ZA987819B - Novel specific immunophilin ligands as antiasthmatics antiallergics antirheumatics immunosuppressants antipsorlatics and neuroprotectants - Google Patents
Novel specific immunophilin ligands as antiasthmatics antiallergics antirheumatics immunosuppressants antipsorlatics and neuroprotectantsInfo
- Publication number
- ZA987819B ZA987819B ZA987819A ZA987819A ZA987819B ZA 987819 B ZA987819 B ZA 987819B ZA 987819 A ZA987819 A ZA 987819A ZA 987819 A ZA987819 A ZA 987819A ZA 987819 B ZA987819 B ZA 987819B
- Authority
- ZA
- South Africa
- Prior art keywords
- antipsorlatics
- neuroprotectants
- antirheumatics
- antiasthmatics
- antiallergics
- Prior art date
Links
- 229940123907 Disease modifying antirheumatic drug Drugs 0.000 title 1
- 102000000521 Immunophilins Human genes 0.000 title 1
- 108010016648 Immunophilins Proteins 0.000 title 1
- 230000003266 anti-allergic effect Effects 0.000 title 1
- 230000001088 anti-asthma Effects 0.000 title 1
- 230000003356 anti-rheumatic effect Effects 0.000 title 1
- 239000000043 antiallergic agent Substances 0.000 title 1
- 239000000924 antiasthmatic agent Substances 0.000 title 1
- 239000003435 antirheumatic agent Substances 0.000 title 1
- 229960003444 immunosuppressant agent Drugs 0.000 title 1
- 239000003018 immunosuppressive agent Substances 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 239000004090 neuroprotective agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19742263A DE19742263A1 (de) | 1997-09-25 | 1997-09-25 | Neue spezifische Immunophilin-Liganden als Antiasthmatika, Antiallergika, Antirheumatika, Immunsuppressiva, Antipsoriatika, Neuroprotektiva |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA987819B true ZA987819B (en) | 1999-04-07 |
Family
ID=7843549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA987819A ZA987819B (en) | 1997-09-25 | 1998-08-27 | Novel specific immunophilin ligands as antiasthmatics antiallergics antirheumatics immunosuppressants antipsorlatics and neuroprotectants |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1017673A1 (xx) |
| JP (1) | JP2001517653A (xx) |
| KR (1) | KR20010040253A (xx) |
| AU (1) | AU9345098A (xx) |
| BR (1) | BR9813226A (xx) |
| CA (1) | CA2304451A1 (xx) |
| DE (1) | DE19742263A1 (xx) |
| HU (1) | HUP0004294A3 (xx) |
| IL (1) | IL133246A0 (xx) |
| NO (1) | NO20001510L (xx) |
| WO (1) | WO1999015501A1 (xx) |
| ZA (1) | ZA987819B (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1084106A1 (en) | 1998-06-03 | 2001-03-21 | GPI NIL Holdings, Inc. | N-linked sulfonamides of heterocyclic carboxylic acids or carboxylic acid isosteres |
| US6300341B1 (en) | 1998-09-30 | 2001-10-09 | The Procter & Gamble Co. | 2-substituted heterocyclic sulfonamides |
| US6417189B1 (en) | 1999-11-12 | 2002-07-09 | Gpi Nil Holdings, Inc. | AZA compounds, pharmaceutical compositions and methods of use |
| US7253169B2 (en) | 1999-11-12 | 2007-08-07 | Gliamed, Inc. | Aza compounds, pharmaceutical compositions and methods of use |
| WO2001046195A1 (en) | 1999-12-21 | 2001-06-28 | Gpi Nil Holdings, Inc. | Hydantoin derivative compounds, pharmaceutical compositions, and methods of using same |
| RU2252760C1 (ru) * | 2003-12-08 | 2005-05-27 | Лимонов Виктор Львович | Средство для лечения аутоиммунных заболеваний |
| KR20070029809A (ko) * | 2004-06-18 | 2007-03-14 | 바이올리폭스 에이비 | 염증치료에 유용한 인돌 |
| BRPI0512252A (pt) | 2004-06-18 | 2008-02-19 | Biolipox Ab | composto ou um sal farmaceuticamente aceitável do mesmo, formulação farmacêutica, uso de um composto, método de tratamento de uma doença, produto combinado, e, processo para a preparação de um composto |
| WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
| CA2593155A1 (en) | 2005-01-19 | 2006-07-27 | Biolipox Ab | Indoles useful in the treatment of inflammation |
| WO2013138600A1 (en) * | 2012-03-16 | 2013-09-19 | Rosen Eliot M | Radioprotector compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192773A (en) * | 1990-07-02 | 1993-03-09 | Vertex Pharmaceuticals, Inc. | Immunosuppressive compounds |
| MX9202466A (es) * | 1991-05-24 | 1994-06-30 | Vertex Pharma | Compuestos inmunosupresores novedosos. |
| US5385918A (en) * | 1993-02-09 | 1995-01-31 | Miles Inc. | Aminomethylene-peptides as immunosuppressants |
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| US5614547A (en) * | 1995-06-07 | 1997-03-25 | Guilford Pharmaceuticals Inc. | Small molecule inhibitors of rotamase enzyme |
| US5795890A (en) * | 1995-09-27 | 1998-08-18 | Ono Pharmaceutical Co., Ltd. | Sulfonamide derivatives |
| DE19542189A1 (de) * | 1995-11-13 | 1997-05-15 | Hoechst Ag | Cyclische N-substituierte alpha-Iminohydroxamsäuren |
| DE19616509A1 (de) * | 1996-04-25 | 1998-01-15 | Asta Medica Ag | Neue spezifische Immunophilin-Liganden als Antiasthmatika, Immunsuppressiva |
-
1997
- 1997-09-25 DE DE19742263A patent/DE19742263A1/de not_active Withdrawn
-
1998
- 1998-08-20 IL IL13324698A patent/IL133246A0/xx unknown
- 1998-08-20 BR BR9813226-1A patent/BR9813226A/pt not_active IP Right Cessation
- 1998-08-20 HU HU0004294A patent/HUP0004294A3/hu unknown
- 1998-08-20 CA CA002304451A patent/CA2304451A1/en not_active Abandoned
- 1998-08-20 WO PCT/EP1998/005300 patent/WO1999015501A1/de not_active Ceased
- 1998-08-20 JP JP2000512810A patent/JP2001517653A/ja active Pending
- 1998-08-20 EP EP98946392A patent/EP1017673A1/de not_active Withdrawn
- 1998-08-20 KR KR1020007003191A patent/KR20010040253A/ko not_active Withdrawn
- 1998-08-20 AU AU93450/98A patent/AU9345098A/en not_active Abandoned
- 1998-08-27 ZA ZA987819A patent/ZA987819B/xx unknown
-
2000
- 2000-03-23 NO NO20001510A patent/NO20001510L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999015501A1 (de) | 1999-04-01 |
| HUP0004294A3 (en) | 2001-11-28 |
| AU9345098A (en) | 1999-04-12 |
| KR20010040253A (ko) | 2001-05-15 |
| IL133246A0 (en) | 2001-04-30 |
| NO20001510L (no) | 2000-05-22 |
| DE19742263A1 (de) | 1999-04-01 |
| EP1017673A1 (de) | 2000-07-12 |
| HUP0004294A2 (hu) | 2001-05-28 |
| JP2001517653A (ja) | 2001-10-09 |
| NO20001510D0 (no) | 2000-03-23 |
| BR9813226A (pt) | 2000-08-29 |
| CA2304451A1 (en) | 1999-04-01 |
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