ZA986636B - A pharmaceutical composition active in reducing production of MCP-1 protein - Google Patents
A pharmaceutical composition active in reducing production of MCP-1 proteinInfo
- Publication number
- ZA986636B ZA986636B ZA986636A ZA986636A ZA986636B ZA 986636 B ZA986636 B ZA 986636B ZA 986636 A ZA986636 A ZA 986636A ZA 986636 A ZA986636 A ZA 986636A ZA 986636 B ZA986636 B ZA 986636B
- Authority
- ZA
- South Africa
- Prior art keywords
- mcp
- protein
- pharmaceutical composition
- reducing production
- composition active
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Surgery (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT97MI001789A IT1293795B1 (it) | 1997-07-28 | 1997-07-28 | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA986636B true ZA986636B (en) | 1999-02-04 |
Family
ID=11377642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA986636A ZA986636B (en) | 1997-07-28 | 1998-07-24 | A pharmaceutical composition active in reducing production of MCP-1 protein |
Country Status (16)
Country | Link |
---|---|
US (1) | US6534534B1 (ja) |
EP (1) | EP1005332B1 (ja) |
JP (2) | JP4651191B2 (ja) |
AR (1) | AR016382A1 (ja) |
AT (1) | ATE251902T1 (ja) |
AU (1) | AU744492B2 (ja) |
CA (1) | CA2300289C (ja) |
DE (1) | DE69819012T2 (ja) |
DK (1) | DK1005332T3 (ja) |
ES (1) | ES2207858T3 (ja) |
HK (1) | HK1028561A1 (ja) |
IT (1) | IT1293795B1 (ja) |
PT (1) | PT1005332E (ja) |
SI (1) | SI1005332T1 (ja) |
WO (1) | WO1999004770A2 (ja) |
ZA (1) | ZA986636B (ja) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1293795B1 (it) * | 1997-07-28 | 1999-03-10 | Angelini Ricerche Spa | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
ITMI20062254A1 (it) | 2006-11-24 | 2008-05-25 | Acraf | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
AU2009221089B2 (en) | 2008-03-07 | 2013-12-05 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | Novel 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40 |
KR101581829B1 (ko) * | 2008-03-07 | 2015-12-31 | 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 | 1-벤질-3-하이드록시메틸인다졸 유도체들 및 mcp-1 및 cx3cr1의 발현을 기초로 한 질환들의 치료에서 이의 용도 |
LT2262778T (lt) | 2008-03-07 | 2019-11-11 | Acraf | 1-benzil-3-hidroksimetilindazolo dariniai ir jų panaudojimas gydant ligas, pagrįstas mcp-1, cxcr1 ir p40 raiška |
CN106518769A (zh) | 2009-08-03 | 2017-03-22 | 方济各安吉利克化学联合股份有限公司 | 1‑苄基‑3‑羟甲基‑1h‑吲唑及其衍生物以及所需镁中间体的制备方法 |
UA108742C2 (uk) * | 2009-09-23 | 2015-06-10 | Фармацевтична композиція для лікування запальних захворювань, опосередкованих mcp-1 | |
GB2550526B (en) | 2010-02-25 | 2018-02-07 | Prairie Ventures Llc | System and method for anatomical pathology sample handling, storage, and analysis |
US8999292B2 (en) | 2012-05-01 | 2015-04-07 | Translatum Medicus Inc. | Methods for treating and diagnosing blinding eye diseases |
WO2016201426A1 (en) | 2015-06-12 | 2016-12-15 | Vettore, LLC | Mct4 inhibitors for treating disease |
JP7123929B2 (ja) | 2016-12-12 | 2022-08-23 | ベットーレ リミテッド ライアビリティー カンパニー | Mct4の複素環阻害剤 |
US11753382B2 (en) | 2019-06-25 | 2023-09-12 | Translatum Medicus Inc. | Processes of making 2-((1-benzyl-1H-indazol-3-yl)methoxy)-2-methylpropanoic acid and its derivatives |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1230441B (it) * | 1989-02-07 | 1991-10-23 | Acraf | Eteri della serie dell'indazolo |
US5100899A (en) * | 1989-06-06 | 1992-03-31 | Roy Calne | Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof |
IT1253703B (it) | 1991-04-22 | 1995-08-23 | Angelini Francesco Ist Ricerca | Uso di acidi metossi alcanoici dell'indazolo per preparare un farmaco attivo nel trattamento di malattie autoimmunitarie |
WO1994009128A1 (en) | 1992-10-22 | 1994-04-28 | Mallinckrodt Medical, Inc. | Therapeutic treatment for inhibiting vascular restenosis |
US5563145A (en) * | 1994-12-07 | 1996-10-08 | American Home Products Corporation | Rapamycin 42-oximes and hydroxylamines |
JPH08333262A (ja) * | 1995-04-07 | 1996-12-17 | Chugai Pharmaceut Co Ltd | 免疫抑制剤 |
US6113898A (en) * | 1995-06-07 | 2000-09-05 | Idec Pharmaceuticals Corporation | Human B7.1-specific primatized antibodies and transfectomas expressing said antibodies |
DE19538402A1 (de) * | 1995-10-14 | 1997-04-17 | Boehringer Mannheim Gmbh | Lipidalkohole als neue immunsuppressive und antivirale Arzneimittel |
JPH09165339A (ja) * | 1995-10-27 | 1997-06-24 | American Home Prod Corp | ラパマイシンを付与したドナー脾細胞を用いる臓器移植の延長 |
IT1276031B1 (it) * | 1995-10-31 | 1997-10-24 | Angelini Ricerche Spa | Composizione farmaceutica per il trattamento delle malattie autoimmuni |
US5780462A (en) * | 1995-12-27 | 1998-07-14 | American Home Products Corporation | Water soluble rapamycin esters |
IT1293795B1 (it) * | 1997-07-28 | 1999-03-10 | Angelini Ricerche Spa | Farmaco attivo nel ridurre la produzione di proteina mcp-1 |
-
1997
- 1997-07-28 IT IT97MI001789A patent/IT1293795B1/it active IP Right Grant
-
1998
- 1998-07-22 JP JP2000503829A patent/JP4651191B2/ja not_active Expired - Fee Related
- 1998-07-22 DE DE69819012T patent/DE69819012T2/de not_active Expired - Lifetime
- 1998-07-22 SI SI9830573T patent/SI1005332T1/xx unknown
- 1998-07-22 DK DK98943862T patent/DK1005332T3/da active
- 1998-07-22 PT PT98943862T patent/PT1005332E/pt unknown
- 1998-07-22 ES ES98943862T patent/ES2207858T3/es not_active Expired - Lifetime
- 1998-07-22 AT AT98943862T patent/ATE251902T1/de active
- 1998-07-22 EP EP98943862A patent/EP1005332B1/en not_active Expired - Lifetime
- 1998-07-22 CA CA002300289A patent/CA2300289C/en not_active Expired - Fee Related
- 1998-07-22 WO PCT/EP1998/004924 patent/WO1999004770A2/en active IP Right Grant
- 1998-07-22 US US09/463,666 patent/US6534534B1/en not_active Expired - Lifetime
- 1998-07-22 AU AU91601/98A patent/AU744492B2/en not_active Ceased
- 1998-07-24 ZA ZA986636A patent/ZA986636B/xx unknown
- 1998-07-28 AR ARP980103695A patent/AR016382A1/es unknown
-
2000
- 2000-12-07 HK HK00107851A patent/HK1028561A1/xx not_active IP Right Cessation
-
2009
- 2009-11-09 JP JP2009270715A patent/JP5086322B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU744492B2 (en) | 2002-02-28 |
WO1999004770A2 (en) | 1999-02-04 |
ITMI971789A1 (it) | 1999-01-28 |
AU9160198A (en) | 1999-02-16 |
DK1005332T3 (da) | 2004-02-09 |
DE69819012D1 (de) | 2003-11-20 |
CA2300289A1 (en) | 1999-02-04 |
JP2001510793A (ja) | 2001-08-07 |
JP2010047609A (ja) | 2010-03-04 |
IT1293795B1 (it) | 1999-03-10 |
EP1005332B1 (en) | 2003-10-15 |
US6534534B1 (en) | 2003-03-18 |
WO1999004770A3 (en) | 1999-04-15 |
ES2207858T3 (es) | 2004-06-01 |
ATE251902T1 (de) | 2003-11-15 |
JP4651191B2 (ja) | 2011-03-16 |
CA2300289C (en) | 2007-11-20 |
SI1005332T1 (en) | 2004-02-29 |
PT1005332E (pt) | 2004-03-31 |
DE69819012T2 (de) | 2004-08-12 |
HK1028561A1 (en) | 2001-02-23 |
AR016382A1 (es) | 2001-07-04 |
JP5086322B2 (ja) | 2012-11-28 |
EP1005332A2 (en) | 2000-06-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUP0103616A3 (en) | Therapeutically active proteins in plants | |
HUP0100178A3 (en) | Tetrahydro-naphtiridinyl-imidazolydinyl-carboxylic acid derivatives and pharmaceutical compositions thereof | |
IL123986A0 (en) | Antithombotic agents process for their preparation and pharmaceutical compositions comprising them | |
HUP0000737A3 (en) | Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid | |
HUP9601698A3 (en) | Pharmaceutical composition of adiabetical activity | |
HK1061841A1 (en) | Cyclic amino acids and derivatives thereof useful as pharmaceutical agents | |
HU9502918D0 (en) | Pharmaceutical composition of antihypertriglyceridemic activity | |
ZA986636B (en) | A pharmaceutical composition active in reducing production of MCP-1 protein | |
ZA984266B (en) | Pharmaceutical composition and process of preparation | |
HUP0003189A2 (en) | Pharmaceutical composition comprising fexofenadine and its derivatives | |
ZA983239B (en) | Stable active human ob protein compositions and methods | |
HU9802716D0 (en) | Pharmaceutical composition of analgesic activity | |
IL134050A0 (en) | A pharmaceutical composition active in reducing production of mcp-1 protein | |
PL337807A1 (en) | Sertralin dosage formulation in the form of a gelatine-encapsulated solution | |
AU5337198A (en) | Production of biologically active polypeptides | |
ZA9811105B (en) | Cosmetic and pharmaceutical composition | |
ZA9810846B (en) | An active hedgehog-protein-mutant a process for its preparation and its use for pharmaceutical purposes | |
HU9702369D0 (en) | Pharmaceutical composition of natural active components | |
GB9711697D0 (en) | Biologically and therapeutically active agents | |
GB9915380D0 (en) | Biologically and therapeutically active agents | |
GB9814238D0 (en) | Biologically and therapeutically active agents | |
GB9720963D0 (en) | Pharmaceutical compositions and method of production | |
GB9409478D0 (en) | Biologically and therapeutically active agents | |
GB9408684D0 (en) | Biologically and therapeutically active agents | |
GB9511773D0 (en) | Biologically and therapeutically active agents |