ZA967874B - Use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of ginkgolides - Google Patents

Use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of ginkgolides

Info

Publication number
ZA967874B
ZA967874B ZA967874A ZA967874A ZA967874B ZA 967874 B ZA967874 B ZA 967874B ZA 967874 A ZA967874 A ZA 967874A ZA 967874 A ZA967874 A ZA 967874A ZA 967874 B ZA967874 B ZA 967874B
Authority
ZA
South Africa
Prior art keywords
ginkgolides
solubilization
family
derivatives
aggregating agents
Prior art date
Application number
ZA967874A
Other languages
English (en)
Inventor
Jacques Defaye
Valerie Laine
Florence Djedaini-Pillard
Bruno Perly
Original Assignee
Commissariat Energie Atomique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique filed Critical Commissariat Energie Atomique
Publication of ZA967874B publication Critical patent/ZA967874B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Polymers & Plastics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
ZA967874A 1995-09-20 1996-09-18 Use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of ginkgolides ZA967874B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9511040A FR2738828B1 (fr) 1995-09-20 1995-09-20 Utilisation de cyclodextrines naturelles et de leurs derives pour la solubilisation d'agents anti-agregants plaquettaires de la famille des ginkgolides

Publications (1)

Publication Number Publication Date
ZA967874B true ZA967874B (en) 1997-04-08

Family

ID=9482755

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA967874A ZA967874B (en) 1995-09-20 1996-09-18 Use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of ginkgolides

Country Status (7)

Country Link
US (1) US5798342A (ja)
EP (1) EP0764659A1 (ja)
JP (1) JPH09165345A (ja)
AU (1) AU705323B2 (ja)
FR (1) FR2738828B1 (ja)
HU (1) HUP9602557A3 (ja)
ZA (1) ZA967874B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19829516B4 (de) * 1998-07-02 2004-08-26 Dr. Willmar Schwabe Gmbh & Co. Kg Wasserlöslicher nativer Trockenextrakt aus Gingko biloba mit hohem Gehalt an Terpenoiden und Flavonglykosiden
EP1503632A1 (en) * 2002-05-02 2005-02-09 Volker Kuellmer Coated, agglomerated phytochemicals
CN107773763A (zh) * 2016-08-25 2018-03-09 江苏康缘药业股份有限公司 银杏内酯K‑β‑环糊精包合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5211953A (en) * 1989-07-21 1993-05-18 Suntory, Limited Liver function improver
DE69034181T2 (de) * 1989-07-21 2006-01-26 Suntory Ltd. Kapsel, enthaltend ein Dioxabicyclo(3.3.0)oktan
DE3940091A1 (de) * 1989-12-04 1991-06-06 Schwabe Willmar Gmbh & Co Extrakt aus blaettern von ginkgo biloba, verfahren zu seiner herstellung und den extrakt enthaltende arzneimittel
DE3940092A1 (de) * 1989-12-04 1991-06-06 Schwabe Willmar Gmbh & Co Extrakt aus blaettern von ginkgo biloba, verfahren zu seiner herstellung und den extrakt enthaltende arzneimittel
JPH0724560B2 (ja) * 1990-06-01 1995-03-22 株式会社ヤクルト本社 植物体エキス含有飲料
DE4030758A1 (de) * 1990-09-28 1992-04-02 Schwabe Willmar Gmbh & Co Extrakt aus blaettern von ginkgo biloba, insbesondere zur intravenoesen injektion oder infusion, verfahren zu seiner herstellung und den extrakt enthaltende ampullenpraeparate

Also Published As

Publication number Publication date
JPH09165345A (ja) 1997-06-24
EP0764659A1 (fr) 1997-03-26
HUP9602557A2 (en) 1997-05-28
US5798342A (en) 1998-08-25
HUP9602557A3 (en) 1997-11-28
AU705323B2 (en) 1999-05-20
FR2738828A1 (fr) 1997-03-21
HU9602557D0 (en) 1996-11-28
FR2738828B1 (fr) 1997-10-17
AU6565096A (en) 1997-03-27

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