ZA987963B - Disubstituted trans-3,4,4a,5,6,10b-haxahydro-2H-naphth(1,2-b)-1,4-oxazines a process for their preparation and pharmaceutical compositions containing them - Google Patents

Disubstituted trans-3,4,4a,5,6,10b-haxahydro-2H-naphth(1,2-b)-1,4-oxazines a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA987963B
ZA987963B ZA987963A ZA987963A ZA987963B ZA 987963 B ZA987963 B ZA 987963B ZA 987963 A ZA987963 A ZA 987963A ZA 987963 A ZA987963 A ZA 987963A ZA 987963 B ZA987963 B ZA 987963B
Authority
ZA
South Africa
Prior art keywords
oxazines
haxahydro
naphth
preparation
pharmaceutical compositions
Prior art date
Application number
ZA987963A
Other languages
English (en)
Inventor
Jean-Louis Peglion
Jean-Christophe Harmange
Mark Millan
Francoise Lejeune
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA987963B publication Critical patent/ZA987963B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA987963A 1997-09-01 1998-09-01 Disubstituted trans-3,4,4a,5,6,10b-haxahydro-2H-naphth(1,2-b)-1,4-oxazines a process for their preparation and pharmaceutical compositions containing them ZA987963B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9710852A FR2767825A1 (fr) 1997-09-01 1997-09-01 Nouvelles trans-3,4,4a,5,6,10b-hexahydro-2h-napht°1,2-b!-1, 4-oxazines disubstituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA987963B true ZA987963B (en) 1999-03-04

Family

ID=9510643

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA987963A ZA987963B (en) 1997-09-01 1998-09-01 Disubstituted trans-3,4,4a,5,6,10b-haxahydro-2H-naphth(1,2-b)-1,4-oxazines a process for their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US6025356A (de)
EP (1) EP0899267B1 (de)
JP (1) JP4417451B2 (de)
CN (1) CN1088064C (de)
AT (1) ATE229513T1 (de)
AU (1) AU740928C (de)
BR (1) BR9803933A (de)
CA (1) CA2246482C (de)
DE (1) DE69810034T2 (de)
DK (1) DK0899267T3 (de)
ES (1) ES2189108T3 (de)
FR (1) FR2767825A1 (de)
HK (1) HK1020340A1 (de)
HU (1) HU226059B1 (de)
NO (1) NO311218B1 (de)
NZ (1) NZ331637A (de)
PL (1) PL194533B1 (de)
PT (1) PT899267E (de)
ZA (1) ZA987963B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130219D0 (en) * 2001-12-18 2002-02-06 Pfizer Ltd Compounds for the treatment of sexual dysfunction
WO2004019889A2 (en) * 2002-08-30 2004-03-11 Biostratum, Inc. Inhibitors of post-amadori advanced glycation end products
BRPI0409492A (pt) * 2003-04-18 2006-05-02 Pharmacia & Up John Company Ll terapias de combinação
FR2906249B1 (fr) * 2006-09-26 2008-12-19 Servier Lab Composes tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2098511A1 (de) 2008-03-07 2009-09-09 Solvias AG Verfahren zur Herstellung von Verbindungen mit einer Hydronaphtalinstruktur mit einem asymmetrisch substituierten Benzolring
JP2011525893A (ja) * 2008-06-27 2011-09-29 ハー・ルンドベック・アクチエゼルスカベット 新規のフェノールアミン類およびカテコールアミン類ならびにそのプロドラッグ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420480A (en) * 1981-11-20 1983-12-13 Merck & Co., Inc. Hexahydronaphth[1,2-b]-1,4-oxazines
CA1204745A (en) * 1981-11-20 1986-05-20 Merck Co. Hexahydronaphth (1,2-b) -1,4 -oxazines
US4540691A (en) * 1984-04-13 1985-09-10 Nelson Research & Development Co. Dopamine agonists and use thereof
US5486611A (en) * 1989-07-13 1996-01-23 The Upjohn Company Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives
JPH05508408A (ja) * 1990-06-15 1993-11-25 ホイツトビー・リサーチ・インコーポレーテツド ドーパミン作動性薬剤として有用な置換ナフトキサジン類

Also Published As

Publication number Publication date
DE69810034D1 (de) 2003-01-23
AU740928C (en) 2002-05-16
PL328285A1 (en) 1999-03-15
AU8302498A (en) 1999-03-11
NO311218B1 (no) 2001-10-29
PL194533B1 (pl) 2007-06-29
HUP9801951A3 (en) 2000-04-28
FR2767825A1 (fr) 1999-02-26
CA2246482A1 (fr) 1999-03-01
HK1020340A1 (en) 2000-04-14
JP4417451B2 (ja) 2010-02-17
AU740928B2 (en) 2001-11-15
NZ331637A (en) 1999-07-29
NO984007D0 (no) 1998-08-31
CN1222516A (zh) 1999-07-14
DE69810034T2 (de) 2003-08-14
PT899267E (pt) 2003-04-30
BR9803933A (pt) 2001-04-24
JPH11130759A (ja) 1999-05-18
HU9801951D0 (en) 1998-11-30
ES2189108T3 (es) 2003-07-01
CN1088064C (zh) 2002-07-24
HU226059B1 (en) 2008-04-28
HUP9801951A2 (hu) 2000-02-28
NO984007L (no) 1999-03-02
EP0899267B1 (de) 2002-12-11
ATE229513T1 (de) 2002-12-15
EP0899267A1 (de) 1999-03-03
DK0899267T3 (da) 2003-03-10
CA2246482C (fr) 2002-11-26
US6025356A (en) 2000-02-15

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