ZA963784B - Terpenoidic derivatives useful as antitumor agents. - Google Patents

Terpenoidic derivatives useful as antitumor agents.

Info

Publication number
ZA963784B
ZA963784B ZA9603784A ZA963784A ZA963784B ZA 963784 B ZA963784 B ZA 963784B ZA 9603784 A ZA9603784 A ZA 9603784A ZA 963784 A ZA963784 A ZA 963784A ZA 963784 B ZA963784 B ZA 963784B
Authority
ZA
South Africa
Prior art keywords
terpenoidic
antitumor agents
derivatives useful
sarcodictyins
derivatives
Prior art date
Application number
ZA9603784A
Other languages
English (en)
Inventor
Carlo Battistini
Marina Ciomei
Francesco Pietra
Michelle D Ambrosio
Antonio Guerriero
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of ZA963784B publication Critical patent/ZA963784B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9603784A 1995-05-16 1996-05-13 Terpenoidic derivatives useful as antitumor agents. ZA963784B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9509888.5A GB9509888D0 (en) 1995-05-16 1995-05-16 Terpenoidic derivatives useful as antitumour agents

Publications (1)

Publication Number Publication Date
ZA963784B true ZA963784B (en) 1997-11-13

Family

ID=10774540

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9603784A ZA963784B (en) 1995-05-16 1996-05-13 Terpenoidic derivatives useful as antitumor agents.

Country Status (23)

Country Link
US (2) US5869514A (no)
EP (1) EP0773782B1 (no)
JP (1) JPH10503218A (no)
KR (1) KR100420018B1 (no)
AT (1) ATE199641T1 (no)
AU (1) AU717028B2 (no)
CA (1) CA2194463A1 (no)
DE (1) DE69612056T2 (no)
DK (1) DK0773782T3 (no)
ES (1) ES2159357T3 (no)
GB (1) GB9509888D0 (no)
GR (1) GR3035982T3 (no)
HU (1) HUP9702443A3 (no)
IL (1) IL118218A (no)
MX (1) MX9700359A (no)
NO (1) NO312614B1 (no)
NZ (1) NZ307540A (no)
PL (1) PL183644B1 (no)
PT (1) PT773782E (no)
RU (1) RU2179441C2 (no)
UA (1) UA45974C2 (no)
WO (1) WO1996036335A1 (no)
ZA (1) ZA963784B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965718A (en) * 1997-10-24 1999-10-12 The Scripps Research Institute Analogs of sarcodictyin and eleutherobin
US6172205B1 (en) * 1997-12-11 2001-01-09 The Trustees Of Columbia In The City Of New York Synthetic process toward total synthesis of eleutherobin and its analogues and uses thereof
CA2323439A1 (en) * 1998-03-16 1999-09-23 Cytovia, Inc. Dipeptide caspase inhibitors and the use thereof
US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
CA2290316A1 (en) 1999-11-24 2001-05-24 The University Of British Columbia Novel source of eleutherobin and related antimitotic diterpenes
BR0114713A (pt) * 2000-10-16 2004-01-13 Neopharm Inc Formulação lipossÈmica de mitoxantrona
US7067494B2 (en) * 2001-06-22 2006-06-27 The University Of British Columbia Antimitotic eleuthesides
GB0122257D0 (en) * 2001-09-14 2001-11-07 Pharmacia & Upjohn Spa Simplified sarcodictyin derivatives
GB0131034D0 (en) * 2001-12-28 2002-02-13 Pharmacia & Upjohn Spa Benzocyclodecane derivatives with antitumor activity
JP4364554B2 (ja) * 2002-06-07 2009-11-18 株式会社ルネサステクノロジ スイッチング電源装置及びスイッチング電源システム

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861776A (en) * 1987-01-30 1989-08-29 Syntex (U.S.A) Inc. Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof, compositions and use
IL91542A0 (en) * 1988-10-06 1990-04-29 Erba Carlo Spa N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPH10503218A (ja) 1998-03-24
ES2159357T3 (es) 2001-10-01
ATE199641T1 (de) 2001-03-15
CA2194463A1 (en) 1996-11-21
AU717028B2 (en) 2000-03-16
HUP9702443A2 (hu) 1998-06-29
PL183644B1 (pl) 2002-06-28
IL118218A (en) 1999-10-28
NZ307540A (en) 1998-02-26
MX9700359A (es) 1997-04-30
RU2179441C2 (ru) 2002-02-20
US5922750A (en) 1999-07-13
UA45974C2 (uk) 2002-05-15
AU5691796A (en) 1996-11-29
DE69612056D1 (de) 2001-04-19
NO970178D0 (no) 1997-01-15
GB9509888D0 (en) 1995-07-12
US5869514A (en) 1999-02-09
WO1996036335A1 (en) 1996-11-21
KR100420018B1 (ko) 2004-05-31
KR970704436A (ko) 1997-09-06
NO312614B1 (no) 2002-06-10
IL118218A0 (en) 1996-09-12
GR3035982T3 (en) 2001-08-31
DE69612056T2 (de) 2001-08-23
EP0773782A1 (en) 1997-05-21
NO970178L (no) 1997-01-15
HUP9702443A3 (en) 2000-08-28
EP0773782B1 (en) 2001-03-14
PT773782E (pt) 2001-08-30
PL318130A1 (en) 1997-05-12
DK0773782T3 (da) 2001-06-25

Similar Documents

Publication Publication Date Title
UA39158C2 (uk) Похідні n4-оксикарбоніл-5'-дезокси-5-фторцитидину та фармацевтичний препарат на їх основі
MX9703621A (es) Nuevos derivados aminoacidos con actividad mejorada para la resistencia a drogas multiples.
HK1039328A1 (en) Pyrazolopyrimidinone derivatives for the treatment of impotence
BG101118A (en) Therapeutical compounds
BG103417A (en) Condensed pyrimidine bicyclic derivatives
YU60900A (sh) Novi kristalni oblici antivirusnog benzimidazolskog jedinjenja
PL329802A1 (en) Derivatives of androstene
NZ308789A (en) Tetralin derivatives and medicaments
HRP930239A2 (en) Anti-inflamatory 4-aminophenol derivatives
HK1024177A1 (en) Cytotoxic amino sugar and related sugar derivatives of indolopyrrolocarbazoles
MX9602973A (es) Uso de un antagonista de bradiquinina en una composicion, cosmetica, farmaceutica o dermatologica y la composicion obtenida.
MY115211A (en) Novel amino acid derivatives, their preparation and use
BG102250A (en) The use of marigold-extracted glycosides for the treatment of psoriasis
ZA963784B (en) Terpenoidic derivatives useful as antitumor agents.
GR3033253T3 (en) Tri(platinum) complexes
TR200100637T2 (tr) Yeni doğal ürün türevleri
ES2016464A6 (es) Procedimiento para preparar derivados de 2', 5' -oligoadenilato.
GB9505082D0 (en) Medicament
TW374085B (en) Novel piperidine derivatives, their preparation, pharmaceutical formulation and medical use
MX9702671A (es) Derivados metalocenicos de diariletileno, metodos de preparacion y composiciones farmaceuticas que contienen estos derivados.
MY111746A (en) Therapeutic nucleosides.
NZ268039A (en) Use of efaroxan in treating parkinson's disease
HUP0101602A2 (hu) Termékenységet javító készítmény, és annak alkalmazása
HUP9801985A3 (en) Use of cystine derivatives for the preparation of pharmaceutical compositions useful for the treatment of restenosis
JO1708B1 (en) The use of trinitrobenzene or cochineal acid in the treatment of cancer or genital diseases