ZA964090B - Low molecular weight bicyclic-urea type thrombin inhibitors - Google Patents

Low molecular weight bicyclic-urea type thrombin inhibitors

Info

Publication number
ZA964090B
ZA964090B ZA964090A ZA964090A ZA964090B ZA 964090 B ZA964090 B ZA 964090B ZA 964090 A ZA964090 A ZA 964090A ZA 964090 A ZA964090 A ZA 964090A ZA 964090 B ZA964090 B ZA 964090B
Authority
ZA
South Africa
Prior art keywords
molecular weight
low molecular
thrombin inhibitors
urea type
type thrombin
Prior art date
Application number
ZA964090A
Other languages
English (en)
Inventor
John Dimaio
John W Gillard
M Arshad Siddiqui
Benoit Bachand
Annette Marian Doherty
Jeremy John Edmunds
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of ZA964090B publication Critical patent/ZA964090B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA964090A 1995-05-22 1996-05-22 Low molecular weight bicyclic-urea type thrombin inhibitors ZA964090B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9510264.6A GB9510264D0 (en) 1995-05-22 1995-05-22 Low molecular weight bicyclic-urea type thrombin inhibitors

Publications (1)

Publication Number Publication Date
ZA964090B true ZA964090B (en) 1997-05-13

Family

ID=10774799

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA964090A ZA964090B (en) 1995-05-22 1996-05-22 Low molecular weight bicyclic-urea type thrombin inhibitors

Country Status (7)

Country Link
EP (1) EP0846120A1 (fr)
JP (1) JPH11505260A (fr)
AU (1) AU5682596A (fr)
CA (1) CA2218816A1 (fr)
GB (1) GB9510264D0 (fr)
WO (1) WO1996037497A1 (fr)
ZA (1) ZA964090B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998028326A1 (fr) * 1996-12-23 1998-07-02 Biochem Pharma Inc. Inhibiteurs bicycliques de thrombine
US6323219B1 (en) 1998-04-02 2001-11-27 Ortho-Mcneil Pharmaceutical, Inc. Methods for treating immunomediated inflammatory disorders
US8106094B2 (en) 1998-07-06 2012-01-31 Johnson & Johnson Consumer Companies, Inc. Compositions and methods for treating skin conditions
US8093293B2 (en) 1998-07-06 2012-01-10 Johnson & Johnson Consumer Companies, Inc. Methods for treating skin conditions
SK10742001A3 (sk) 1999-01-27 2002-08-06 Ortho-Mcneil Pharmaceutical, Inc. Peptidylové heterocyklické ketóny použiteľné ako inhibítory tryptázy
US8431550B2 (en) 2000-10-27 2013-04-30 Johnson & Johnson Consumer Companies, Inc. Topical anti-cancer compositions and methods of use thereof
US7192615B2 (en) 2001-02-28 2007-03-20 J&J Consumer Companies, Inc. Compositions containing legume products
KR20040106291A (ko) 2002-03-22 2004-12-17 지피씨 바이오테크 아게 면역억제 화합물, 이의 제조 방법 및 용도
PE20171335A1 (es) 2014-10-06 2017-09-13 Cortexyme Inc Inhibidores de gingipaina de lisina
JP6877424B2 (ja) 2015-11-09 2021-05-26 コーテクシーミー, インコーポレイテッド アルギニンジンジパインの阻害剤
BR112019004864A8 (pt) 2016-09-16 2023-03-07 Cortexyme Inc Inibidores cetona de lisina gingipain

Also Published As

Publication number Publication date
JPH11505260A (ja) 1999-05-18
GB9510264D0 (en) 1995-07-19
WO1996037497A1 (fr) 1996-11-28
AU5682596A (en) 1996-12-11
EP0846120A1 (fr) 1998-06-10
CA2218816A1 (fr) 1996-11-28

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