ZA9610853B - Processes and intermediates for preparing pharmaceuticals. - Google Patents

Processes and intermediates for preparing pharmaceuticals.

Info

Publication number
ZA9610853B
ZA9610853B ZA9610853A ZA9610853A ZA9610853B ZA 9610853 B ZA9610853 B ZA 9610853B ZA 9610853 A ZA9610853 A ZA 9610853A ZA 9610853 A ZA9610853 A ZA 9610853A ZA 9610853 B ZA9610853 B ZA 9610853B
Authority
ZA
South Africa
Prior art keywords
intermediates
processes
preparing pharmaceuticals
pharmaceuticals
preparing
Prior art date
Application number
ZA9610853A
Other languages
English (en)
Inventor
Stephen K Etridge
Jerome Hayes
Andrew S Wells
Timothy Charles Walsgrove
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA9610853B publication Critical patent/ZA9610853B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA9610853A 1995-12-29 1996-12-23 Processes and intermediates for preparing pharmaceuticals. ZA9610853B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US953195P 1995-12-29 1995-12-29

Publications (1)

Publication Number Publication Date
ZA9610853B true ZA9610853B (en) 1998-04-06

Family

ID=21738230

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9610853A ZA9610853B (en) 1995-12-29 1996-12-23 Processes and intermediates for preparing pharmaceuticals.

Country Status (20)

Country Link
US (1) US6225465B1 (ja)
EP (1) EP1019383A2 (ja)
JP (1) JP2000502353A (ja)
KR (1) KR19990076827A (ja)
CN (1) CN1214045A (ja)
AR (1) AR005284A1 (ja)
AU (1) AU722207B2 (ja)
BR (1) BR9612372A (ja)
CA (1) CA2241759A1 (ja)
CZ (1) CZ206598A3 (ja)
HU (1) HUP9904064A3 (ja)
IL (1) IL125032A0 (ja)
MX (1) MX9805358A (ja)
NO (1) NO983006L (ja)
NZ (1) NZ326866A (ja)
PL (1) PL327603A1 (ja)
TR (1) TR199801250T2 (ja)
TW (1) TW402593B (ja)
WO (1) WO1997024336A2 (ja)
ZA (1) ZA9610853B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1209063A (zh) * 1995-12-29 1999-02-24 史密丝克莱恩比彻姆公司 玻连蛋白受体拮抗剂
KR19990076876A (ko) * 1995-12-29 1999-10-25 스티븐 베네티아너 비트로넥틴 수용체 길항제
US6420558B1 (en) 1998-04-09 2002-07-16 Meiji Seika Kaisha, Ltd. Aminopiperidine derivates as integrin αvβ3 antagonists
WO2001010844A1 (en) 1999-08-05 2001-02-15 Meiji Seika Kaisha, Ltd. φ-AMINO-α-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN αvβ3 ANTAGONISM
EP1229913A4 (en) 1999-11-18 2005-01-19 Antexpharma Inc SUBSTITUTED 1-BENZAZEPINE AND THEIR DERIVATIVES
DK2251319T3 (da) * 2005-09-02 2012-03-05 Otsuka Pharma Co Ltd Fremgangsmåde til fremstilling af derivater af benzoesyre
CN111683976B (zh) 2018-02-05 2022-11-18 生物辐射实验室股份有限公司 具有阴离子交换-疏水混合模式配体的色谱树脂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039820A (en) 1990-02-26 1991-08-13 Eli Lilly And Company 4-amino-6-iodo-hexahydrobenz(cd)indoles
BR9200951A (pt) * 1991-03-21 1992-11-17 Hoffmann La Roche Compostos, processo para sua producao,preparacoes farmaceuticas e uso
PT100631B (pt) 1991-06-28 1999-06-30 Smithkline Beecham Corp Antagonistas biciclicos de fibrinogenio, seu uso e composicoes farmaceuticas que os contem
HUT71819A (en) 1992-11-09 1996-02-28 Boots Co Plc 1,4-benzothiazepine derivatives and pharmaceutical compositions containing them
MA23420A1 (fr) 1994-01-07 1995-10-01 Smithkline Beecham Corp Antagonistes bicycliques de fibrinogene.
US5977101A (en) * 1995-06-29 1999-11-02 Smithkline Beecham Corporation Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity

Also Published As

Publication number Publication date
AR005284A1 (es) 1999-04-28
JP2000502353A (ja) 2000-02-29
NZ326866A (en) 2000-01-28
KR19990076827A (ko) 1999-10-25
WO1997024336A2 (en) 1997-07-10
CZ206598A3 (cs) 1998-12-16
CN1214045A (zh) 1999-04-14
HUP9904064A3 (en) 2002-03-28
PL327603A1 (en) 1998-12-21
NO983006D0 (no) 1998-06-26
AU1554097A (en) 1997-07-28
CA2241759A1 (en) 1997-07-10
AU722207B2 (en) 2000-07-27
WO1997024336A3 (en) 1997-08-21
MX9805358A (es) 1998-10-31
NO983006L (no) 1998-08-26
HUP9904064A2 (hu) 2000-05-28
BR9612372A (pt) 1999-07-13
IL125032A0 (en) 1999-01-26
TW402593B (en) 2000-08-21
EP1019383A2 (en) 2000-07-19
US6225465B1 (en) 2001-05-01
TR199801250T2 (xx) 1998-10-21

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