ZA971670B - Aminotetralin derivatives and compositions and method of use thereof. - Google Patents
Aminotetralin derivatives and compositions and method of use thereof.Info
- Publication number
- ZA971670B ZA971670B ZA9701670A ZA971670A ZA971670B ZA 971670 B ZA971670 B ZA 971670B ZA 9701670 A ZA9701670 A ZA 9701670A ZA 971670 A ZA971670 A ZA 971670A ZA 971670 B ZA971670 B ZA 971670B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydrogen
- compositions
- aminotetralin derivatives
- alkoxy
- halogen
- Prior art date
Links
- JRZGPXSSNPTNMA-UHFFFAOYSA-N 1,2,3,4-tetrahydronaphthalen-1-amine Chemical class C1=CC=C2C(N)CCCC2=C1 JRZGPXSSNPTNMA-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 150000002431 hydrogen Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 208000016285 Movement disease Diseases 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1264096P | 1996-03-01 | 1996-03-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA971670B true ZA971670B (en) | 1997-09-01 |
Family
ID=21755962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9701670A ZA971670B (en) | 1996-03-01 | 1997-02-26 | Aminotetralin derivatives and compositions and method of use thereof. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5807897A (de) |
| EP (1) | EP0883599B1 (de) |
| JP (1) | JP4083221B2 (de) |
| KR (1) | KR19990087369A (de) |
| CN (1) | CN1212682A (de) |
| AT (1) | ATE218535T1 (de) |
| AU (1) | AU733264B2 (de) |
| DE (1) | DE69713067T2 (de) |
| IL (1) | IL125907A0 (de) |
| NO (1) | NO983990L (de) |
| NZ (1) | NZ330974A (de) |
| TW (1) | TW409113B (de) |
| WO (1) | WO1997031887A1 (de) |
| ZA (1) | ZA971670B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9726736D0 (en) | 1997-12-18 | 1998-02-18 | Zeneca Ltd | Chemical compounds |
| GB9914015D0 (en) * | 1999-06-17 | 1999-08-18 | Zeneca Ltd | Chemical compounds |
| EP1140863A1 (de) * | 1998-12-24 | 2001-10-10 | AstraZeneca AB | 1,4-diazacycloheptanderivate nützlich zur behandlung von neurologische störungen |
| GB9914025D0 (en) * | 1999-06-17 | 1999-08-18 | Zeneca Ltd | Chemical compounds |
| GB9914024D0 (en) * | 1999-06-17 | 1999-08-18 | Zeneca Ltd | Chemical compounds |
| PL1658277T3 (pl) * | 2003-08-18 | 2012-10-31 | H Lundbeck As | Sól bursztynianowa i malonianowa trans-4-((1R,3S)-6-chloro-3-fenyloindan-1-ylo)-1,2,2-tri-metylopiperazyny i zastosowanie jako lek |
| TWI376373B (en) * | 2005-02-16 | 2012-11-11 | Lundbeck & Co As H | Crystalline base of a pharmaceutical compound |
| TWI453198B (zh) * | 2005-02-16 | 2014-09-21 | Lundbeck & Co As H | 製造反式-1-((1r,3s)-6-氯基-3-苯基茚滿-1-基) -3 , 3 -二甲基六氫吡與其鹽類之方法及製造4-((1r , 3s）-6 -氯基-3-苯基茚滿-1-基 )-1,2,2-三甲基六氫吡與其鹽類之方法 |
| CN102065861B (zh) * | 2008-05-07 | 2013-10-16 | H.隆德贝克有限公司 | 反式-4-((1r，3s)-6-氯-3-苯基茚满-1-基)-1，2，2-三甲基哌嗪用于改善认知的用途 |
| CN102170884A (zh) * | 2008-10-03 | 2011-08-31 | H.隆德贝克有限公司 | 口服制剂 |
| MX2023014630A (es) | 2021-06-08 | 2024-01-30 | Atai Therapeutics Inc | Activadores de dimetoxifenilalquilamina de receptores de serotonina. |
| EP4457203A4 (de) * | 2021-12-27 | 2025-12-17 | Atai Therapeutics Inc | Aminotetralin-aktivatoren von serotoninrezeptoren |
| US12343319B2 (en) | 2023-05-01 | 2025-07-01 | Atai Therapeutics, Inc. | Compositions and methods for treatment of diseases and disorders |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4320148A (en) * | 1980-11-24 | 1982-03-16 | Smithkline Corporation | 2-Aminotetralin compounds, pharmaceutical compositions and method of producing central alpha1 agonist activity |
| US5225596A (en) * | 1989-01-09 | 1993-07-06 | The Upjohn Company | Halo substituted aminotetralins |
| SE8904127D0 (sv) * | 1989-12-07 | 1989-12-07 | Astra Ab | New biocyclic amino-substituted compounds |
| EP0450238A1 (de) * | 1990-03-30 | 1991-10-09 | Merrell Dow Pharmaceuticals Inc. | Verbindungen für die Behandlung von Migräne |
-
1997
- 1997-02-21 US US08/804,195 patent/US5807897A/en not_active Expired - Lifetime
- 1997-02-25 CN CN97192657A patent/CN1212682A/zh active Pending
- 1997-02-25 IL IL12590797A patent/IL125907A0/xx unknown
- 1997-02-25 JP JP53069697A patent/JP4083221B2/ja not_active Expired - Fee Related
- 1997-02-25 KR KR1019980706779A patent/KR19990087369A/ko not_active Withdrawn
- 1997-02-25 NZ NZ330974A patent/NZ330974A/xx unknown
- 1997-02-25 DE DE69713067T patent/DE69713067T2/de not_active Expired - Lifetime
- 1997-02-25 AT AT97905261T patent/ATE218535T1/de not_active IP Right Cessation
- 1997-02-25 AU AU18879/97A patent/AU733264B2/en not_active Ceased
- 1997-02-25 WO PCT/GB1997/000516 patent/WO1997031887A1/en not_active Ceased
- 1997-02-25 EP EP97905261A patent/EP0883599B1/de not_active Expired - Lifetime
- 1997-02-26 ZA ZA9701670A patent/ZA971670B/xx unknown
- 1997-02-26 TW TW086102356A patent/TW409113B/zh not_active IP Right Cessation
-
1998
- 1998-08-31 NO NO983990A patent/NO983990L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TW409113B (en) | 2000-10-21 |
| WO1997031887A1 (en) | 1997-09-04 |
| EP0883599A1 (de) | 1998-12-16 |
| JP4083221B2 (ja) | 2008-04-30 |
| NZ330974A (en) | 2000-05-26 |
| AU733264B2 (en) | 2001-05-10 |
| KR19990087369A (ko) | 1999-12-27 |
| CN1212682A (zh) | 1999-03-31 |
| DE69713067D1 (de) | 2002-07-11 |
| NO983990D0 (no) | 1998-08-31 |
| NO983990L (no) | 1998-08-31 |
| ATE218535T1 (de) | 2002-06-15 |
| DE69713067T2 (de) | 2002-12-19 |
| IL125907A0 (en) | 1999-04-11 |
| AU1887997A (en) | 1997-09-16 |
| JP2000506137A (ja) | 2000-05-23 |
| EP0883599B1 (de) | 2002-06-05 |
| US5807897A (en) | 1998-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2432085A1 (en) | Indole derivatives and their use as 5-ht2b and 5-ht2c receptor ligands | |
| CA2387517A1 (en) | Novel biaryl ether derivatives useful as monoamine reuptake inhibitors | |
| PL316080A1 (en) | Pharmaceutic composition for sublingual or intrabuccal administration | |
| IL142768A0 (en) | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity | |
| IL125907A0 (en) | Aminotetralin derivatives and compositions and method of use thereof | |
| AP9701019A0 (en) | Phenylamino-substituted tricycle derivatives. | |
| MX9701292A (es) | Compuestos espiro-azabiciclicos utiles en la terapia. | |
| BG106251A (en) | Levodopa (carbidopa) entacapone pharmaceutical preparation | |
| CA2268886A1 (en) | Aminothiophenecarboxamides | |
| TW225513B (de) | ||
| IL127368A0 (en) | 1,2,4-Benzothiadiazine derivatives their preparation and use | |
| CA2113916A1 (en) | 6-Chloro-5-Fluoro-3-(2-Thenoyl)-2-Oxindole-1-Carboxamide as an Analgesic and Anti-Inflammatory Agent | |
| CA2283255A1 (en) | Use of r-nsaid's for the prevention of alzheimer's disease | |
| ZA941963B (en) | Substituted (arylalkoxybenzyl)aminopropanamide derivatives and process for their preparation | |
| LV11728A (lv) | Farmaceitiska kompozicija | |
| GB9108629D0 (en) | Heterocyclic pharmaceutical compounds,preparation and use | |
| GB9306899D0 (en) | Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation | |
| TW349864B (en) | Use of N-(pyridinyl)-1H-indol-a-amines for the preparation of a medicament for the treatment of obsessive-compulsive disorders | |
| AP9801235A0 (en) | Erythromycin derivatives. | |
| AP9901559A0 (en) | Tricyclic 3-keto derivatives of 6-0-methylerythromycin. | |
| MXPA98005355A (es) | Derivados de 5-[(heteroaril) alquil]-3 -oxo-pirido [1, 2-a]bencimidazol -4-carboxamida utiles en el tratamiento de trastornos del sistema nervioso central. | |
| WO1994016705A3 (en) | Pharmaceutical composition containing 5-morpholinomethyl-3-(4-chlorobenzylideneamine)-2-oxazolidinone and its use for the treatment of cns disorders | |
| MX9701528A (es) | Derivados de 1, 1, 2,- trifenilbut-1-eno para tratar la enfermedad de alzheimer. | |
| ES2150400A6 (es) | Una composicion para el tratamiento de desordenes ulcerosos del tracto gastrointestinal. | |
| UA66755C2 (en) | Derivatives of condensed 1,2,4-thiadiazine, a method for the preparation thereof, pharmaceutical composition and a method for treatment or prevention of endocrine system diseases |