ZA967870B - Novel oxidation derivatives of indolylalkylamines and their use as drugs - Google Patents

Novel oxidation derivatives of indolylalkylamines and their use as drugs

Info

Publication number
ZA967870B
ZA967870B ZA967870A ZA967870A ZA967870B ZA 967870 B ZA967870 B ZA 967870B ZA 967870 A ZA967870 A ZA 967870A ZA 967870 A ZA967870 A ZA 967870A ZA 967870 B ZA967870 B ZA 967870B
Authority
ZA
South Africa
Prior art keywords
indolylalkylamines
drugs
novel oxidation
oxidation derivatives
derivatives
Prior art date
Application number
ZA967870A
Other languages
English (en)
Inventor
Jean-Bernard Fourtillan
Marianne Fourtillan
Jean-Claude Jacquesi
Marie-Paule Jouannetaud
Bruno Violeau
Omar Karam
Original Assignee
Cemaf
Besins Iscovesco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cemaf, Besins Iscovesco filed Critical Cemaf
Publication of ZA967870B publication Critical patent/ZA967870B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Indole Compounds (AREA)
ZA967870A 1995-09-18 1996-09-18 Novel oxidation derivatives of indolylalkylamines and their use as drugs ZA967870B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9510900A FR2738818B1 (fr) 1995-09-18 1995-09-18 Nouveaux derives d'oxydation d'indolylalkylamines, et leur utilisation a titre de medicament

Publications (1)

Publication Number Publication Date
ZA967870B true ZA967870B (en) 1997-04-07

Family

ID=9482641

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA967870A ZA967870B (en) 1995-09-18 1996-09-18 Novel oxidation derivatives of indolylalkylamines and their use as drugs

Country Status (13)

Country Link
US (1) US6066663A (ja)
EP (1) EP0851856B1 (ja)
JP (1) JP3513876B2 (ja)
AR (1) AR005865A1 (ja)
AT (1) ATE210117T1 (ja)
AU (1) AU7088396A (ja)
DE (1) DE69617712T2 (ja)
DK (1) DK0851856T3 (ja)
ES (1) ES2169264T3 (ja)
FR (1) FR2738818B1 (ja)
PT (1) PT851856E (ja)
WO (1) WO1997011056A1 (ja)
ZA (1) ZA967870B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002070478A1 (en) 2001-03-06 2002-09-12 Astrazeneca Ab Indolone derivatives having vascular-damaging activity
TW200508197A (en) * 2003-03-31 2005-03-01 Ucb Sa Indolone-acetamide derivatives, processes for preparing them and their uses
FR2857011B1 (fr) * 2003-07-04 2005-09-16 Servier Lab Nouveaux derives du benzothiophene 2-thiosubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
BR102016024814A2 (pt) 2016-10-24 2018-05-08 Aché Laboratórios Farmacêuticos S.A. composto, processo de obtenção do composto, composição farmacêutica, uso do composto e método de tratamento de desordens psiquiátricas e/ou distúrbios do sono

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2680366B1 (fr) * 1991-08-13 1995-01-20 Adir Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
CZ283965B6 (cs) * 1992-08-06 1998-07-15 Warner-Lambert Company 2-thioindolové, 2-indolinthionové a polysulfidové sloučeniny, 2-selenoindolové, 2-indolinselenonové a selenidové sloučeniny a farmaceutické prostředky na jejich bázi
US5763471A (en) * 1994-04-07 1998-06-09 Cemaf Melatoninergic agonist spiro indolepyrrolidine! derivatives, process for their preparation and their use as medicinal products
FR2737725B1 (fr) * 1995-08-08 1997-10-31 Valentonine Nouveaux derives acyles de la melatonine et d'analogues melatoninergiques, leur procede de preparation et leur utilisation en tant que medicament

Also Published As

Publication number Publication date
ES2169264T3 (es) 2002-07-01
DE69617712D1 (de) 2002-01-17
JP3513876B2 (ja) 2004-03-31
EP0851856B1 (fr) 2001-12-05
PT851856E (pt) 2002-05-31
DE69617712T2 (de) 2004-05-06
FR2738818B1 (fr) 1997-12-05
AR005865A1 (es) 1999-07-21
EP0851856A1 (fr) 1998-07-08
WO1997011056A1 (fr) 1997-03-27
DK0851856T3 (da) 2002-04-02
JPH11512450A (ja) 1999-10-26
FR2738818A1 (fr) 1997-03-21
ATE210117T1 (de) 2001-12-15
AU7088396A (en) 1997-04-09
US6066663A (en) 2000-05-23

Similar Documents

Publication Publication Date Title
IL116851A0 (en) 3-arylidene-2-oxindole derivatives their preparation and use
IL118825A (en) Substituted 6-dimethylaminomethyl-1-phenyl-cyclohexane derivatives their preparation and use
PL321003A1 (en) Derivatives of piperasine, drugs containing them, their application and methods of obtaining them
IL116831A0 (en) Guanine derivatives its preparation and use
HUP9601698A3 (en) Pharmaceutical composition of adiabetical activity
HUP0000474A3 (en) Arylethenesulfonamide derivatives and drug composition containing the same
PL327737A1 (en) Carbamoyloxylic derivatives of mutiline and their application as bactericides
GB9613003D0 (en) N-oxides of morpholine derivatives and their use as therapeutic agents
ZA966494B (en) New drugs and their use
NZ321576A (en) 6-imidazol-1-ylmethyl-2-oxo-quinoline derivatives and medicaments
PL330235A1 (en) Derivatives of spiropiperidine and their application as therapeutic agents
ZA986437B (en) Derivatives of acyl-piperazinyl-pyrimidines their preparation and application as medicaments
IL118294A0 (en) Preparation of 4-aryl-piperidine derivatives
HU9502520D0 (en) Pharmaceutical use of substituted 4-phenyl-6-amino-nicotinic acid derivatives
HUP9902091A3 (en) Indolealkyl derivatives of benzodioxanmethylamine and their use as 5-ht1a receptor ligands
HUP9702241A3 (en) Use of 2-aminoindan derivatives and pharmaceutical compositions containing them
NZ300198A (en) Preparation of n-arylhydroxylamines and n-hetarylhydroxylamines
ZA96452B (en) Dematological use of vitamin d derivatives
PL319352A1 (en) Bis-(2-halogenoethyl) aminophenyl group substituted derivatives of distamycin as anticarcinogenic and antiviral drugs
IL118443A0 (en) Cycloalkane-benzylidene derivatives their preparation and use
PL323311A1 (en) Bis-oximie derivatives of triazolin and isoxazolin and their application as pesticides
ZA9410004B (en) Aminosulphonyl-phenyl-1h-pyrrole derivatives method of their preparation and their use
IL123092A0 (en) Pyrazol-4-ylbenzoyl derivatives their preparation and use
ZA967870B (en) Novel oxidation derivatives of indolylalkylamines and their use as drugs
AU4489196A (en) Novel medical use of heme products