ZA952285B - Hypocholesterolemic antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide derivatives - Google Patents
Hypocholesterolemic antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide derivativesInfo
- Publication number
- ZA952285B ZA952285B ZA952285A ZA952285A ZA952285B ZA 952285 B ZA952285 B ZA 952285B ZA 952285 A ZA952285 A ZA 952285A ZA 952285 A ZA952285 A ZA 952285A ZA 952285 B ZA952285 B ZA 952285B
- Authority
- ZA
- South Africa
- Prior art keywords
- hypotriglyceridemic
- antiatherosclerotic
- hypocholesterolemic
- mercaptoacetylamide
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/217,781 US5484783A (en) | 1994-03-24 | 1994-03-24 | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA952285B true ZA952285B (en) | 1996-01-09 |
Family
ID=22812484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA952285A ZA952285B (en) | 1994-03-24 | 1995-03-20 | Hypocholesterolemic antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide derivatives |
Country Status (20)
Country | Link |
---|---|
US (1) | US5484783A (xx) |
EP (1) | EP0751775B1 (xx) |
JP (1) | JPH09510220A (xx) |
KR (1) | KR970701550A (xx) |
CN (1) | CN1144483A (xx) |
AT (1) | ATE217527T1 (xx) |
AU (1) | AU705029B2 (xx) |
CA (1) | CA2184693C (xx) |
DE (1) | DE69526731T2 (xx) |
DK (1) | DK0751775T3 (xx) |
ES (1) | ES2173180T3 (xx) |
FI (1) | FI118414B (xx) |
HU (1) | HU226643B1 (xx) |
IL (1) | IL113074A (xx) |
NO (1) | NO313176B1 (xx) |
NZ (1) | NZ282949A (xx) |
PT (1) | PT751775E (xx) |
TW (1) | TW323954B (xx) |
WO (1) | WO1995025548A2 (xx) |
ZA (1) | ZA952285B (xx) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6635632B1 (en) | 1996-12-23 | 2003-10-21 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US5834353A (en) * | 1997-10-20 | 1998-11-10 | Texas Instruments-Acer Incorporated | Method of making deep sub-micron meter MOSFET with a high permitivity gate dielectric |
US6378430B1 (en) | 1999-10-15 | 2002-04-30 | King Press Corporation | Cylinder with plate gripping device |
DE10229180A1 (de) * | 2002-06-28 | 2004-01-29 | Aventis Pharma Deutschland Gmbh | Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen |
DK1670768T3 (da) * | 2003-10-08 | 2009-11-09 | Lilly Co Eli | Forbindelser og fremgangsmåder til at behandle dyslipidæmi |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3334095A (en) * | 1965-02-16 | 1967-08-01 | Sandoz Ag | Novel pyrrolo-oxazines and pyrrolo-oxazoles |
US3334091A (en) * | 1965-03-25 | 1967-08-01 | Sandoz Ag | Sedatives |
GB1525845A (en) * | 1976-07-30 | 1978-09-20 | Ucb Sa | 1,2,4,5-tetrahydro-3h-2-benzazepin-3-ones |
IE50839B1 (en) * | 1980-02-26 | 1986-07-23 | Wyeth John & Brother Ltd | Novel processes for preparing proline derivatives and analogous compounds |
EP0042100A1 (de) * | 1980-06-13 | 1981-12-23 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel |
US4320057A (en) * | 1980-06-23 | 1982-03-16 | American Home Products Corporation | Aryl--pyrrolo--thiazepin--diones and aryl--piperidino--thiazepin--diones |
US4415496A (en) * | 1981-03-23 | 1983-11-15 | Merck & Co., Inc. | Bicyclic lactams |
ZA833214B (en) * | 1982-05-12 | 1983-12-28 | Hoffmann La Roche | Bicyclic compounds |
GB2128984B (en) * | 1982-05-12 | 1985-05-22 | Hoffmann La Roche | Diaza-bicyclic compounds |
US4552889A (en) * | 1983-06-09 | 1985-11-12 | Eli Lilly And Company | 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension |
US4692438A (en) * | 1984-08-24 | 1987-09-08 | Hoffmann-La Roche Inc. | Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity |
US4584294A (en) * | 1984-11-07 | 1986-04-22 | Merck & Co., Inc. | Fused tricyclic lactams as angiotensin converting enzyme inhibitors and as antihypertensive agents |
HUT40660A (en) * | 1985-04-30 | 1987-01-28 | Lilly Co Eli | Process for production of derivatives of 7-substituated bicyclic pirasilididone |
ZA874107B (xx) * | 1986-06-13 | 1987-12-09 | ||
ZA874106B (en) * | 1986-06-13 | 1987-12-08 | Merrell Dow Pharmaceuticals Inc. | Novel antihypertensive agent |
US4973585A (en) * | 1986-06-13 | 1990-11-27 | Merrell Dow Pharmaceuticals | Tricyclic lactams active as antihypertensive agents |
GB8629875D0 (en) * | 1986-12-15 | 1987-01-28 | Hoffmann La Roche | Pyridazodiazepine derivatives |
US4824832A (en) * | 1987-12-30 | 1989-04-25 | Merrell Dow Pharmaceuticals Inc. | Sulfhydryl containing tricyclic lactams and their pharmacological methods of use |
US5061694A (en) * | 1989-10-23 | 1991-10-29 | E. R. Squibb & Sons, Inc. | Method for stabilizing or causing regression of atherosclerosis in coronary arteries employing an ace inhibitor |
GB8926512D0 (en) * | 1989-11-23 | 1990-01-10 | Pfizer Ltd | Therapeutic agents |
AU7168091A (en) * | 1989-12-22 | 1991-07-24 | Schering Corporation | Mercaptocycloacyl aminoacid endopeptidase inhibitors |
CA2053340C (en) * | 1990-10-18 | 2002-04-02 | Timothy P. Burkholder | Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
CA2057786C (en) * | 1990-12-21 | 2002-06-18 | Gary A. Flynn | Amino and nitro containing tricyclic compounds useful as inhibitors or ace |
US5208230A (en) * | 1990-12-21 | 1993-05-04 | Merrell Dow Pharmaceuticals | Amino and nitro containing tricyclic compounds useful as inhibitors of ACE |
FR2679564A1 (fr) * | 1991-07-23 | 1993-01-29 | Inst Nat Sante Rech Med | Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent. |
EP0533084A1 (en) * | 1991-09-16 | 1993-03-24 | Schering Corporation | Pharmaceutical compositions comprising natriuretic peptides or neutral endopeptidase inhibitors for treating and preventing myointimal proliferation |
RU2124503C1 (ru) * | 1992-05-18 | 1999-01-10 | И.Р.Сквибб энд Санз, Инк. | Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция |
US5238932A (en) * | 1992-05-20 | 1993-08-24 | Merrell Dow Pharmaceuticals Inc. | Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase |
-
1994
- 1994-03-24 US US08/217,781 patent/US5484783A/en not_active Expired - Lifetime
-
1995
- 1995-02-28 ES ES95913501T patent/ES2173180T3/es not_active Expired - Lifetime
- 1995-02-28 DE DE69526731T patent/DE69526731T2/de not_active Expired - Lifetime
- 1995-02-28 KR KR1019960705294A patent/KR970701550A/ko not_active Application Discontinuation
- 1995-02-28 NZ NZ282949A patent/NZ282949A/en not_active IP Right Cessation
- 1995-02-28 AU AU20914/95A patent/AU705029B2/en not_active Ceased
- 1995-02-28 EP EP95913501A patent/EP0751775B1/en not_active Expired - Lifetime
- 1995-02-28 CA CA002184693A patent/CA2184693C/en not_active Expired - Fee Related
- 1995-02-28 HU HU9602603A patent/HU226643B1/hu not_active IP Right Cessation
- 1995-02-28 PT PT95913501T patent/PT751775E/pt unknown
- 1995-02-28 CN CN95192242A patent/CN1144483A/zh active Pending
- 1995-02-28 WO PCT/US1995/002476 patent/WO1995025548A2/en active IP Right Grant
- 1995-02-28 JP JP7523719A patent/JPH09510220A/ja active Pending
- 1995-02-28 AT AT95913501T patent/ATE217527T1/de active
- 1995-02-28 DK DK95913501T patent/DK0751775T3/da active
- 1995-03-20 ZA ZA952285A patent/ZA952285B/xx unknown
- 1995-03-21 TW TW084102716A patent/TW323954B/zh not_active IP Right Cessation
- 1995-03-22 IL IL11307495A patent/IL113074A/xx not_active IP Right Cessation
-
1996
- 1996-09-23 NO NO19963989A patent/NO313176B1/no not_active IP Right Cessation
- 1996-09-23 FI FI963785A patent/FI118414B/fi not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5484783A (en) | 1996-01-16 |
ES2173180T3 (es) | 2002-10-16 |
CA2184693A1 (en) | 1995-09-28 |
HU9602603D0 (en) | 1996-11-28 |
NZ282949A (en) | 1997-07-27 |
WO1995025548A2 (en) | 1995-09-28 |
PT751775E (pt) | 2002-10-31 |
CN1144483A (zh) | 1997-03-05 |
EP0751775A1 (en) | 1997-01-08 |
FI963785A (fi) | 1996-09-23 |
FI963785A0 (fi) | 1996-09-23 |
FI118414B (fi) | 2007-11-15 |
EP0751775B1 (en) | 2002-05-15 |
IL113074A0 (en) | 1995-06-29 |
HUT74886A (en) | 1997-02-28 |
AU2091495A (en) | 1995-10-09 |
DE69526731D1 (en) | 2002-06-20 |
DK0751775T3 (da) | 2002-08-26 |
JPH09510220A (ja) | 1997-10-14 |
NO313176B1 (no) | 2002-08-26 |
CA2184693C (en) | 2001-01-02 |
HU226643B1 (en) | 2009-05-28 |
DE69526731T2 (de) | 2003-02-06 |
AU705029B2 (en) | 1999-05-13 |
TW323954B (en) | 1998-01-01 |
NO963989D0 (no) | 1996-09-23 |
IL113074A (en) | 2000-07-26 |
WO1995025548A3 (en) | 1995-11-09 |
NO963989L (no) | 1996-11-22 |
KR970701550A (ko) | 1997-04-12 |
ATE217527T1 (de) | 2002-06-15 |
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