
US6063769A (en) 1996-11-14 2000-05-16 Synsorb Biotech, Inc. 1-thiogalactose derivatives
US5910579A (en) 1997-01-10 1999-06-08 Synsorb Biotech Inc. Processes for the preparation of αGal(1->4)βGal (1->4) Glc-OR

Also Published As

Publication number Publication date
CA2309943A1 (en) 1999-08-26
NO20004193D0 (no) 2000-08-22
GR20010300029T1 (en) 2001-08-31
AU738081B2 (en) 2001-09-06
BR9907126A (pt) 2000-10-03
ES2157872T1 (es) 2001-09-01
JP2002503708A (ja) 2002-02-05
IL135976A0 (en) 2001-05-20
KR20010032128A (ko) 2001-04-16
EP1056476A1 (en) 2000-12-06
WO1999042136A1 (en) 1999-08-26
NZ504303A (en) 2002-08-28
US6224891B1 (en) 2001-05-01
CN1289254A (zh) 2001-03-28
AR018104A1 (es) 2001-10-31
NO20004193L (no) 2000-08-22
PL342569A1 (en) 2001-06-18
US20010018065A1 (en) 2001-08-30
AU2606899A (en) 1999-09-06
DE1056476T1 (de) 2001-08-23

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