GB9106177D0 - Substituted diphenylethylenes and analogues or derivatives thereof - Google Patents

Substituted diphenylethylenes and analogues or derivatives thereof

Info

Publication number
GB9106177D0
GB9106177D0 GB919106177A GB9106177A GB9106177D0 GB 9106177 D0 GB9106177 D0 GB 9106177D0 GB 919106177 A GB919106177 A GB 919106177A GB 9106177 A GB9106177 A GB 9106177A GB 9106177 D0 GB9106177 D0 GB 9106177D0
Authority
GB
United Kingdom
Prior art keywords
analogues
derivatives
diphenylethylenes
substituted
substituted diphenylethylenes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB919106177A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ASTON MOLECULES Ltd
Original Assignee
ASTON MOLECULES Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ASTON MOLECULES Ltd filed Critical ASTON MOLECULES Ltd
Priority to GB919106177A priority Critical patent/GB9106177D0/en
Publication of GB9106177D0 publication Critical patent/GB9106177D0/en
Priority to PCT/GB1992/000498 priority patent/WO1992016486A1/en
Priority to AU13719/92A priority patent/AU1371992A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/54—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB919106177A 1991-03-22 1991-03-22 Substituted diphenylethylenes and analogues or derivatives thereof Pending GB9106177D0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB919106177A GB9106177D0 (en) 1991-03-22 1991-03-22 Substituted diphenylethylenes and analogues or derivatives thereof
PCT/GB1992/000498 WO1992016486A1 (en) 1991-03-22 1992-03-19 Substituted diphenylethylenes and analogues or derivatives thereof
AU13719/92A AU1371992A (en) 1991-03-22 1992-03-19 Substituted diphenylethylenes and analogues or derivatives thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919106177A GB9106177D0 (en) 1991-03-22 1991-03-22 Substituted diphenylethylenes and analogues or derivatives thereof

Publications (1)

Publication Number Publication Date
GB9106177D0 true GB9106177D0 (en) 1991-05-08

Family

ID=10692073

Family Applications (1)

Application Number Title Priority Date Filing Date
GB919106177A Pending GB9106177D0 (en) 1991-03-22 1991-03-22 Substituted diphenylethylenes and analogues or derivatives thereof

Country Status (3)

Country Link
AU (1) AU1371992A (en)
GB (1) GB9106177D0 (en)
WO (1) WO1992016486A1 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1338645C (en) * 1987-01-06 1996-10-15 George R. Pettit Isolation, structural elucidation and synthesis of novel antineoplastic substances denominated "combretastatins"
IT1256354B (en) * 1992-08-31 1995-12-01 Francesca Pelizzoni ANTI-TUMORAL ACTIVITIES OF COMBRETASTATINA AND PROCEDURE FOR THEIR PREPARATION
US5561122A (en) * 1994-12-22 1996-10-01 Arizona Board Of Regents Acting On Behalf Of Arizona State University Combretastatin A-4 prodrug
TW334418B (en) 1995-03-07 1998-06-21 Ajinomoto Kk Stilbene derivatives and pharmaceutical compositions
CA2314238C (en) * 1998-01-09 2008-09-02 Arizona Board Of Regents, A Body Corporate, Acting On Behalf Of Arizona State University Synthesis of combretastatin a-4 prodrugs and trans-isomers thereof
BR9909393A (en) 1998-04-03 2000-12-26 Ajinomoto Kk Antitumor agent, use of a stilbene derivative and a platinum coordination compound, and, process for the treatment or improvement of a tumor
GB9903403D0 (en) * 1999-02-16 1999-04-07 Angiogene Pharm Ltd Substituted stilbene compounds with vascular damaging activity
JP2002537262A (en) * 1999-02-18 2002-11-05 オキシジェン，インコーポレイティド Compositions and methods for use in targeting vascular disruption
GB9918912D0 (en) * 1999-08-12 1999-10-13 Angiogene Pharm Ltd New stilbenes with vascular damaging activity
US7321050B2 (en) 1999-12-06 2008-01-22 Welichem Biotech Inc. Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues
CA2393297C (en) * 1999-12-06 2010-10-05 Welichem Biotech Inc. Polyhydroxystilbenes as antipsoriatic agents and protein kinase inhibitors
DK1278758T3 (en) * 2000-04-27 2012-01-23 Univ Arizona Combretastatin A-1 Phosphate and Combretastatin B-1 Phosphate Prodrugs
AU2001296215A1 (en) 2000-07-17 2002-01-30 Oxi-Gene, Inc. Efficient method of synthesizing combretastatin a-4 prodrugs
GB0019944D0 (en) * 2000-08-15 2000-09-27 Angiogene Pharm Ltd Compositions with vascular damaging activity
US20050153939A1 (en) 2003-09-10 2005-07-14 Bristol-Myers Squibb Company Combretastatin A-4 phosphate prodrug mono-and di-organic amine salts, mono-and di-amino acid salts, and mono-and di-amino acid ester salts
US6670344B2 (en) * 2000-09-14 2003-12-30 Bristol-Myers Squibb Company Combretastatin A-4 phosphate prodrug mono- and di-organic amine salts, mono- and di- amino acid salts, and mono- and di-amino acid ester salts
DK1320534T3 (en) * 2000-09-14 2005-08-22 Bristol Myers Squibb Co Combrestatin A-4-phosphate prodrug salts with nitrogenous compounds
CA2432640A1 (en) 2000-12-21 2002-06-27 Cancer Research Technology Limited Substituted stilbenes, their reactions and anticancer activity
JP2005507912A (en) 2001-10-26 2005-03-24 オキシジーン， インコーポレイテッド Functionalized stilbene derivatives as improved vascular targeting agents
AU2004218412A1 (en) 2003-02-28 2004-09-16 Oxigene, Inc. Compositions and methods with enhanced therapeutic activity
CN1312161C (en) * 2005-04-30 2007-04-25 中国科学院广州化学研究所 3-hydroxy-4,3',4',5'-tetromethoxy bibenzyl phosphate and its composition, prepn and application
CN1907989B (en) * 2005-08-02 2011-08-17 浙江天皇药业有限公司 Setoglaucine salt, preparation method thereof and medicinal composition containing the same
US8062880B2 (en) 2007-04-13 2011-11-22 Freeman Energy Corporation Biomass cultivation system and corresponding method of operation
JP5302328B2 (en) 2007-11-21 2013-10-02 オキシジーン， インコーポレイテッド Methods for treating hematopoietic neoplasms
WO2014089177A2 (en) 2012-12-04 2014-06-12 Massachusetts Institute Of Technology Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines
EP2972394A4 (en) 2013-03-15 2016-11-02 Sloan Kettering Inst Cancer Hsp90-targeted cardiac imaging and therapy
US11419934B2 (en) 2015-08-18 2022-08-23 Oncotelic Therapeutics, Inc. Use of VDAS to enhance immunomodulating therapies against tumors
WO2017197045A1 (en) 2016-05-11 2017-11-16 Movassaghi Mohammad Convergent and enantioselective total synthesis of communesin analogs
US11932650B2 (en) 2017-05-11 2024-03-19 Massachusetts Institute Of Technology Potent agelastatin derivatives as modulators for cancer invasion and metastasis
US10640508B2 (en) 2017-10-13 2020-05-05 Massachusetts Institute Of Technology Diazene directed modular synthesis of compounds with quaternary carbon centers
JP6912664B2 (en) 2017-11-10 2021-08-04 ダーマヴァント サイエンシーズ ゲーエムベーハー Process for preparing tapinarov
US20210009956A1 (en) 2018-03-30 2021-01-14 Kyoto University Cardiomyocyte maturation promoter
US11535634B2 (en) 2019-06-05 2022-12-27 Massachusetts Institute Of Technology Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1338645C (en) * 1987-01-06 1996-10-15 George R. Pettit Isolation, structural elucidation and synthesis of novel antineoplastic substances denominated "combretastatins"

Also Published As

Publication number Publication date
AU1371992A (en) 1992-10-21
WO1992016486A1 (en) 1992-10-01

Similar Documents

Publication Publication Date Title
GB9106177D0 (en) Substituted diphenylethylenes and analogues or derivatives thereof
GR3023258T3 (en) 3-Aryl-4-hydroxy-delta3-dihydrofuranone and 3-aryl-4-hydroxy-delta3-dihydrothiophenone derivatives
GR3023621T3 (en) 3-Hydroxy-4-aryl-5-oxo-pyrazolin derivatives
IL101865A0 (en) Thiopyranopyrrole derivatives and their preparation
EP0503301A3 (en) Peptide derivatives and application thereof
HU9203994D0 (en) Imidazo-pyridine derivatives
ZA921279B (en) Substituted alpha-aminoaldehydes and derivatives
HU9202768D0 (en) Cyano-phenyl-pyrrole derivatives
EP0482649A3 (en) Cm-chitin derivatives and use thereof
ZA92278B (en) 3-quinuclidine derivatives
HU9202388D0 (en) Aryl-alkyl-amine derivatives
EP0520435A3 (en) Dc-89 derivatives
ZA922976B (en) 4-Aryl-3-heteroarylureidoquinoline derivatives
HU9203996D0 (en) Guanidine derivatives
ZA925791B (en) Quartromicin and its derivatives and salts
HU9200011D0 (en) Trifluoro-methyl-1-carba(1-dethia)-cepheme derivatives
GB2262739B (en) Benzofuranylimidazole derivatives
GB9102423D0 (en) Pryimidinyl-and triazinylsalicyl-and-picolinylaldehyde derivatives
ZA929822B (en) Guanidine derivatives
EP0505941A3 (en) Peptifluorin and neopeptifluorin
HU9200105D0 (en) Bipiridyl derivatives
IL92606A0 (en) Sphingenine and derivatives thereof
HU9802846D0 (en) Fungicidal 2-imidalolin-5-one and 2-imidalolin-5-thione derivatives
GB9123231D0 (en) Tetrapeptide derivatives and analogues
ZA925260B (en) 3-aryl-4-hydroxy-delta3-dihydrofuranone and 3-aryl-4-hydroxy-delta3-dihydrothiophenone