ZA946008B - Novel tripeptides useful in immune and cns therapy - Google Patents
Novel tripeptides useful in immune and cns therapyInfo
- Publication number
- ZA946008B ZA946008B ZA946008A ZA946008A ZA946008B ZA 946008 B ZA946008 B ZA 946008B ZA 946008 A ZA946008 A ZA 946008A ZA 946008 A ZA946008 A ZA 946008A ZA 946008 B ZA946008 B ZA 946008B
- Authority
- ZA
- South Africa
- Prior art keywords
- immune
- cns therapy
- novel tripeptides
- useful
- tripeptides useful
- Prior art date
Links
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C07K5/06095—Arg-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/112,413 US5639729A (en) | 1993-08-26 | 1993-08-26 | Tripeptides useful in immune and CNS therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA946008B true ZA946008B (en) | 1995-03-29 |
Family
ID=22343770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA946008A ZA946008B (en) | 1993-08-26 | 1994-08-10 | Novel tripeptides useful in immune and cns therapy |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5639729A (xx) |
| EP (1) | EP0723454B1 (xx) |
| JP (1) | JPH09502175A (xx) |
| KR (1) | KR960703612A (xx) |
| CN (1) | CN1133563A (xx) |
| AT (1) | ATE207757T1 (xx) |
| BR (1) | BR9407357A (xx) |
| CA (1) | CA2169072A1 (xx) |
| CZ (1) | CZ55496A3 (xx) |
| DE (1) | DE69428909D1 (xx) |
| FI (1) | FI960839A0 (xx) |
| HU (1) | HUT73777A (xx) |
| IL (1) | IL110585A0 (xx) |
| NO (1) | NO960710D0 (xx) |
| PL (1) | PL313257A1 (xx) |
| WO (1) | WO1995005841A1 (xx) |
| ZA (1) | ZA946008B (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4727770B2 (ja) * | 1997-09-26 | 2011-07-20 | カルピス株式会社 | 尿中カテコールアミン低下、尿中ノルアドレナリン低下、尿中ドーパミン低下及びＦｉｓｃｈｅｒ比低下の少なくとも１つの軽減剤 |
| EP1401808B1 (en) | 2001-05-24 | 2009-07-08 | Neuren Pharmaceuticals Limited | Gpe analogs and peptidomimetics |
| US7714020B2 (en) * | 2001-05-24 | 2010-05-11 | Neuren Pharmaceuticals Limited | Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate |
| US20070004641A1 (en) * | 2001-05-24 | 2007-01-04 | Neuren Pharmaceuticals Limited | Cognitive enhancement and cognitive therapy using glycyl-L-2-methylprolyl-L-glutamate |
| US7605177B2 (en) * | 2001-05-24 | 2009-10-20 | Neuren Pharmaceuticals Limited | Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration |
| SG187271A1 (en) * | 2011-07-07 | 2013-02-28 | Agency Science Tech & Res | Anti-amyloidogenic, alpha-helix breaking ultra-small peptide therapeutic |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4190646A (en) * | 1975-11-11 | 1980-02-26 | Sloan-Kettering Institute For Cancer Research | Polypeptide compositions and methods |
| US4505853A (en) * | 1983-11-18 | 1985-03-19 | Ortho Pharmaceutical Corporation | Enzyme-resistant immunomodulatory peptides |
| US4629723A (en) * | 1984-06-27 | 1986-12-16 | Ortho Pharmaceutical Corporation | Potent thymopentin analogs |
| US5028592A (en) * | 1986-08-08 | 1991-07-02 | Lipton James M | Antipyretic and anti-inflammatory peptides |
| IT1216908B (it) * | 1987-03-19 | 1990-03-14 | Eniricerche Spa | Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche. |
| IT1222437B (it) * | 1987-08-04 | 1990-09-05 | Ellem Ind Farmaceutica | Tripeptidi utili come immunostimolanti e nella prevenzione delle metastasi e relativo procedimento di preparazione |
| NZ229004A (en) * | 1988-05-19 | 1993-09-27 | Immunobiology Res Inst Inc | Tetrapeptides having t cell helper acitivity |
| HU201095B (en) * | 1988-06-14 | 1990-09-28 | Richter Gedeon Vegyeszet | New peptides inhibiting the activity of the immune system and pharmaceutical compositions comprising same, as well as process for producing these peptides and compositions |
| WO1990003180A1 (en) * | 1988-09-30 | 1990-04-05 | Immunobiology Research Institute, Inc. | Peptides having t cell suppressor activity |
| DD296084A5 (de) * | 1989-07-27 | 1991-11-21 | Adw | Verfahren zur herstellung von humanen spleninderivaten |
-
1993
- 1993-08-26 US US08/112,413 patent/US5639729A/en not_active Expired - Fee Related
-
1994
- 1994-08-08 IL IL11058594A patent/IL110585A0/xx unknown
- 1994-08-10 ZA ZA946008A patent/ZA946008B/xx unknown
- 1994-08-17 AT AT94929727T patent/ATE207757T1/de not_active IP Right Cessation
- 1994-08-17 JP JP7507652A patent/JPH09502175A/ja not_active Ceased
- 1994-08-17 KR KR1019960700948A patent/KR960703612A/ko not_active Application Discontinuation
- 1994-08-17 BR BR9407357A patent/BR9407357A/pt not_active Application Discontinuation
- 1994-08-17 PL PL94313257A patent/PL313257A1/xx unknown
- 1994-08-17 DE DE69428909T patent/DE69428909D1/de not_active Expired - Lifetime
- 1994-08-17 EP EP94929727A patent/EP0723454B1/en not_active Expired - Lifetime
- 1994-08-17 CA CA002169072A patent/CA2169072A1/en not_active Abandoned
- 1994-08-17 CN CN94193916A patent/CN1133563A/zh active Pending
- 1994-08-17 HU HU9600432A patent/HUT73777A/hu unknown
- 1994-08-17 WO PCT/US1994/009290 patent/WO1995005841A1/en active IP Right Grant
- 1994-08-17 CZ CZ96554A patent/CZ55496A3/cs unknown
-
1996
- 1996-02-22 NO NO960710A patent/NO960710D0/no unknown
- 1996-02-23 FI FI960839A patent/FI960839A0/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL313257A1 (en) | 1996-06-24 |
| JPH09502175A (ja) | 1997-03-04 |
| IL110585A0 (en) | 1994-11-11 |
| FI960839A (fi) | 1996-02-23 |
| ATE207757T1 (de) | 2001-11-15 |
| NO960710L (no) | 1996-02-22 |
| NO960710D0 (no) | 1996-02-22 |
| CZ55496A3 (en) | 1996-08-14 |
| DE69428909D1 (de) | 2001-12-06 |
| US5639729A (en) | 1997-06-17 |
| KR960703612A (ko) | 1996-08-31 |
| AU682898B2 (en) | 1997-10-23 |
| EP0723454A1 (en) | 1996-07-31 |
| HUT73777A (en) | 1996-09-30 |
| CN1133563A (zh) | 1996-10-16 |
| EP0723454A4 (en) | 1998-07-29 |
| EP0723454B1 (en) | 2001-10-31 |
| BR9407357A (pt) | 1996-10-29 |
| HU9600432D0 (en) | 1996-04-29 |
| FI960839A0 (fi) | 1996-02-23 |
| WO1995005841A1 (en) | 1995-03-02 |
| CA2169072A1 (en) | 1995-03-02 |
| AU7868194A (en) | 1995-03-21 |
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