ATE393216T1 - Formulierungen vernetzter proteinkristalle und ihre verwendung als katalysatoren in organischen lösungsmitteln - Google Patents

Formulierungen vernetzter proteinkristalle und ihre verwendung als katalysatoren in organischen lösungsmitteln

Info

Publication number
ATE393216T1
ATE393216T1 AT97925652T AT97925652T ATE393216T1 AT E393216 T1 ATE393216 T1 AT E393216T1 AT 97925652 T AT97925652 T AT 97925652T AT 97925652 T AT97925652 T AT 97925652T AT E393216 T1 ATE393216 T1 AT E393216T1
Authority
AT
Austria
Prior art keywords
catalysts
formulations
cross
organic solvents
linked protein
Prior art date
Application number
AT97925652T
Other languages
German (de)
English (en)
Inventor
Nazer Khalaf
Original Assignee
Altus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altus Pharmaceuticals Inc filed Critical Altus Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE393216T1 publication Critical patent/ATE393216T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97925652T 1996-05-24 1997-05-20 Formulierungen vernetzter proteinkristalle und ihre verwendung als katalysatoren in organischen lösungsmitteln ATE393216T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/652,964 US5932212A (en) 1996-05-24 1996-05-24 Crosslinked protein crystal formulations and their use as catalysts in organic solvents

Publications (1)

Publication Number Publication Date
ATE393216T1 true ATE393216T1 (de) 2008-05-15

Family

ID=24618946

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97925652T ATE393216T1 (de) 1996-05-24 1997-05-20 Formulierungen vernetzter proteinkristalle und ihre verwendung als katalysatoren in organischen lösungsmitteln

Country Status (13)

Country Link
US (2) US5932212A (en:Method)
EP (1) EP0906417B1 (en:Method)
JP (2) JP4279351B2 (en:Method)
KR (1) KR20000015993A (en:Method)
AR (1) AR007211A1 (en:Method)
AT (1) ATE393216T1 (en:Method)
AU (1) AU3072897A (en:Method)
DE (1) DE69738648T2 (en:Method)
DK (1) DK0906417T3 (en:Method)
ID (1) ID17817A (en:Method)
IN (1) IN191060B (en:Method)
WO (1) WO1997044445A1 (en:Method)
ZA (1) ZA974325B (en:Method)

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WO1992009750A1 (en) * 1990-11-29 1992-06-11 Willis Richard R Floating contaminant containment systems
US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
AU747022B2 (en) * 1997-06-20 2002-05-09 New York University Electrospraying solutions of substances for mass fabrication of chips and libraries
US6833275B1 (en) * 1997-07-22 2004-12-21 Roche Diagnostics Gmbh Gold conjugates containing detergent
EP1009759B1 (en) 1997-09-05 2008-05-28 Altus Pharmaceuticals Inc. Carbohydrate crosslinked glycoprotein crystals
US6500933B1 (en) 1997-09-05 2002-12-31 Altus Biologics Inc. Methods of preparing carbohydrate crosslinked glycoprotein crystals
MY131805A (en) * 1997-09-18 2007-09-28 Biogen Idec Inc Synergistic composition and methods for treating neoplastic or cancerous growths and for restoring or boosting hematopoiesis.
US6541606B2 (en) * 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
CA2330476A1 (en) * 1998-04-27 1999-11-04 Altus Biologics Inc. Stabilized protein crystals, formulations containing them and methods of making them
KR101072439B1 (ko) * 1998-10-09 2011-10-11 알투스 파마슈티컬스 인코포레이티드 에난티오머 혼합물을 분할하기 위한 비균질 시스템
US6979561B1 (en) 1998-10-09 2005-12-27 Gilead Sciences, Inc. Non-homogeneous systems for the resolution of enantiomeric mixtures
DE19903125B4 (de) * 1999-01-27 2006-01-05 Sanofi-Aventis Deutschland Gmbh Verfahren zur Trocknung von Kristallen von Insulin oder Insulinanaloga
AU6574400A (en) * 1999-08-18 2001-03-13 Hydrios Biotechnology Oy Process for the preparation and simultaneous separation of enzyme-catalysed products
US20040014195A1 (en) * 1999-12-29 2004-01-22 Diversa Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US7521216B2 (en) * 1999-12-29 2009-04-21 Verenium Corporation Nitrilases and methods for making and using them
US7300775B2 (en) * 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
US7608445B1 (en) 1999-12-29 2009-10-27 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
WO2001090733A1 (en) * 2000-05-23 2001-11-29 Radiometer Medical A/S A sensor membrane, a method for the preparation thereof, a sensor and a layered membrane structure for such sensor
CA2433353C (en) * 2000-12-28 2017-03-21 Altus Biologics, Inc. Crystals of whole antibodies and fragments thereof and methods for making and using them
AU2002322295C1 (en) 2001-06-21 2008-12-18 Altus Pharmaceuticals Inc. Spherical protein particles and methods of making and using them
AU2003251523A1 (en) 2002-06-13 2003-12-31 Diversa Corporation Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid
US9035123B2 (en) 2002-10-01 2015-05-19 The Procter & Gamble Company Absorbent article having a lotioned topsheet
MXPA05007181A (es) * 2002-12-31 2006-04-07 Altus Pharmaceuticals Inc Cristales de la hormona de crecimiento humano y metodos para prepararlos.
JP2006523609A (ja) * 2002-12-31 2006-10-19 アルタス ファーマシューティカルズ インコーポレイテッド タンパク質結晶およびイオン性ポリマーの複合体
WO2005066341A1 (en) * 2004-01-01 2005-07-21 Council Of Scientific & Industrial Research A method for the preparation of cross linked protein crystals
MX2007004534A (es) * 2004-10-14 2007-11-08 Altus Pharmaceuticals Inc Composiciones que contienen lipasa, proteasa y amilasa para tratar la insuficiencia pancreatica.
WO2007050100A2 (en) * 2004-11-24 2007-05-03 Industrial Science & Technology Network, Inc. Immobilized enzymes and processes for preparing and using same
US20060223765A1 (en) * 2005-03-30 2006-10-05 Kimberly-Clark Worldwide, Inc. Method for inhibiting and/or treating vaginal infection
GB0513888D0 (en) * 2005-07-06 2005-08-10 Btg Int Ltd Core 2 GLCNAC-T Inhibitors II
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
US20090023629A1 (en) * 2005-12-23 2009-01-22 Altus Pharmaceuticals Inc. Compositions comprising polycation-complexed protein crystals and methods of treatment using them
WO2008034082A2 (en) * 2006-09-15 2008-03-20 Maroon Biotech, Corporation Method of using amphiphilic multiblock copolymers in food
CA2679503A1 (en) 2007-03-01 2008-09-04 Verenium Corporation Nitrilases, nucleic acids encoding them and methods for making and using them
IL183084A0 (en) * 2007-05-09 2007-09-20 Trans Biodisel Ltd Modified-immobilized enzymes of high tolerance to hydrophilic substrates in organic media
CN101717766B (zh) * 2009-12-01 2012-07-18 暨南大学 蛋白质酶的微水介质固定化方法
US8354262B2 (en) 2010-06-30 2013-01-15 Codexis, Inc. Chemically modified carbonic anhydrases useful in carbon capture systems
US9303255B2 (en) 2010-08-26 2016-04-05 Aisin Seiki Kabushiki Kaisha Electrode having enzyme crystals immobilized thereon, method for producing electrode having enzyme crystals immobilized thereon, and biological fuel cell and biosensor provided with electrode having enzyme crystals immobilized thereon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267234A (en) * 1978-03-17 1981-05-12 California Institute Of Technology Polyglutaraldehyde synthesis and protein bonding substrates
US4369226A (en) * 1979-03-19 1983-01-18 California Institute Of Technology Polyglutaraldehyde synthesis and protein bonding substrates
US5152903A (en) * 1988-12-19 1992-10-06 American Cyanamid Company Cross-linked cationic polymeric microparticles
DK0550450T3 (da) * 1990-08-03 2003-09-08 Vertex Pharma Anvendelse af tværbundne krystaller som ny fremgangsmåde til immobilisering af enzymer
GB9309243D0 (en) * 1993-05-05 1993-06-16 Allied Colloids Ltd Enzyme dispersions,their production and compositions containing them
WO1994028118A1 (en) * 1993-05-20 1994-12-08 Loders Croklaan B.V. Immobilized lipases
EP0731834B1 (en) * 1993-12-03 2000-05-24 Buckman Laboratories International, Inc. Enzyme stabilization by block-copolymers
DE4344211A1 (de) * 1993-12-23 1995-06-29 Basf Ag Verfahren zur Erhöhung der Aktivität von hydrolytischen Enzymen

Also Published As

Publication number Publication date
ID17817A (id) 1998-01-29
AU3072897A (en) 1997-12-09
US6042824A (en) 2000-03-28
IN191060B (en:Method) 2003-09-13
WO1997044445A1 (en) 1997-11-27
EP0906417B1 (en) 2008-04-23
JP2000514282A (ja) 2000-10-31
JP4279351B2 (ja) 2009-06-17
US5932212A (en) 1999-08-03
AR007211A1 (es) 1999-10-13
JP2008061652A (ja) 2008-03-21
EP0906417A1 (en) 1999-04-07
DE69738648T2 (de) 2009-05-28
KR20000015993A (ko) 2000-03-25
DE69738648D1 (de) 2008-06-05
DK0906417T3 (da) 2008-07-21
ZA974325B (en) 1997-12-18

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