EP1135144A4 - Compositions and methods for regulating bacterial pathogenesis - Google Patents

Compositions and methods for regulating bacterial pathogenesis

Info

Publication number
EP1135144A4
EP1135144A4 EP99963011A EP99963011A EP1135144A4 EP 1135144 A4 EP1135144 A4 EP 1135144A4 EP 99963011 A EP99963011 A EP 99963011A EP 99963011 A EP99963011 A EP 99963011A EP 1135144 A4 EP1135144 A4 EP 1135144A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
bacterial pathogenesis
regulating bacterial
regulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99963011A
Other languages
German (de)
French (fr)
Other versions
EP1135144A1 (en
Inventor
Bonnie Bassler
Michael G Surette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University Technologies International Inc
Princeton University
Original Assignee
University Technologies International Inc
Princeton University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Technologies International Inc, Princeton University filed Critical University Technologies International Inc
Publication of EP1135144A1 publication Critical patent/EP1135144A1/en
Publication of EP1135144A4 publication Critical patent/EP1135144A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EP99963011A 1998-12-02 1999-12-02 Compositions and methods for regulating bacterial pathogenesis Withdrawn EP1135144A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11057098P 1998-12-02 1998-12-02
US110570P 1998-12-02
PCT/US1999/028751 WO2000032152A2 (en) 1998-12-02 1999-12-02 Compositions and methods for regulating bacterial pathogenesis

Publications (2)

Publication Number Publication Date
EP1135144A1 EP1135144A1 (en) 2001-09-26
EP1135144A4 true EP1135144A4 (en) 2005-07-20

Family

ID=22333745

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99963011A Withdrawn EP1135144A4 (en) 1998-12-02 1999-12-02 Compositions and methods for regulating bacterial pathogenesis

Country Status (6)

Country Link
EP (1) EP1135144A4 (en)
JP (1) JP2003526327A (en)
KR (1) KR20010093800A (en)
AU (1) AU1933800A (en)
CA (1) CA2351731A1 (en)
WO (1) WO2000032152A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7326542B2 (en) * 1998-12-02 2008-02-05 Princeton University Compositions and methods for regulating bacterial pathogenesis
JP2003532698A (en) 2000-05-10 2003-11-05 プリンストン ユニバーシティ Compounds and methods for regulating bacterial growth and pathogenesis
US6416785B1 (en) 2000-08-23 2002-07-09 Biolitec Ag Molecular probes for targeting of cell density-indicating compounds
US7018642B2 (en) 2001-04-27 2006-03-28 The Procter & Gamble Company Compounds, compositions, and methods for controlling biofilms
WO2002094188A2 (en) * 2001-05-21 2002-11-28 Quorex Pharmaceuticals, Inc. Methods for regulating bacteria
WO2003018046A1 (en) 2001-08-24 2003-03-06 Quorex Pharmaceuticals, Inc. Crystals of luxp and complexes thereof
JP2005504777A (en) 2001-08-24 2005-02-17 クオレックス・ファーマシューティカルズ・インコーポレーテッド Antibacterial agents based on oxoanion binding
US20050187190A1 (en) * 2004-01-23 2005-08-25 Sanjay Vasu Autoinducer-2 compounds as immunomodulatory agents
WO2005100384A2 (en) 2004-04-12 2005-10-27 The Trustees Of Princeton University Ai-2 compounds and analogs based on salmonella typhimurium lsrb structure
US7405050B2 (en) 2004-04-12 2008-07-29 The Trustees Of Princeton University Small RNAs and bacterial strains involved in quorum sensing
DE602004027671D1 (en) 2004-09-01 2010-07-22 Hatch Ltd VERBUNDEINBLASROHR
GB0620715D0 (en) 2006-10-18 2006-11-29 Univ Durham Ethanol production
WO2009051232A1 (en) * 2007-10-17 2009-04-23 Kao Corporation Method of determining autoinducer-2
KR101222907B1 (en) 2010-09-08 2013-01-16 고려대학교 산학협력단 DNA chip using random genomic DNA fragments of Yersinia enterocolitica
CN106434843A (en) * 2016-10-27 2017-02-22 江南大学 Culture medium for selectively separating and culturing group B streptococci and preparation method thereof
JP7429799B2 (en) 2020-02-18 2024-02-08 ギリアード サイエンシーズ， インコーポレイテッド antiviral compounds
TWI775313B (en) 2020-02-18 2022-08-21 美商基利科學股份有限公司 Antiviral compounds
TW202322824A (en) 2020-02-18 2023-06-16 美商基利科學股份有限公司 Antiviral compounds
EP4323362A1 (en) 2021-04-16 2024-02-21 Gilead Sciences, Inc. Methods of preparing carbanucleosides using amides
US12116380B2 (en) 2021-08-18 2024-10-15 Gilead Sciences, Inc. Phospholipid compounds and methods of making and using the same
CN117305155B (en) * 2023-08-28 2024-07-05 江苏省家禽科学研究所 Method for inhibiting salmonella virulence factors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9108307D0 (en) * 1991-04-18 1991-06-05 Univ Nottingham Autoinducer
AU2422792A (en) * 1991-07-30 1993-03-02 Bio-Technical Resources Device for detecting aqueous contaminants
FI96697C (en) * 1993-08-18 2001-05-16 Valio Oy New Streptococcus thermophilus strains and their use for antibiotic testing

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HANZELKA B L ET AL: "QUORUM SENSING IN VIBRIO FISCHERI: EVIDENCE THAT S-ADENOSYLMETHIONINE IS THE AMINO ACID SUBSTRATE FOR AUTOINDUCER SYNTHESIS", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, vol. 178, no. 17, September 1996 (1996-09-01), pages 5291 - 5294, XP000857480, ISSN: 0021-9193 *
M. S. SURETTE ET AL: "Quorum sensing in Escherichia coli and Salmonella typhimurium", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, vol. 95, June 1998 (1998-06-01), pages 7046 - 7050, XP002318236 *
See also references of WO0032152A3 *
SURETTE M G ET AL: "Quorum sensing in escherichia coli, Salmonella typhimurium and vibrio harveyi: a new family of genes responsible for autoinducer production", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 96, February 1991 (1991-02-01), pages 1639 - 1644, XP002968927, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
AU1933800A (en) 2000-06-19
CA2351731A1 (en) 2000-06-08
WO2000032152A3 (en) 2002-12-12
EP1135144A1 (en) 2001-09-26
KR20010093800A (en) 2001-10-29
WO2000032152A2 (en) 2000-06-08
JP2003526327A (en) 2003-09-09

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20010627

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RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: UNIVERSITY TECHNOLOGIES INTERNATIONAL

Owner name: PRINCETON UNIVERSITY

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SURETTE, MICHAEL G.

Inventor name: BASSLER, BONNIE, PRINCETON UNIVERSITY

D17D Deferred search report published (deleted)
RIC1 Information provided on ipc code assigned before grant

Ipc: 7G 01N 33/569 B

Ipc: 7G 01N 33/566 B

Ipc: 7G 01N 33/53 B

Ipc: 7C 12N 5/02 B

Ipc: 7C 12N 5/00 B

Ipc: 7A 61K 39/106 A

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