ZA978413B - Hydroquinone derivative and pharmaceutical use thereof. - Google Patents
Hydroquinone derivative and pharmaceutical use thereof.Info
- Publication number
- ZA978413B ZA978413B ZA9708413A ZA978413A ZA978413B ZA 978413 B ZA978413 B ZA 978413B ZA 9708413 A ZA9708413 A ZA 9708413A ZA 978413 A ZA978413 A ZA 978413A ZA 978413 B ZA978413 B ZA 978413B
- Authority
- ZA
- South Africa
- Prior art keywords
- group
- hydrogen atom
- alkyl group
- oxo
- hydroquinone derivative
- Prior art date
Links
- 125000000687 hydroquinonyl group Chemical class C1(O)=C(C=C(O)C=C1)* 0.000 title abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 125000004043 oxo group Chemical group O=* 0.000 abstract 4
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24827296 | 1996-09-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA978413B true ZA978413B (en) | 1998-03-26 |
Family
ID=17175664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9708413A ZA978413B (en) | 1996-09-19 | 1997-09-18 | Hydroquinone derivative and pharmaceutical use thereof. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5821247A (xx) |
| EP (1) | EP0831092B1 (xx) |
| AT (1) | ATE194838T1 (xx) |
| AU (1) | AU716992B2 (xx) |
| CA (1) | CA2216288C (xx) |
| DE (1) | DE69702580T2 (xx) |
| DK (1) | DK0831092T3 (xx) |
| ES (1) | ES2149548T3 (xx) |
| GR (1) | GR3034418T3 (xx) |
| NO (1) | NO313413B1 (xx) |
| NZ (1) | NZ328769A (xx) |
| PT (1) | PT831092E (xx) |
| ZA (1) | ZA978413B (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2002119574A (ru) * | 1999-12-23 | 2004-01-10 | Нитромед, Инк. (Us) | Нитрозированные и нитрозилированные ингибиторы циклооксигеназы-2, композиции на их основе и способы их применения |
| JPWO2004026842A1 (ja) * | 2002-09-20 | 2006-01-12 | 住友製薬株式会社 | 新規ウラシル誘導体及びその医薬用途 |
| EP3456707B1 (en) | 2007-11-06 | 2020-04-15 | PTC Therapeutics, Inc. | 4- (p-quinonyl)-2-hydroxybutanamide derivatives for treatment of mitochondrial diseases |
| WO2016100579A1 (en) | 2014-12-16 | 2016-06-23 | Edison Pharmaceuticals, Inc., | Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide |
| EP3359521A1 (en) * | 2015-10-08 | 2018-08-15 | Khondrion Ip B.V. | Novel compounds for treating mitochondrial disease |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5661153A (en) * | 1994-07-19 | 1997-08-26 | Japan Energy Corporation | 1-arylpyrimidine derivatives and pharmaceutical use thereof |
-
1997
- 1997-09-16 US US08/933,208 patent/US5821247A/en not_active Expired - Fee Related
- 1997-09-16 AU AU37601/97A patent/AU716992B2/en not_active Ceased
- 1997-09-17 AT AT97250280T patent/ATE194838T1/de not_active IP Right Cessation
- 1997-09-17 ES ES97250280T patent/ES2149548T3/es not_active Expired - Lifetime
- 1997-09-17 EP EP97250280A patent/EP0831092B1/en not_active Expired - Lifetime
- 1997-09-17 DK DK97250280T patent/DK0831092T3/da active
- 1997-09-17 PT PT97250280T patent/PT831092E/pt unknown
- 1997-09-17 DE DE69702580T patent/DE69702580T2/de not_active Expired - Fee Related
- 1997-09-18 ZA ZA9708413A patent/ZA978413B/xx unknown
- 1997-09-18 NZ NZ328769A patent/NZ328769A/en unknown
- 1997-09-18 NO NO19974313A patent/NO313413B1/no unknown
- 1997-09-19 CA CA002216288A patent/CA2216288C/en not_active Expired - Fee Related
-
1998
- 1998-07-10 US US09/113,826 patent/US5877318A/en not_active Expired - Fee Related
-
2000
- 2000-09-18 GR GR20000402106T patent/GR3034418T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5821247A (en) | 1998-10-13 |
| CA2216288A1 (en) | 1998-03-19 |
| DE69702580D1 (de) | 2000-08-24 |
| EP0831092A2 (en) | 1998-03-25 |
| US5877318A (en) | 1999-03-02 |
| AU716992B2 (en) | 2000-03-16 |
| NZ328769A (en) | 1998-07-28 |
| NO974313L (no) | 1998-03-20 |
| DK0831092T3 (da) | 2000-10-16 |
| AU3760197A (en) | 1998-03-26 |
| DE69702580T2 (de) | 2001-03-08 |
| GR3034418T3 (en) | 2000-12-29 |
| PT831092E (pt) | 2000-10-31 |
| NO313413B1 (no) | 2002-09-30 |
| EP0831092B1 (en) | 2000-07-19 |
| ES2149548T3 (es) | 2000-11-01 |
| EP0831092A3 (en) | 1998-04-08 |
| NO974313D0 (no) | 1997-09-18 |
| ATE194838T1 (de) | 2000-08-15 |
| CA2216288C (en) | 2006-02-07 |
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