ZA949785B - Combination preparations comprising a quinoxaline and a nucleoside - Google Patents

Combination preparations comprising a quinoxaline and a nucleoside

Info

Publication number
ZA949785B
ZA949785B ZA949785A ZA949785A ZA949785B ZA 949785 B ZA949785 B ZA 949785B ZA 949785 A ZA949785 A ZA 949785A ZA 949785 A ZA949785 A ZA 949785A ZA 949785 B ZA949785 B ZA 949785B
Authority
ZA
South Africa
Prior art keywords
nucleoside
quinoxaline
combination preparations
formulae
substituents
Prior art date
Application number
ZA949785A
Other languages
English (en)
Inventor
Christoph Meichsner
Guenther Riess
Joerg-Peter Kleim
Manfred Roesner
Arno Paessens
Martin Blunck
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA949785B publication Critical patent/ZA949785B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
ZA949785A 1993-12-09 1994-12-08 Combination preparations comprising a quinoxaline and a nucleoside ZA949785B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4342024A DE4342024A1 (de) 1993-12-09 1993-12-09 Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid

Publications (1)

Publication Number Publication Date
ZA949785B true ZA949785B (en) 1995-07-12

Family

ID=6504591

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA949785A ZA949785B (en) 1993-12-09 1994-12-08 Combination preparations comprising a quinoxaline and a nucleoside

Country Status (12)

Country Link
EP (1) EP0657166B1 (xx)
JP (1) JPH07196511A (xx)
KR (1) KR950016754A (xx)
CN (1) CN1108935A (xx)
AT (1) ATE236642T1 (xx)
AU (1) AU697486B2 (xx)
CA (1) CA2137605A1 (xx)
DE (2) DE4342024A1 (xx)
HU (1) HU221498B (xx)
IL (1) IL111909A0 (xx)
NZ (1) NZ270088A (xx)
ZA (1) ZA949785B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4437406A1 (de) * 1994-10-19 1996-04-25 Hoechst Ag Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19703131A1 (de) * 1997-01-29 1998-07-30 Bayer Ag Verwendung von Chinoxalin in Dreier-Kombination mit Protease-Inhibitoren und Reverse Transkriptaseinhibitoren als Arzneimittel zur Behandlung von AIDS und/oder HIV-Infektionen
DE19727117A1 (de) * 1997-06-26 1999-01-07 Boehringer Ingelheim Pharma Phenylalkylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
WO1999025327A2 (en) * 1997-11-14 1999-05-27 Warner-Lambert Company Small molecule intervention in hiv-1 replication
CA2334332A1 (en) * 1998-06-26 2000-01-06 Robert Joseph Mchugh Substituted quinoxalin-2(1h)-ones useful as hiv reverse transcriptase inhibitors
GB9821000D0 (en) * 1998-09-28 1998-11-18 Glaxo Group Ltd Antiviral combinations
GB9911887D0 (en) * 1999-05-21 1999-07-21 Glaxo Group Ltd Methods and medicaments for post exposure prophylaxis of an hiv infection
WO2005018531A2 (fr) * 2003-08-26 2005-03-03 'chemical Diversity Research Institute', Ltd. Compositions pharmaceutiques, composes azo-heterocycliques et procedes de fabrication et d'utilisation correspondants
AU2004278372B2 (en) * 2003-09-30 2010-02-18 Janssen Pharmaceutica N.V. Quinoxaline compounds
US7351709B2 (en) 2004-06-09 2008-04-01 Wyeth Estrogen receptor ligands
ES2955206T3 (es) 2013-07-15 2023-11-29 Helmholtz Zentrum Muenchen Deutsches Forschungszentrum Gesundheit & Umwelt Gmbh Derivados de espiroquinoxalina como inhibidores de la muerte celular regulada no apoptótica
WO2016075137A1 (en) 2014-11-10 2016-05-19 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Spiropyrazine derivatives as inhibitors of non-apoptotic regulated cell-death
DE102017005089A1 (de) 2016-05-30 2017-11-30 Bayer Pharma Aktiengesellschaft Substitulerte 3,4-Dihydrochinoxalin-2(1H)-one
DE102017005091A1 (de) 2016-05-30 2017-11-30 Bayer Pharma Aktiengesellschaft Substituierte 3,4-Dihydropyrido[2,3-b]pyrazin-2(1H)-one

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59209965D1 (de) * 1991-04-15 2002-10-17 Aventis Pharma Gmbh Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
HU221498B (en) 2002-10-28
HUT70037A (en) 1995-09-28
CA2137605A1 (en) 1995-06-10
EP0657166A1 (de) 1995-06-14
EP0657166B1 (de) 2003-04-09
IL111909A0 (en) 1995-03-15
CN1108935A (zh) 1995-09-27
HU9403518D0 (en) 1995-02-28
DE59410271D1 (de) 2003-05-15
NZ270088A (en) 1998-04-27
AU697486B2 (en) 1998-10-08
DE4342024A1 (de) 1995-06-14
JPH07196511A (ja) 1995-08-01
KR950016754A (ko) 1995-07-20
AU8042194A (en) 1995-06-15
ATE236642T1 (de) 2003-04-15

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