ZA987660B - Novel tissue-specific calpains, their preparation and use. - Google Patents

Novel tissue-specific calpains, their preparation and use.

Info

Publication number
ZA987660B
ZA987660B ZA9807660A ZA987660A ZA987660B ZA 987660 B ZA987660 B ZA 987660B ZA 9807660 A ZA9807660 A ZA 9807660A ZA 987660 A ZA987660 A ZA 987660A ZA 987660 B ZA987660 B ZA 987660B
Authority
ZA
South Africa
Prior art keywords
preparation
novel tissue
calpains
specific
specific calpains
Prior art date
Application number
ZA9807660A
Other languages
English (en)
Inventor
Thomas Boehm
Neil T Dear
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ZA987660B publication Critical patent/ZA987660B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96466—Cysteine endopeptidases (3.4.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
ZA9807660A 1997-08-26 1998-08-25 Novel tissue-specific calpains, their preparation and use. ZA987660B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19737105A DE19737105A1 (de) 1997-08-26 1997-08-26 Neue gewebsspezifische Calpaine, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ZA987660B true ZA987660B (en) 2000-02-25

Family

ID=7840195

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9807660A ZA987660B (en) 1997-08-26 1998-08-25 Novel tissue-specific calpains, their preparation and use.

Country Status (13)

Country Link
EP (1) EP1009811A2 (de)
JP (1) JP2001513992A (de)
KR (1) KR20010023282A (de)
CN (1) CN1277634A (de)
AU (1) AU9263598A (de)
BR (1) BR9811365A (de)
CA (1) CA2301815A1 (de)
DE (1) DE19737105A1 (de)
HU (1) HUP0004027A2 (de)
IL (1) IL134361A0 (de)
NO (1) NO20000961L (de)
WO (1) WO1999010480A2 (de)
ZA (1) ZA987660B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19928021A1 (de) * 1999-06-18 2000-12-21 Basf Ag Neue Calpaine und deren Verwendung
WO2001018216A2 (en) * 1999-09-09 2001-03-15 Millennium Pharmaceuticals, Inc. 26176, a novel calpain protease and uses thereof
AU4422401A (en) * 2000-03-28 2001-10-08 Bayer Aktiengesellschaft Regulation of human neutral protease-related enzyme
AUPQ656500A0 (en) * 2000-03-28 2000-04-20 Autogen Pty Ltd A method of treatment and agents for same
WO2002081684A2 (en) * 2001-04-04 2002-10-17 Universite De Montreal Antisense calpain nucleotides and uses thereof
JP4593404B2 (ja) * 2005-08-29 2010-12-08 シスメックス株式会社 液体試料吸引監視方法及び装置、並びに液体試料分析装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996002634A1 (en) * 1994-07-15 1996-02-01 Cephalon, Inc. Active calpain expressed by baculovirus
EP0799892A3 (de) * 1996-04-05 1998-08-12 Takeda Chemical Industries, Ltd. Calpain, seine Herstellung und Verwendung

Also Published As

Publication number Publication date
HUP0004027A2 (en) 2001-03-28
CA2301815A1 (en) 1999-03-04
CN1277634A (zh) 2000-12-20
DE19737105A1 (de) 1999-03-04
JP2001513992A (ja) 2001-09-11
WO1999010480A2 (de) 1999-03-04
NO20000961D0 (no) 2000-02-25
BR9811365A (pt) 2000-08-22
EP1009811A2 (de) 2000-06-21
KR20010023282A (ko) 2001-03-26
NO20000961L (no) 2000-04-14
WO1999010480A3 (de) 1999-05-27
IL134361A0 (en) 2001-04-30
AU9263598A (en) 1999-03-16

Similar Documents

Publication Publication Date Title
ZA972727B (en) A novel composition, its preparation and use.
HK1078561A1 (en) Novel compounds, their use and preparation
HK1018780A1 (en) 6-Phenylpyridine-2-ylamine derivatives, the composition and use thereof.
ZA975013B (en) Modified factor VII.
ZA9710429B (en) Broad-spectrumδ-endotoxins.
ZA976168B (en) 3-Ureido-pyridofurans and -pyridothiophenes.
HK1019774A1 (en) Etching composition and use thereof.
ZA983148B (en) Modified TNFÓ, DNA encoding such modified TNFÓ and vacines comprising said TNFÓ and DNA.
ZA964711B (en) Novel compounds, the preparation and use thereof.
ZA977206B (en) Arylalkanoylpyridazines.
HK1005962A1 (en) Alkaline cell and the preparation thereof.
ZA986421B (en) 2-[Pyrazolyl-and triazolyl-3'-oxymethylene]phenylisoxa zolones, -triazolones and - tetrazolones, their preparation and their use.
ZA991845B (en) Catalyst and use thereof.
EP0665277A3 (de) Wasserabweisende Mittel, deren Herstellung und deren Anwendung.
EP0671470A3 (de) Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung.
ZA969402B (en) Novel oligopeptides, the preparation and use thereof.
ZA9810625B (en) Benzylidenepyrazolones, their preparation and use.
ZA987660B (en) Novel tissue-specific calpains, their preparation and use.
ZA97572B (en) 1-pyrazol-3-ylethyl-4-indol-3-ylpiperidines.
AU5557698A (en) Novel calpaines, their preparation and use
ZA963620B (en) (Het)aryloxy-, -thio- and -aminocrotonates, their preparation and their use.
HK1039339A1 (en) Outer surface proteins, their genes, and their use.
ZA976022B (en) Cycloalkano-pyridines.
ZA997637B (en) Substituted cycloheptenes, their preparation and use.
ZA971466B (en) Endothelin-receptor-antagonists.