ZA983350B - Vitamin D3 analogs with bis c-20 side chains - Google Patents

Vitamin D3 analogs with bis c-20 side chains

Info

Publication number
ZA983350B
ZA983350B ZA983350A ZA983350A ZA983350B ZA 983350 B ZA983350 B ZA 983350B ZA 983350 A ZA983350 A ZA 983350A ZA 983350 A ZA983350 A ZA 983350A ZA 983350 B ZA983350 B ZA 983350B
Authority
ZA
South Africa
Prior art keywords
analogs
vitamin
bis
side chains
chains
Prior art date
Application number
ZA983350A
Other languages
English (en)
Inventor
Percy Sarwood Manchand
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA983350B publication Critical patent/ZA983350B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/21—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA983350A 1997-04-28 1998-04-21 Vitamin D3 analogs with bis c-20 side chains ZA983350B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4466197P 1997-04-28 1997-04-28

Publications (1)

Publication Number Publication Date
ZA983350B true ZA983350B (en) 1998-10-28

Family

ID=21933610

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA983350A ZA983350B (en) 1997-04-28 1998-04-21 Vitamin D3 analogs with bis c-20 side chains

Country Status (6)

Country Link
US (1) US6030962A (es)
AR (1) AR012598A1 (es)
CO (1) CO4940443A1 (es)
HR (1) HRP980224A2 (es)
PE (1) PE68499A1 (es)
ZA (1) ZA983350B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673782B2 (en) * 1999-04-29 2004-01-06 Wisconsin Alumni Research Foundation Treatment of systemic lupus erythematosis
WO2004098522A2 (en) * 2003-04-30 2004-11-18 Bioxell S.P.A. Gemini vitamin d3 compounds and methods of use thereof
US20050113348A1 (en) * 2003-06-12 2005-05-26 Yanchun Li Vitamin D and vitamin D analogs or derivatives as new anti-hypertensive agents
US20060171983A1 (en) * 2003-07-30 2006-08-03 Jin Tian Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease
US20050107350A1 (en) * 2003-08-22 2005-05-19 Pharmacia Corporation Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith
WO2005074389A2 (ja) * 2004-02-03 2005-08-18 Chugai Pharmaceutical Co Ltd ビタミンｄ化合物及びそれらの合成中間体の合成方法
US20080039434A1 (en) * 2004-03-01 2008-02-14 Bioxell S. P.A. Treatment of Interstitial Cystitis with Vitamin D Compounds
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
JP2008538114A (ja) * 2005-03-23 2008-10-09 ビオクセル エッセ ピ ア ２０−アルキル、ジェミニビタミンｄ３化合物及びその使用方法
CN101198336A (zh) * 2005-03-23 2008-06-11 拜奥艾克塞尔股份公司 20－烷基双生维生素d3化合物及其使用方法
WO2007038250A2 (en) * 2005-09-23 2007-04-05 Bioxell S.P.A. 1,25 - dihydroxy, 20-cyclopropyl, 26-27- deuteroalkyl vitamin d3 compounds and methods of use thereof
US20080280859A1 (en) * 2005-10-19 2008-11-13 Bioxell S.P.A. Gemini vitamin d3 compounds and methods of use thereof
US20100009949A1 (en) * 2006-03-24 2010-01-14 Bioxell S.P.A. Novel method
US20120184514A1 (en) * 2009-07-01 2012-07-19 Vitamin Derivatives Inc. Vitamin d compounds and methods for preparing same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs

Also Published As

Publication number Publication date
PE68499A1 (es) 1999-07-10
HRP980224A2 (en) 1999-04-30
CO4940443A1 (es) 2000-07-24
US6030962A (en) 2000-02-29
AR012598A1 (es) 2000-11-08

Similar Documents

Publication Publication Date Title
EP0767974A4 (en) ELECTROCHEMICAL LUMINESCENT DEVICES
HK1068210A1 (en) Illudin analogs usefull as antitumor agents
SG70009A1 (en) Vitamin d3 analogs
GB2345698B (en) Phthalocyanine analogs
HK1030618A1 (en) Microencapsulated rubber additive
GB2305676B (en) Cord equipped with connector
ZA983350B (en) Vitamin D3 analogs with bis c-20 side chains
EP0996458A4 (en) SANDRAMYCIN ANALOG
HRP970274A2 (en) Fluorinated vitamin d3 analogs
SG70010A1 (en) Fluorinated vitamin d3 analogs
EP0737688A3 (de) Silane mit verzweigten Alkylketten
GB2323893B (en) Chain guide assembly
GB9700664D0 (en) Anti-cancer agents
AU135142S (en) Side saddle merchandiser
AU132858S (en) Wetsuit
GB2324284B (en) Traction means
GB9726237D0 (en) Safety chain
GB9416973D0 (en) Carbon side chain
PL107093U1 (en) Versatile half-mask
TW361709U (en) Improved structure for safety sockets
LT97056A (en) Assembly with rope traction
GB9817207D0 (en) Links
TW360187U (en) Moist-throat structure for improvement type diving equipment
TW353955U (en) Running simulator
PL318841A1 (en) Electrolyser