ZA954306B - Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1h-indole-3-carboxylic acid - Google Patents
Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1h-indole-3-carboxylic acidInfo
- Publication number
- ZA954306B ZA954306B ZA954306A ZA954306A ZA954306B ZA 954306 B ZA954306 B ZA 954306B ZA 954306 A ZA954306 A ZA 954306A ZA 954306 A ZA954306 A ZA 954306A ZA 954306 B ZA954306 B ZA 954306B
- Authority
- ZA
- South Africa
- Prior art keywords
- tetrazol
- ylmethyl
- indole
- biphenyl
- butyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/250,397 US5412102A (en) | 1994-05-27 | 1994-05-27 | Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA954306B true ZA954306B (en) | 1996-11-26 |
Family
ID=22947567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA954306A ZA954306B (en) | 1994-05-27 | 1995-05-26 | Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1h-indole-3-carboxylic acid |
Country Status (10)
Country | Link |
---|---|
US (3) | US5412102A (xx) |
EP (1) | EP0760815A1 (xx) |
JP (1) | JPH10501230A (xx) |
CN (1) | CN1070193C (xx) |
AU (1) | AU2643995A (xx) |
BR (1) | BR9507771A (xx) |
CA (1) | CA2191576A1 (xx) |
IL (1) | IL113876A (xx) |
WO (1) | WO1995032962A1 (xx) |
ZA (1) | ZA954306B (xx) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0222056D0 (en) * | 2002-09-23 | 2002-10-30 | Novartis Ag | Process for the manufacture of organic compounds |
AU2007234598B2 (en) * | 2002-09-23 | 2010-03-04 | Novartis Ag | Process for the manufacture of Valsartan |
ITMI20032338A1 (it) * | 2003-11-28 | 2005-05-29 | Dinamite Dipharma S P A In Forma A Bbreviata Diph | Composti feniltetrazolici. |
CA2552087C (en) * | 2004-01-30 | 2011-01-25 | Euro-Celtique S.A. | Methods for making 4-tetrazolyl-4-phenylpiperidine compounds |
WO2006029056A1 (en) | 2004-09-02 | 2006-03-16 | Teva Pharmaceutical Industries Ltd. | Preparation of olmesartan medoxomil |
JP2007525504A (ja) * | 2004-12-30 | 2007-09-06 | テバ ファーマシューティカル インダストリーズ リミティド | 2.5よりも高いpHでオルメサルタンメドキソミルを調製するための方法 |
CA2592160A1 (en) | 2005-01-03 | 2006-07-13 | Teva Pharmaceutical Industries Ltd. | Olmesartan medoxomil with reduced levels of impurities |
AR070176A1 (es) * | 2008-01-17 | 2010-03-17 | Novartis Ag | Procesos de sintesis de inhibidores de nep, compuestos intermediarios y uso de los mismos en la sintesis |
US8835668B2 (en) | 2010-08-23 | 2014-09-16 | Novartis Ag | Process for the preparation of intermediates for the manufacture of NEP inhibitors |
CN102432558B (zh) * | 2011-11-10 | 2014-04-09 | 浙江天宇药业股份有限公司 | 一种合成厄贝沙坦及其中间体的方法 |
CN103554048A (zh) * | 2013-10-23 | 2014-02-05 | 安徽省郎溪县联科实业有限公司 | 一种2-异丙苯基-5-苯基四氮唑的制备方法 |
US20170174614A1 (en) | 2015-12-22 | 2017-06-22 | Zogenix International Limited | Metabolism resistant fenfluramine analogs and methods of using the same |
US10351509B2 (en) | 2015-12-22 | 2019-07-16 | Zogenix International Limited | Fenfluramine compositions and methods of preparing the same |
CA3032996A1 (en) | 2016-08-24 | 2018-03-01 | Zogenix International Limited | Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same |
US10682317B2 (en) | 2017-09-26 | 2020-06-16 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
EP3790537A1 (en) | 2018-05-11 | 2021-03-17 | Zogenix International Limited | Compositions and methods for treating seizure-induced sudden death |
US11612574B2 (en) | 2020-07-17 | 2023-03-28 | Zogenix International Limited | Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4333943A (en) * | 1980-04-24 | 1982-06-08 | Miles Laboratories, Inc. | Ethyl 3-(3-indolyl)-3-(5-tetrazolyl) propionate compounds used as anti-hypertensive agents |
US5093346A (en) * | 1988-01-07 | 1992-03-03 | E. I. Du Pont De Nemours And Company | Substituted 1,2,4-triazole angiotensin II antagonists |
US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
US4880804A (en) * | 1988-01-07 | 1989-11-14 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking benzimidazoles |
CA2016710A1 (en) * | 1989-05-15 | 1990-11-15 | Prasun K. Chakravarty | Substituted benzimidazoles as angiotensin ii antagonists |
US5053329A (en) * | 1990-07-05 | 1991-10-01 | Merck & Co., Inc. | Process for preparation of novel angiotensin II antagonists |
US5124335A (en) * | 1991-01-30 | 1992-06-23 | Merck & Co., Inc. | Substituted pyrollo-fused 6 membered heterocycles as angiotensin ii antagonists |
AU1625192A (en) * | 1991-05-31 | 1992-12-03 | Zeneca Limited | Heterocyclic derivatives |
EP0550313A1 (fr) * | 1991-12-30 | 1993-07-07 | Synthelabo | Nouveaux dérivés de 2-(tétrazol-5-yl)-(1,1'-biphényle), leur préparation et leur utilisation comme intermédiaires de synthèse |
US5212195A (en) * | 1992-05-13 | 1993-05-18 | Syntex (U.S.A.) Inc. | Substituted indole antagonists derivatives which are angiotensin II |
-
1994
- 1994-05-27 US US08/250,397 patent/US5412102A/en not_active Expired - Fee Related
-
1995
- 1995-01-17 US US08/373,677 patent/US5446121A/en not_active Expired - Fee Related
- 1995-05-12 US US08/440,040 patent/US5527918A/en not_active Expired - Fee Related
- 1995-05-26 AU AU26439/95A patent/AU2643995A/en not_active Abandoned
- 1995-05-26 CA CA002191576A patent/CA2191576A1/en not_active Abandoned
- 1995-05-26 WO PCT/US1995/006432 patent/WO1995032962A1/en not_active Application Discontinuation
- 1995-05-26 EP EP95921335A patent/EP0760815A1/en not_active Withdrawn
- 1995-05-26 IL IL11387695A patent/IL113876A/xx not_active IP Right Cessation
- 1995-05-26 CN CN95193255A patent/CN1070193C/zh not_active Expired - Fee Related
- 1995-05-26 BR BR9507771A patent/BR9507771A/pt not_active Application Discontinuation
- 1995-05-26 JP JP8500982A patent/JPH10501230A/ja active Pending
- 1995-05-26 ZA ZA954306A patent/ZA954306B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US5412102A (en) | 1995-05-02 |
AU2643995A (en) | 1995-12-21 |
US5527918A (en) | 1996-06-18 |
IL113876A (en) | 2001-08-26 |
CA2191576A1 (en) | 1995-12-07 |
CN1149293A (zh) | 1997-05-07 |
EP0760815A1 (en) | 1997-03-12 |
WO1995032962A1 (en) | 1995-12-07 |
US5446121A (en) | 1995-08-29 |
CN1070193C (zh) | 2001-08-29 |
JPH10501230A (ja) | 1998-02-03 |
BR9507771A (pt) | 1997-08-19 |
IL113876A0 (en) | 1995-08-31 |
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