NO963989D0 - Hypokolesterolemiske-, antiatherosklerotiske- og hypotriglyceridemiske mercaptoacetylamidderivater - Google Patents

Hypokolesterolemiske-, antiatherosklerotiske- og hypotriglyceridemiske mercaptoacetylamidderivater

Info

Publication number
NO963989D0
NO963989D0 NO963989A NO963989A NO963989D0 NO 963989 D0 NO963989 D0 NO 963989D0 NO 963989 A NO963989 A NO 963989A NO 963989 A NO963989 A NO 963989A NO 963989 D0 NO963989 D0 NO 963989D0
Authority
NO
Norway
Prior art keywords
hypotriglyceridemic
antiatherosclerotic
hypocholesterolemic
mercaptoacetylamide
derivatives
Prior art date
Application number
NO963989A
Other languages
English (en)
Other versions
NO313176B1 (no
NO963989L (no
Inventor
Gary Alan Flynn
John Fitzhugh French
Richard Cyrus Dage
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of NO963989D0 publication Critical patent/NO963989D0/no
Publication of NO963989L publication Critical patent/NO963989L/no
Publication of NO313176B1 publication Critical patent/NO313176B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Artificial Filaments (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
NO19963989A 1994-03-24 1996-09-23 Anvendelse av merkaptoacetylamidderivater for fremstilling av et farmasöytisk preparat for behandling av hyperkolesterolemi NO313176B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/217,781 US5484783A (en) 1994-03-24 1994-03-24 Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives
PCT/US1995/002476 WO1995025548A2 (en) 1994-03-24 1995-02-28 Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide derivatives

Publications (3)

Publication Number Publication Date
NO963989D0 true NO963989D0 (no) 1996-09-23
NO963989L NO963989L (no) 1996-11-22
NO313176B1 NO313176B1 (no) 2002-08-26

Family

ID=22812484

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19963989A NO313176B1 (no) 1994-03-24 1996-09-23 Anvendelse av merkaptoacetylamidderivater for fremstilling av et farmasöytisk preparat for behandling av hyperkolesterolemi

Country Status (20)

Country Link
US (1) US5484783A (no)
EP (1) EP0751775B1 (no)
JP (1) JPH09510220A (no)
KR (1) KR970701550A (no)
CN (1) CN1144483A (no)
AT (1) ATE217527T1 (no)
AU (1) AU705029B2 (no)
CA (1) CA2184693C (no)
DE (1) DE69526731T2 (no)
DK (1) DK0751775T3 (no)
ES (1) ES2173180T3 (no)
FI (1) FI118414B (no)
HU (1) HU226643B1 (no)
IL (1) IL113074A (no)
NO (1) NO313176B1 (no)
NZ (1) NZ282949A (no)
PT (1) PT751775E (no)
TW (1) TW323954B (no)
WO (1) WO1995025548A2 (no)
ZA (1) ZA952285B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6635632B1 (en) 1996-12-23 2003-10-21 Athena Neurosciences, Inc. Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US5834353A (en) * 1997-10-20 1998-11-10 Texas Instruments-Acer Incorporated Method of making deep sub-micron meter MOSFET with a high permitivity gate dielectric
US6378430B1 (en) 1999-10-15 2002-04-30 King Press Corporation Cylinder with plate gripping device
DE10229180A1 (de) * 2002-06-28 2004-01-29 Aventis Pharma Deutschland Gmbh Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen
DK1670768T3 (da) * 2003-10-08 2009-11-09 Lilly Co Eli Forbindelser og fremgangsmåder til at behandle dyslipidæmi

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334095A (en) * 1965-02-16 1967-08-01 Sandoz Ag Novel pyrrolo-oxazines and pyrrolo-oxazoles
US3334091A (en) * 1965-03-25 1967-08-01 Sandoz Ag Sedatives
GB1525845A (en) * 1976-07-30 1978-09-20 Ucb Sa 1,2,4,5-tetrahydro-3h-2-benzazepin-3-ones
IE50839B1 (en) * 1980-02-26 1986-07-23 Wyeth John & Brother Ltd Novel processes for preparing proline derivatives and analogous compounds
EP0042100A1 (de) * 1980-06-13 1981-12-23 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel
US4320057A (en) * 1980-06-23 1982-03-16 American Home Products Corporation Aryl--pyrrolo--thiazepin--diones and aryl--piperidino--thiazepin--diones
US4415496A (en) * 1981-03-23 1983-11-15 Merck & Co., Inc. Bicyclic lactams
ZA833214B (en) * 1982-05-12 1983-12-28 Hoffmann La Roche Bicyclic compounds
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
US4552889A (en) * 1983-06-09 1985-11-12 Eli Lilly And Company 3-Mercaptomethyl-2-oxo-1-pyrrolidine acetic acids and use for hypertension
US4692438A (en) * 1984-08-24 1987-09-08 Hoffmann-La Roche Inc. Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity
US4584294A (en) * 1984-11-07 1986-04-22 Merck & Co., Inc. Fused tricyclic lactams as angiotensin converting enzyme inhibitors and as antihypertensive agents
HUT40660A (en) * 1985-04-30 1987-01-28 Lilly Co Eli Process for production of derivatives of 7-substituated bicyclic pirasilididone
ZA874107B (no) * 1986-06-13 1987-12-09
ZA874106B (en) * 1986-06-13 1987-12-08 Merrell Dow Pharmaceuticals Inc. Novel antihypertensive agent
US4973585A (en) * 1986-06-13 1990-11-27 Merrell Dow Pharmaceuticals Tricyclic lactams active as antihypertensive agents
GB8629875D0 (en) * 1986-12-15 1987-01-28 Hoffmann La Roche Pyridazodiazepine derivatives
US4824832A (en) * 1987-12-30 1989-04-25 Merrell Dow Pharmaceuticals Inc. Sulfhydryl containing tricyclic lactams and their pharmacological methods of use
US5061694A (en) * 1989-10-23 1991-10-29 E. R. Squibb & Sons, Inc. Method for stabilizing or causing regression of atherosclerosis in coronary arteries employing an ace inhibitor
GB8926512D0 (en) * 1989-11-23 1990-01-10 Pfizer Ltd Therapeutic agents
AU7168091A (en) * 1989-12-22 1991-07-24 Schering Corporation Mercaptocycloacyl aminoacid endopeptidase inhibitors
CA2053340C (en) * 1990-10-18 2002-04-02 Timothy P. Burkholder Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
CA2057786C (en) * 1990-12-21 2002-06-18 Gary A. Flynn Amino and nitro containing tricyclic compounds useful as inhibitors or ace
US5208230A (en) * 1990-12-21 1993-05-04 Merrell Dow Pharmaceuticals Amino and nitro containing tricyclic compounds useful as inhibitors of ACE
FR2679564A1 (fr) * 1991-07-23 1993-01-29 Inst Nat Sante Rech Med Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent.
EP0533084A1 (en) * 1991-09-16 1993-03-24 Schering Corporation Pharmaceutical compositions comprising natriuretic peptides or neutral endopeptidase inhibitors for treating and preventing myointimal proliferation
RU2124503C1 (ru) * 1992-05-18 1999-01-10 И.Р.Сквибб энд Санз, Инк. Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция
US5238932A (en) * 1992-05-20 1993-08-24 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase

Also Published As

Publication number Publication date
US5484783A (en) 1996-01-16
ES2173180T3 (es) 2002-10-16
CA2184693A1 (en) 1995-09-28
HU9602603D0 (en) 1996-11-28
NZ282949A (en) 1997-07-27
WO1995025548A2 (en) 1995-09-28
PT751775E (pt) 2002-10-31
CN1144483A (zh) 1997-03-05
EP0751775A1 (en) 1997-01-08
FI963785A (fi) 1996-09-23
FI963785A0 (fi) 1996-09-23
FI118414B (fi) 2007-11-15
EP0751775B1 (en) 2002-05-15
IL113074A0 (en) 1995-06-29
HUT74886A (en) 1997-02-28
AU2091495A (en) 1995-10-09
ZA952285B (en) 1996-01-09
DE69526731D1 (en) 2002-06-20
DK0751775T3 (da) 2002-08-26
JPH09510220A (ja) 1997-10-14
NO313176B1 (no) 2002-08-26
CA2184693C (en) 2001-01-02
HU226643B1 (en) 2009-05-28
DE69526731T2 (de) 2003-02-06
AU705029B2 (en) 1999-05-13
TW323954B (en) 1998-01-01
IL113074A (en) 2000-07-26
WO1995025548A3 (en) 1995-11-09
NO963989L (no) 1996-11-22
KR970701550A (ko) 1997-04-12
ATE217527T1 (de) 2002-06-15

Similar Documents

Publication Publication Date Title
PL323825A1 (en) Peptidyloheterocycli compounds useful in treating diorders associated with thrombosin
AU4588489A (en) Hypocholesterolemic and antiatherosclerotic uses of bis(3,5-di-tertiary-4-hydroxyphenylthio)methane
BR9504072A (pt) Composiçao farmacêutica métodos para o tratamento de hipercolesterolemia de aterosclerose e kit
NO963989L (no) Hypokolesterolemiske-, antiatherosklerotiske- og hypotriglyceridemiske mercaptoacetylamidderivater
NO963987D0 (no) Hypokolesterolemiske-, antiatherosklerotiske-, og hypotriglyceridemiske aminoacetylmercaptoderivater
CA2184692A1 (en) Hypocholesterolemic, Antiatherosclerotic and Hypotriglyceridemic Mercaptoacetylamide Disulfide Derivatives
DE69409961T2 (de) Triarylethylenderivate zur therapeutischen verwendung
BA95039A (bs) Set za prevenciju i terapiju bolne menstruacije

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees