ZA962707B - New inhibitor of the erythrina caffra type and its use to purity serine proteases. - Google Patents

New inhibitor of the erythrina caffra type and its use to purity serine proteases.

Info

Publication number
ZA962707B
ZA962707B ZA9602707A ZA962707A ZA962707B ZA 962707 B ZA962707 B ZA 962707B ZA 9602707 A ZA9602707 A ZA 9602707A ZA 962707 A ZA962707 A ZA 962707A ZA 962707 B ZA962707 B ZA 962707B
Authority
ZA
South Africa
Prior art keywords
polypeptide
seq
serine proteases
plasminogen activators
purity
Prior art date
Application number
ZA9602707A
Other languages
English (en)
Inventor
Ulrich Kohnert
Anne Stern
Manfred Wozny
Stephan Fischer
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA962707B publication Critical patent/ZA962707B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9602707A 1995-04-06 1996-04-04 New inhibitor of the erythrina caffra type and its use to purity serine proteases. ZA962707B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19512937A DE19512937A1 (de) 1995-04-06 1995-04-06 Neuer Inhibitor des Erythrina caffra Typs und dessen Verwendung zur Reinigung von Serinproteasen

Publications (1)

Publication Number Publication Date
ZA962707B true ZA962707B (en) 1997-10-06

Family

ID=7758967

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9602707A ZA962707B (en) 1995-04-06 1996-04-04 New inhibitor of the erythrina caffra type and its use to purity serine proteases.

Country Status (12)

Country Link
US (1) US5973118A (ja)
EP (1) EP0819173B1 (ja)
JP (1) JP3061199B2 (ja)
AT (1) ATE266096T1 (ja)
AU (1) AU5275496A (ja)
CA (1) CA2215531C (ja)
DE (2) DE19512937A1 (ja)
DK (1) DK0819173T3 (ja)
ES (1) ES2219685T3 (ja)
IL (1) IL117761A (ja)
WO (1) WO1996031606A1 (ja)
ZA (1) ZA962707B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3626982B2 (ja) * 1997-08-29 2005-03-09 アークレイ株式会社 タンパク質分解酵素阻害物質の測定方法およびそれに用いる測定キット
AU3959499A (en) * 1998-05-28 1999-12-13 Korea Green Cross Corporation Process of purifying angiogenesis inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3689927T3 (de) * 1985-10-04 1998-10-22 South African Inventions Reagens und Verfahren.

Also Published As

Publication number Publication date
US5973118A (en) 1999-10-26
CA2215531C (en) 2001-12-18
DE59611005D1 (de) 2004-06-09
EP0819173A1 (de) 1998-01-21
JPH10505758A (ja) 1998-06-09
ATE266096T1 (de) 2004-05-15
JP3061199B2 (ja) 2000-07-10
ES2219685T3 (es) 2004-12-01
WO1996031606A1 (de) 1996-10-10
DE19512937A1 (de) 1996-10-10
MX9707486A (es) 1997-11-29
IL117761A0 (en) 1996-08-04
CA2215531A1 (en) 1996-10-10
IL117761A (en) 2004-06-20
AU5275496A (en) 1996-10-23
DK0819173T3 (da) 2004-09-13
EP0819173B1 (de) 2004-05-06

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