ZA94398B - Combination of a soluble complement receptor-1(scr1) and an amidinophenyl or amidino napthyl-ester for treating inflammation - Google Patents

Combination of a soluble complement receptor-1(scr1) and an amidinophenyl or amidino napthyl-ester for treating inflammation

Info

Publication number
ZA94398B
ZA94398B ZA94398A ZA94398A ZA94398B ZA 94398 B ZA94398 B ZA 94398B ZA 94398 A ZA94398 A ZA 94398A ZA 94398 A ZA94398 A ZA 94398A ZA 94398 B ZA94398 B ZA 94398B
Authority
ZA
South Africa
Prior art keywords
amidinophenyl
scr1
napthyl
amidino
ester
Prior art date
Application number
ZA94398A
Other languages
English (en)
Inventor
Danutha Ewa Irena Mossakowska
Richard Anthony Godwin Smith
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of ZA94398B publication Critical patent/ZA94398B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA94398A 1993-01-22 1994-01-20 Combination of a soluble complement receptor-1(scr1) and an amidinophenyl or amidino napthyl-ester for treating inflammation ZA94398B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939301289A GB9301289D0 (en) 1993-01-22 1993-01-22 Novel composition

Publications (1)

Publication Number Publication Date
ZA94398B true ZA94398B (en) 1994-11-15

Family

ID=10729169

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA94398A ZA94398B (en) 1993-01-22 1994-01-20 Combination of a soluble complement receptor-1(scr1) and an amidinophenyl or amidino napthyl-ester for treating inflammation

Country Status (10)

Country Link
EP (1) EP0680332A1 (enExample)
JP (1) JPH08505867A (enExample)
CN (1) CN1118141A (enExample)
AU (1) AU5863694A (enExample)
CA (1) CA2153797A1 (enExample)
GB (1) GB9301289D0 (enExample)
NZ (1) NZ259737A (enExample)
TW (1) TW241203B (enExample)
WO (1) WO1994016719A1 (enExample)
ZA (1) ZA94398B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69431194T2 (de) * 1993-10-21 2002-12-12 G.D. Searle & Co., Chicago Amidino-derivate nützlich als no synthase-hemmer
GB9604518D0 (en) * 1996-03-02 1996-05-01 Smithkline Beecham Plc Novel compounds
US8088386B2 (en) * 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
JP4897690B2 (ja) * 2004-10-12 2012-03-14 ジェネンテック, インコーポレイテッド 補体関連障害の予防および処置のためのCRIgポリペプチド
GB201800620D0 (en) 2018-01-15 2018-02-28 Univ Manchester C3b Binding Polypeptide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions
GB2095239B (en) * 1981-02-27 1985-03-06 Torii & Co Ltd Novel amidine compounds
JPS57179147A (en) * 1981-04-28 1982-11-04 Torii Yakuhin Kk Amidine derivative
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
EP0560929A1 (en) * 1990-12-06 1993-09-22 T Cell Sciences, Inc. Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity

Also Published As

Publication number Publication date
JPH08505867A (ja) 1996-06-25
EP0680332A1 (en) 1995-11-08
NZ259737A (en) 1997-04-24
WO1994016719A1 (en) 1994-08-04
CA2153797A1 (en) 1994-08-04
AU5863694A (en) 1994-08-15
GB9301289D0 (en) 1993-03-17
CN1118141A (zh) 1996-03-06
TW241203B (enExample) 1995-02-21

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