ZA974325B - Crosslinked protein crystal formulations and their use as a catalysts in organic solvents. - Google Patents

Crosslinked protein crystal formulations and their use as a catalysts in organic solvents.

Info

Publication number
ZA974325B
ZA974325B ZA9704325A ZA974325A ZA974325B ZA 974325 B ZA974325 B ZA 974325B ZA 9704325 A ZA9704325 A ZA 9704325A ZA 974325 A ZA974325 A ZA 974325A ZA 974325 B ZA974325 B ZA 974325B
Authority
ZA
South Africa
Prior art keywords
catalysts
organic solvents
protein crystal
crosslinked protein
crystal formulations
Prior art date
Application number
ZA9704325A
Other languages
English (en)
Inventor
Nazer K Khalaf
Original Assignee
Altus Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altus Biologics Inc filed Critical Altus Biologics Inc
Publication of ZA974325B publication Critical patent/ZA974325B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
ZA9704325A 1996-05-24 1997-05-19 Crosslinked protein crystal formulations and their use as a catalysts in organic solvents. ZA974325B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/652,964 US5932212A (en) 1996-05-24 1996-05-24 Crosslinked protein crystal formulations and their use as catalysts in organic solvents

Publications (1)

Publication Number Publication Date
ZA974325B true ZA974325B (en) 1997-12-18

Family

ID=24618946

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9704325A ZA974325B (en) 1996-05-24 1997-05-19 Crosslinked protein crystal formulations and their use as a catalysts in organic solvents.

Country Status (13)

Country Link
US (2) US5932212A (en:Method)
EP (1) EP0906417B1 (en:Method)
JP (2) JP4279351B2 (en:Method)
KR (1) KR20000015993A (en:Method)
AR (1) AR007211A1 (en:Method)
AT (1) ATE393216T1 (en:Method)
AU (1) AU3072897A (en:Method)
DE (1) DE69738648T2 (en:Method)
DK (1) DK0906417T3 (en:Method)
ID (1) ID17817A (en:Method)
IN (1) IN191060B (en:Method)
WO (1) WO1997044445A1 (en:Method)
ZA (1) ZA974325B (en:Method)

Families Citing this family (38)

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WO1992009750A1 (en) * 1990-11-29 1992-06-11 Willis Richard R Floating contaminant containment systems
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
ATE464123T1 (de) * 1997-06-20 2010-04-15 Univ New York Elektrosprühen von lösungen zur massenherstellung von chips und molekülbibliotheken
US6833275B1 (en) * 1997-07-22 2004-12-21 Roche Diagnostics Gmbh Gold conjugates containing detergent
US6500933B1 (en) 1997-09-05 2002-12-31 Altus Biologics Inc. Methods of preparing carbohydrate crosslinked glycoprotein crystals
DE69839563D1 (de) * 1997-09-05 2008-07-10 Altus Pharmaceuticals Inc Kohlenhydrat-vernetzte glykoproteinkristalle
ZA988461B (en) * 1997-09-18 1999-03-30 Idec Pharma Corp Synergistic composition and methods for treating neoplastic or cancerous growths and for restoring or boosting hematopoiesis
US6541606B2 (en) * 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
JP4965022B2 (ja) * 1998-04-27 2012-07-04 アルタス ファーマシューティカルズ インコーポレイテッド 安定化されたタンパク質結晶、それを含む処方物、およびそれを作製する方法
US6979561B1 (en) 1998-10-09 2005-12-27 Gilead Sciences, Inc. Non-homogeneous systems for the resolution of enantiomeric mixtures
BRPI9914375B1 (pt) * 1998-10-09 2018-03-13 Altus Pharmaceuticals Inc. Sistemas heterogêneos para resolução de misturas enantioméricas
DE19903125B4 (de) * 1999-01-27 2006-01-05 Sanofi-Aventis Deutschland Gmbh Verfahren zur Trocknung von Kristallen von Insulin oder Insulinanaloga
AU6574400A (en) * 1999-08-18 2001-03-13 Hydrios Biotechnology Oy Process for the preparation and simultaneous separation of enzyme-catalysed products
US7608445B1 (en) 1999-12-29 2009-10-27 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US7300775B2 (en) 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
US20040014195A1 (en) * 1999-12-29 2004-01-22 Diversa Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US7521216B2 (en) * 1999-12-29 2009-04-21 Verenium Corporation Nitrilases and methods for making and using them
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
EP1292823A1 (en) * 2000-05-23 2003-03-19 Radiometer Medical A/S A sensor membrane, a method for the preparation thereof, a sensor and a layered membrane structure for such sensor
KR20030074693A (ko) * 2000-12-28 2003-09-19 알투스 바이올로직스 인코포레이티드 전항체 및 이의 단편의 결정과 이의 제조 및 사용 방법
CA2451185A1 (en) 2001-06-21 2003-01-03 Altus Biologics, Inc. Spherical protein particles and methods of making and using them
AU2003251523A1 (en) 2002-06-13 2003-12-31 Diversa Corporation Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid
US9035123B2 (en) 2002-10-01 2015-05-19 The Procter & Gamble Company Absorbent article having a lotioned topsheet
CA2512001A1 (en) * 2002-12-31 2004-07-22 Altus Pharmaceuticals Inc. Complexes of protein crystals and ionic polymers
BR0317888A (pt) * 2002-12-31 2005-12-06 Altus Pharmaceuticals Inc Cristais do hormÈnio do crescimento humano e processos para preparação dos mesmos
DK1699921T3 (da) * 2004-01-01 2010-02-01 Council Scient Ind Res Fremgangsmåde til fremstilling af tværbundne proteinkrystaller
MX2007004534A (es) * 2004-10-14 2007-11-08 Altus Pharmaceuticals Inc Composiciones que contienen lipasa, proteasa y amilasa para tratar la insuficiencia pancreatica.
WO2007050100A2 (en) * 2004-11-24 2007-05-03 Industrial Science & Technology Network, Inc. Immobilized enzymes and processes for preparing and using same
US20060223765A1 (en) * 2005-03-30 2006-10-05 Kimberly-Clark Worldwide, Inc. Method for inhibiting and/or treating vaginal infection
GB0513888D0 (en) * 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
WO2007076131A2 (en) * 2005-12-23 2007-07-05 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them
US20100047413A1 (en) * 2006-09-15 2010-02-25 Cabalka Tourtellotte Leanne M Method of using amphiphilic multiblock copolymers in food
CA2679503A1 (en) 2007-03-01 2008-09-04 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
IL183084A0 (en) * 2007-05-09 2007-09-20 Trans Biodisel Ltd Modified-immobilized enzymes of high tolerance to hydrophilic substrates in organic media
CN101717766B (zh) * 2009-12-01 2012-07-18 暨南大学 蛋白质酶的微水介质固定化方法
WO2012003336A2 (en) 2010-06-30 2012-01-05 Codexis, Inc. Chemically modified carbonic anhydrases useful in carbon capture systems
US9303255B2 (en) 2010-08-26 2016-04-05 Aisin Seiki Kabushiki Kaisha Electrode having enzyme crystals immobilized thereon, method for producing electrode having enzyme crystals immobilized thereon, and biological fuel cell and biosensor provided with electrode having enzyme crystals immobilized thereon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267234A (en) * 1978-03-17 1981-05-12 California Institute Of Technology Polyglutaraldehyde synthesis and protein bonding substrates
US4369226A (en) * 1979-03-19 1983-01-18 California Institute Of Technology Polyglutaraldehyde synthesis and protein bonding substrates
US5152903A (en) * 1988-12-19 1992-10-06 American Cyanamid Company Cross-linked cationic polymeric microparticles
HUT65904A (en) * 1990-08-03 1994-07-28 Vertex Pharma Method for immobilization of enzyme in the form of crosslinked crystals
GB9309243D0 (en) * 1993-05-05 1993-06-16 Allied Colloids Ltd Enzyme dispersions,their production and compositions containing them
ATE160582T1 (de) * 1993-05-20 1997-12-15 Loders Croklaan Bv Verfahren zur herstellung immobilisierter lipasen
ATE193319T1 (de) * 1993-12-03 2000-06-15 Buckman Labor Inc Enzymstabilisierung durch blockcopolymere
DE4344211A1 (de) * 1993-12-23 1995-06-29 Basf Ag Verfahren zur Erhöhung der Aktivität von hydrolytischen Enzymen

Also Published As

Publication number Publication date
AR007211A1 (es) 1999-10-13
JP2000514282A (ja) 2000-10-31
DK0906417T3 (da) 2008-07-21
ATE393216T1 (de) 2008-05-15
DE69738648T2 (de) 2009-05-28
DE69738648D1 (de) 2008-06-05
KR20000015993A (ko) 2000-03-25
US6042824A (en) 2000-03-28
JP4279351B2 (ja) 2009-06-17
IN191060B (en:Method) 2003-09-13
EP0906417A1 (en) 1999-04-07
AU3072897A (en) 1997-12-09
JP2008061652A (ja) 2008-03-21
EP0906417B1 (en) 2008-04-23
US5932212A (en) 1999-08-03
ID17817A (id) 1998-01-29
WO1997044445A1 (en) 1997-11-27

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