ZA959326B - Phosphonosulfonate squalene synthetase inhibitor salts and method - Google Patents
Phosphonosulfonate squalene synthetase inhibitor salts and methodInfo
- Publication number
- ZA959326B ZA959326B ZA959326A ZA959326A ZA959326B ZA 959326 B ZA959326 B ZA 959326B ZA 959326 A ZA959326 A ZA 959326A ZA 959326 A ZA959326 A ZA 959326A ZA 959326 B ZA959326 B ZA 959326B
- Authority
- ZA
- South Africa
- Prior art keywords
- squalene synthetase
- synthetase inhibitor
- inhibitor salts
- phosphonosulfonate
- phosphonosulfonate squalene
- Prior art date
Links
- LQHYUUBBIJGBNR-UHFFFAOYSA-N OP(O)(=O)S(O)(=O)=O Chemical compound OP(O)(=O)S(O)(=O)=O LQHYUUBBIJGBNR-UHFFFAOYSA-N 0.000 title 1
- 229940123495 Squalene synthetase inhibitor Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 239000004059 squalene synthase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4075—Esters with hydroxyalkyl compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33366194A | 1994-11-03 | 1994-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA959326B true ZA959326B (en) | 1997-05-05 |
Family
ID=23303735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA959326A ZA959326B (en) | 1994-11-03 | 1995-11-03 | Phosphonosulfonate squalene synthetase inhibitor salts and method |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0710665A1 (cs) |
| JP (1) | JPH08208672A (cs) |
| KR (1) | KR960017680A (cs) |
| CN (1) | CN1130188A (cs) |
| AU (1) | AU3458795A (cs) |
| CA (1) | CA2159850A1 (cs) |
| CZ (1) | CZ279595A3 (cs) |
| FI (1) | FI955256A (cs) |
| HU (1) | HUT73140A (cs) |
| IL (1) | IL115537A0 (cs) |
| NO (1) | NO954389L (cs) |
| PL (1) | PL311218A1 (cs) |
| TW (1) | TW318852B (cs) |
| ZA (1) | ZA959326B (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2780974B1 (fr) * | 1998-07-08 | 2001-09-28 | Sod Conseils Rech Applic | Utilisation de derives d'imidazopyrazines pour preparer un medicament destine a traiter les pathologies qui resultent de la formation de la proteine g heterotrimetrique |
| WO2002038180A1 (fr) * | 2000-11-09 | 2002-05-16 | Takeda Chemical Industries, Ltd. | Agent haute densite faisant monter le taux de lipoproteine-cholesterol |
| WO2007075186A2 (en) | 2005-04-18 | 2007-07-05 | The Regents Of The University Of California | Antimicrobial therapy for bacterial infections |
| JP5161872B2 (ja) * | 2006-05-12 | 2013-03-13 | ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア | 細菌感染に対する抗微生物療法 |
| CN101580472B (zh) * | 2009-06-24 | 2013-07-10 | 广西壮族自治区化工研究院 | 1,1'-联-2-萘酚的拆分剂以及拆分方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2107644A1 (en) * | 1992-10-28 | 1994-04-29 | David R. Magnin | .alpha.-phosphonosulfonae squalene synthetase inhibitors and methd |
| US5312814A (en) * | 1992-12-09 | 1994-05-17 | Bristol-Myers Squibb Co. | α-phosphonocarboxylate squalene synthetase inhibitors |
-
1995
- 1995-10-04 CA CA002159850A patent/CA2159850A1/en not_active Abandoned
- 1995-10-06 IL IL11553795A patent/IL115537A0/xx unknown
- 1995-10-25 CZ CZ952795A patent/CZ279595A3/cs unknown
- 1995-10-26 EP EP95307618A patent/EP0710665A1/en not_active Withdrawn
- 1995-10-27 JP JP7280397A patent/JPH08208672A/ja active Pending
- 1995-11-02 PL PL95311218A patent/PL311218A1/xx unknown
- 1995-11-02 NO NO954389A patent/NO954389L/no unknown
- 1995-11-02 AU AU34587/95A patent/AU3458795A/en not_active Abandoned
- 1995-11-02 TW TW084111593A patent/TW318852B/zh active
- 1995-11-02 FI FI955256A patent/FI955256A/fi not_active Application Discontinuation
- 1995-11-02 HU HU9503136A patent/HUT73140A/hu unknown
- 1995-11-03 CN CN95119023A patent/CN1130188A/zh active Pending
- 1995-11-03 ZA ZA959326A patent/ZA959326B/xx unknown
- 1995-11-03 KR KR1019950039576A patent/KR960017680A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR960017680A (ko) | 1996-06-17 |
| CZ279595A3 (en) | 1996-08-14 |
| NO954389D0 (no) | 1995-11-02 |
| IL115537A0 (en) | 1996-01-19 |
| JPH08208672A (ja) | 1996-08-13 |
| CN1130188A (zh) | 1996-09-04 |
| NO954389L (no) | 1996-05-06 |
| HU9503136D0 (en) | 1995-12-28 |
| CA2159850A1 (en) | 1996-05-04 |
| HUT73140A (en) | 1996-06-28 |
| PL311218A1 (en) | 1996-05-13 |
| FI955256A (fi) | 1996-05-04 |
| AU3458795A (en) | 1996-05-09 |
| EP0710665A1 (en) | 1996-05-08 |
| TW318852B (cs) | 1997-11-01 |
| FI955256A0 (fi) | 1995-11-02 |
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