AU5863694A - Combination of a soluble complement receptor -1(scr1) and an amidinophenyl or amidino naphthyl-ester for treating inflammation - Google Patents

Combination of a soluble complement receptor -1(scr1) and an amidinophenyl or amidino naphthyl-ester for treating inflammation

Info

Publication number
AU5863694A
AU5863694A AU58636/94A AU5863694A AU5863694A AU 5863694 A AU5863694 A AU 5863694A AU 58636/94 A AU58636/94 A AU 58636/94A AU 5863694 A AU5863694 A AU 5863694A AU 5863694 A AU5863694 A AU 5863694A
Authority
AU
Australia
Prior art keywords
apan
brl55730
amidinophenyl
ester
complement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU58636/94A
Other languages
English (en)
Inventor
Danuta Ewa Irena Mossakowska
Richard Anthony Godwin Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of AU5863694A publication Critical patent/AU5863694A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU58636/94A 1993-01-22 1994-01-21 Combination of a soluble complement receptor -1(scr1) and an amidinophenyl or amidino naphthyl-ester for treating inflammation Abandoned AU5863694A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939301289A GB9301289D0 (en) 1993-01-22 1993-01-22 Novel composition
GB9301289 1993-01-22
PCT/GB1994/000122 WO1994016719A1 (en) 1993-01-22 1994-01-21 Combination of a soluble complement receptor -1(scr1) and an amidinophenyl or amidino naphthyl-ester for treating inflammation

Publications (1)

Publication Number Publication Date
AU5863694A true AU5863694A (en) 1994-08-15

Family

ID=10729169

Family Applications (1)

Application Number Title Priority Date Filing Date
AU58636/94A Abandoned AU5863694A (en) 1993-01-22 1994-01-21 Combination of a soluble complement receptor -1(scr1) and an amidinophenyl or amidino naphthyl-ester for treating inflammation

Country Status (10)

Country Link
EP (1) EP0680332A1 (enExample)
JP (1) JPH08505867A (enExample)
CN (1) CN1118141A (enExample)
AU (1) AU5863694A (enExample)
CA (1) CA2153797A1 (enExample)
GB (1) GB9301289D0 (enExample)
NZ (1) NZ259737A (enExample)
TW (1) TW241203B (enExample)
WO (1) WO1994016719A1 (enExample)
ZA (1) ZA94398B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09504524A (ja) * 1993-10-21 1997-05-06 ジー．ディー．サール アンド カンパニー 酸化窒素シンターゼ阻害剤として有用なアミジノ誘導体
GB9604518D0 (en) * 1996-03-02 1996-05-01 Smithkline Beecham Plc Novel compounds
US8088386B2 (en) * 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
JP4897690B2 (ja) * 2004-10-12 2012-03-14 ジェネンテック， インコーポレイテッド 補体関連障害の予防および処置のためのＣＲＩｇポリペプチド
GB201800620D0 (en) 2018-01-15 2018-02-28 Univ Manchester C3b Binding Polypeptide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions
FR2500825B1 (fr) * 1981-02-27 1985-08-23 Torii & Co Ltd Nouveau carboxylate de 4-amidino-phenyle substitue, son procede de preparation et agent anti-complement en comprenant
JPS57179147A (en) * 1981-04-28 1982-11-04 Torii Yakuhin Kk Amidine derivative
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
JPH06503344A (ja) * 1990-12-06 1994-04-14 ティーセル　サイエンシズ，インコーポレーテッド 可溶性の補体受容体と、補体を抑制しかつ／または免疫活性を抑制する化合物との相乗組成物

Also Published As

Publication number Publication date
ZA94398B (en) 1994-11-15
GB9301289D0 (en) 1993-03-17
CN1118141A (zh) 1996-03-06
TW241203B (enExample) 1995-02-21
WO1994016719A1 (en) 1994-08-04
EP0680332A1 (en) 1995-11-08
CA2153797A1 (en) 1994-08-04
NZ259737A (en) 1997-04-24
JPH08505867A (ja) 1996-06-25

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