ZA945782B - Skin patches and methods for providing testosterone and optionally estrogen replacement therapy to women - Google Patents
Skin patches and methods for providing testosterone and optionally estrogen replacement therapy to womenInfo
- Publication number
- ZA945782B ZA945782B ZA945782A ZA945782A ZA945782B ZA 945782 B ZA945782 B ZA 945782B ZA 945782 A ZA945782 A ZA 945782A ZA 945782 A ZA945782 A ZA 945782A ZA 945782 B ZA945782 B ZA 945782B
- Authority
- ZA
- South Africa
- Prior art keywords
- women
- methods
- replacement therapy
- skin patches
- estrogen replacement
- Prior art date
Links
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 229960003604 testosterone Drugs 0.000 title abstract 2
- 239000007933 dermal patch Substances 0.000 title 1
- 238000009164 estrogen replacement therapy Methods 0.000 title 1
- 238000009165 androgen replacement therapy Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Nutrition Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08099923 US5460820B1 (en) | 1993-08-03 | 1993-08-03 | Method for providing testosterone and optionally estrogen replacement therapy to women |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA945782B true ZA945782B (en) | 1995-03-10 |
Family
ID=22277259
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA945782A ZA945782B (en) | 1993-08-03 | 1994-08-03 | Skin patches and methods for providing testosterone and optionally estrogen replacement therapy to women |
Country Status (17)
Country | Link |
---|---|
US (1) | US5460820B1 (es) |
EP (2) | EP1604651A1 (es) |
JP (4) | JPH09500653A (es) |
KR (1) | KR0180030B1 (es) |
CN (2) | CN1142753C (es) |
AT (1) | ATE304845T1 (es) |
AU (1) | AU690578B2 (es) |
CA (1) | CA2168879C (es) |
DE (2) | DE122007000006I1 (es) |
DK (1) | DK0712303T4 (es) |
ES (1) | ES2245777T5 (es) |
LU (1) | LU91309I2 (es) |
NL (1) | NL300259I2 (es) |
NO (1) | NO316844B1 (es) |
TW (1) | TW492881B (es) |
WO (1) | WO1995003764A1 (es) |
ZA (1) | ZA945782B (es) |
Families Citing this family (73)
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US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
DE19517145C2 (de) * | 1995-05-10 | 2000-02-24 | Hexal Pharmaforschung Gmbh | Transdermales therapeutisches System (TTS) zur Verabreichung von Testosteron |
AUPN814496A0 (en) | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
AU2746397A (en) * | 1996-04-30 | 1997-11-19 | Theratech, Inc. | Transdermal administration of steroid hormones using diethanolamides of c12-c18 fatty acids as permeation enhancers |
US6228852B1 (en) * | 1996-07-12 | 2001-05-08 | Carolyn V. Shaak | Transdermal application of naturally occurring steroid hormones |
US5783208A (en) * | 1996-07-19 | 1998-07-21 | Theratech, Inc. | Transdermal drug delivery matrix for coadministering estradiol and another steroid |
DE19646050A1 (de) * | 1996-11-08 | 1998-05-14 | Labtec Gmbh | Transdermales System mit einem speziellen Süßstoff zur Erhöhung der transdermalen Bioverfügbarkeit |
US5951999A (en) | 1997-02-21 | 1999-09-14 | Adhesives Research, Inc. | Transdermal pressure sensitive adhesive drug delivery system |
US6056972A (en) * | 1997-02-26 | 2000-05-02 | Dimera, Llc | Method for reducing coronary artery reactivity |
HUP0001748A3 (en) * | 1997-02-28 | 2001-03-28 | Minnesota Mining And Mfg Co Sa | Transdermal device for the delivery of testosterone |
US8765177B2 (en) * | 1997-09-12 | 2014-07-01 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
US6248358B1 (en) | 1998-08-25 | 2001-06-19 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets and methods of making and using the same |
US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
US6624200B2 (en) | 1998-08-25 | 2003-09-23 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
GB9720470D0 (en) * | 1997-09-25 | 1997-11-26 | Ethical Pharmaceuticals South | Inhibition of crystallization in transdermal devices |
US5891868A (en) * | 1997-11-21 | 1999-04-06 | Kaiser Foundation Health Plan, Inc. | Methods for treating postmenopausal women using ultra-low doses of estrogen |
US6692763B1 (en) | 1998-11-19 | 2004-02-17 | The Regents Of The University Of California | Methods for treating postmenopausal women using ultra-low doses of estrogen |
KR100464601B1 (ko) * | 1998-10-23 | 2004-12-31 | 이데아 악티엔게젤샤프트 | 페이로드를 증가시키고, 분리/결합율을 제어하기 위한 거대 분자 결합체 및 복합응집체의 생장, 시험 및 사용방법 |
SI1031347T1 (en) | 1999-01-27 | 2002-10-31 | Idea Ag | Transnasal transport/immunisation with highly adaptable carriers |
EP1031346B1 (en) | 1999-01-27 | 2002-05-02 | Idea Ag | Noninvasive vaccination through the skin |
PE20010404A1 (es) * | 1999-06-11 | 2001-04-09 | Watson Pharmaceuticals Inc | Combinacion de esteroides androgenicos no orales y compuestos estrogenicos y su uso en mujeres |
AU2004222794B2 (en) * | 1999-06-11 | 2007-03-08 | Watson Pharmaceuticals, Inc. | Non-oral androgenic steroids for women |
WO2001001962A1 (en) * | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
AU1585601A (en) * | 1999-11-04 | 2001-05-14 | Xel Herbaceuticals | Transdermal administration of huperzine |
US6896898B1 (en) | 1999-11-19 | 2005-05-24 | Xel Herbaceuticals, Inc. | Transdermal delivery system for alkaloids of aconitum species |
US20050042271A1 (en) * | 1999-11-19 | 2005-02-24 | Xel Herbaceuticals, Inc . | Transdermal delivery system for alkaloids of aconitum species |
US6673363B2 (en) | 1999-12-16 | 2004-01-06 | Dermatrends, Inc. | Transdermal and topical administration of local anesthetic agents using basic enhancers |
US6582724B2 (en) | 1999-12-16 | 2003-06-24 | Dermatrends, Inc. | Dual enhancer composition for topical and transdermal drug delivery |
US6586000B2 (en) | 1999-12-16 | 2003-07-01 | Dermatrends, Inc. | Hydroxide-releasing agents as skin permeation enhancers |
US20030104041A1 (en) * | 1999-12-16 | 2003-06-05 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
US6562369B2 (en) * | 1999-12-16 | 2003-05-13 | Dermatrends, Inc. | Transdermal administration of androgenic drugs hydroxide-releasing agents as permeation enhancers |
KR100403051B1 (ko) * | 2000-07-25 | 2003-10-23 | 일양약품주식회사 | 음낭 외 피부에 적용가능한 남성호르몬 경피흡수 패취제 |
US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
US20020107230A1 (en) * | 2000-12-22 | 2002-08-08 | Waldon R. Forrest | Methods and formulations for the treatment of female sexual dysfunction |
US7921999B1 (en) * | 2001-12-20 | 2011-04-12 | Watson Laboratories, Inc. | Peelable pouch for transdermal patch and method for packaging |
US20030191096A1 (en) * | 2002-04-03 | 2003-10-09 | Leonard Thomas W. | Method of hormonal therapy |
US20040105881A1 (en) * | 2002-10-11 | 2004-06-03 | Gregor Cevc | Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin |
IL152573A (en) * | 2002-10-31 | 2009-11-18 | Transpharma Medical Ltd | A system for the transmission through the skin of a medical preparation against vomiting and nausea |
IL152575A (en) * | 2002-10-31 | 2008-12-29 | Transpharma Medical Ltd | A skin-to-skin transmission system of water-insoluble drugs |
CA2433101A1 (en) * | 2003-06-23 | 2004-12-23 | Igor Gonda | Method of treatment of a female suffering from androgen insufficiency |
US20070231373A1 (en) * | 2004-04-28 | 2007-10-04 | Hunter-Fleming Limited | Transdermal Steriod for Formulation |
US20070196452A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Flux-enabling compositions and methods for dermal delivery of drugs |
US8741333B2 (en) * | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for treating dermatitis or psoriasis |
US20070196453A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Two or more non-volatile solvent-containing compositions and methods for dermal delivery of drugs |
US8907153B2 (en) * | 2004-06-07 | 2014-12-09 | Nuvo Research Inc. | Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same |
US8741332B2 (en) * | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for dermally treating neuropathic pain |
WO2006050926A2 (en) * | 2004-11-12 | 2006-05-18 | Idea Ag | Extended surface aggregates in the treatment of skin conditions |
US7833979B2 (en) * | 2005-04-22 | 2010-11-16 | Amgen Inc. | Toxin peptide therapeutic agents |
US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
US10137135B2 (en) * | 2005-08-15 | 2018-11-27 | Allergan Sales, Llc | Formulations and methods for providing progestin-only contraception while minimizing adverse side effects associated therewith |
ZA200803087B (en) | 2005-10-12 | 2009-11-25 | Unimed Pharmaceuticals Llc | Improved testosterone gel and method of use |
US20080015170A1 (en) * | 2005-12-01 | 2008-01-17 | The Procter & Gamble Company | Method of treating menopausal women transdermally with testosterone |
EP1839705A1 (en) | 2006-03-27 | 2007-10-03 | Universidad de Alcala | Transcutaneous laser therapy patch |
US20070280972A1 (en) * | 2006-04-25 | 2007-12-06 | Zars, Inc. | Adhesive solid gel-forming formulations for dermal drug delivery |
PE20081140A1 (es) | 2006-10-25 | 2008-09-22 | Amgen Inc | Agentes terapeuticos a base de peptidos derivados de toxinas |
CA2687141C (en) | 2007-05-22 | 2014-04-01 | Amgen Inc. | Compositions and methods for producing bioactive fusion proteins |
US20090285893A1 (en) * | 2008-05-19 | 2009-11-19 | The Procter & Gamble Company | Treatment of heart failure in women |
US20100061976A1 (en) * | 2008-07-24 | 2010-03-11 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method for treating or preventing osteoporosis by reducing follicle stimulating hormone to cyclic physiological levels in a mammalian subject |
US20100022487A1 (en) * | 2008-07-24 | 2010-01-28 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method, device, and kit for maintaining physiological levels of steroid hormone in a subject |
US20100022494A1 (en) * | 2008-07-24 | 2010-01-28 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method, device, and kit for maintaining physiological levels of steroid hormone in a subject |
US20100022497A1 (en) * | 2008-07-24 | 2010-01-28 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method for treating or preventing a cardiovascular disease or condition utilizing estrogen receptor modulators based on APOE allelic profile of a mammalian subject |
US9320742B2 (en) * | 2009-12-01 | 2016-04-26 | Noven Pharmaceuticals, Inc. | Transdermal testosterone device and delivery |
UY33959A (es) | 2011-03-16 | 2012-09-28 | Amgen Inc | INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.3 Y NaV1.7 |
CN102772417B (zh) * | 2012-07-24 | 2014-01-29 | 上海现代药物制剂工程研究中心有限公司 | 包载睾酮的自黏性弹性体基质的周效经皮贴剂及制法 |
US9006462B2 (en) | 2013-02-28 | 2015-04-14 | Dermira, Inc. | Glycopyrrolate salts |
JP6114841B2 (ja) | 2013-02-28 | 2017-04-12 | ダーミラ, インク.Dermira, Inc. | グリコピロレート塩 |
US8558008B2 (en) | 2013-02-28 | 2013-10-15 | Dermira, Inc. | Crystalline glycopyrrolate tosylate |
EP2970408B1 (en) | 2013-03-12 | 2018-01-10 | Amgen Inc. | Potent and selective inhibitors of nav1.7 |
US9452174B2 (en) * | 2014-08-20 | 2016-09-27 | Professional Compounding Centers Of America | Oral transmucosal pharmaceutical compositions including testosterone and a C-SERM |
PT109445B (pt) | 2016-06-08 | 2018-11-06 | Hovione Farm Sa | Co-cristais farmacêuticos cristalinos de brometo de glicopirrónio com lactose |
US11318190B2 (en) | 2017-05-05 | 2022-05-03 | United States Government As Represented By The Department Of Veterans Affairs | Methods and compositions for treating liver disease |
WO2020010205A1 (en) * | 2018-07-05 | 2020-01-09 | Celista Pharmaceuticals Llc | Testosterone and estradiol transdermal spray |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5023084A (en) * | 1986-12-29 | 1991-06-11 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
US4994267A (en) * | 1988-03-04 | 1991-02-19 | Noven Pharmaceuticals, Inc. | Transdermal acrylic multipolymer drug delivery system |
AU644815B2 (en) † | 1989-09-08 | 1993-12-23 | Ortho-Mcneil Pharmaceutical, Inc. | Solid matrix system for transdermal drug delivery |
US5122383A (en) * | 1991-05-17 | 1992-06-16 | Theratech, Inc. | Sorbitan esters as skin permeation enhancers |
US5152997A (en) * | 1990-12-11 | 1992-10-06 | Theratech, Inc. | Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels |
US5164190A (en) * | 1990-12-11 | 1992-11-17 | Theratech, Inc. | Subsaturated transdermal drug delivery device exhibiting enhanced drug flux |
US5211952A (en) | 1991-04-12 | 1993-05-18 | University Of Southern California | Contraceptive methods and formulations for use therein |
US5340586A (en) * | 1991-04-12 | 1994-08-23 | University Of Southern California | Methods and formulations for use in treating oophorectomized women |
DE4210165A1 (de) † | 1991-07-30 | 1993-02-04 | Schering Ag | Transdermale therapeutische systeme |
-
1993
- 1993-08-03 US US08099923 patent/US5460820B1/en not_active Expired - Lifetime
-
1994
- 1994-07-27 EP EP05010937A patent/EP1604651A1/en not_active Withdrawn
- 1994-07-27 DE DE1994634491 patent/DE122007000006I1/de active Pending
- 1994-07-27 KR KR1019960700568A patent/KR0180030B1/ko not_active IP Right Cessation
- 1994-07-27 WO PCT/US1994/008637 patent/WO1995003764A1/en active IP Right Grant
- 1994-07-27 EP EP94925151A patent/EP0712303B2/en not_active Expired - Lifetime
- 1994-07-27 DE DE69434491T patent/DE69434491T3/de not_active Expired - Lifetime
- 1994-07-27 CA CA002168879A patent/CA2168879C/en not_active Expired - Lifetime
- 1994-07-27 JP JP7506022A patent/JPH09500653A/ja active Pending
- 1994-07-27 DK DK94925151T patent/DK0712303T4/da active
- 1994-07-27 ES ES94925151T patent/ES2245777T5/es not_active Expired - Lifetime
- 1994-07-27 CN CNB941935469A patent/CN1142753C/zh not_active Expired - Fee Related
- 1994-07-27 CN CNA200410001875XA patent/CN1550233A/zh active Pending
- 1994-07-27 AT AT94925151T patent/ATE304845T1/de active
- 1994-07-27 AU AU75178/94A patent/AU690578B2/en not_active Ceased
- 1994-08-03 ZA ZA945782A patent/ZA945782B/xx unknown
- 1994-08-16 TW TW083107504A patent/TW492881B/zh not_active IP Right Cessation
-
1996
- 1996-02-02 NO NO19960445A patent/NO316844B1/no not_active IP Right Cessation
-
2001
- 2001-08-13 JP JP2001245748A patent/JP2002121136A/ja not_active Withdrawn
-
2005
- 2005-06-14 JP JP2005174407A patent/JP2005263814A/ja not_active Withdrawn
-
2007
- 2007-01-25 NL NL300259C patent/NL300259I2/nl unknown
- 2007-01-25 LU LU91309C patent/LU91309I2/fr unknown
-
2009
- 2009-05-25 JP JP2009125890A patent/JP2009185074A/ja active Pending
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