ZA943514B - The use of dihydrolipoic acid as an ophthalmological agent and to suppress intolerance reactions in the area between implants and living body tissue - Google Patents
The use of dihydrolipoic acid as an ophthalmological agent and to suppress intolerance reactions in the area between implants and living body tissueInfo
- Publication number
- ZA943514B ZA943514B ZA943514A ZA943514A ZA943514B ZA 943514 B ZA943514 B ZA 943514B ZA 943514 A ZA943514 A ZA 943514A ZA 943514 A ZA943514 A ZA 943514A ZA 943514 B ZA943514 B ZA 943514B
- Authority
- ZA
- South Africa
- Prior art keywords
- implants
- suppress
- area
- living body
- body tissue
- Prior art date
Links
- IZFHEQBZOYJLPK-SSDOTTSWSA-N (R)-dihydrolipoic acid Chemical compound OC(=O)CCCC[C@@H](S)CCS IZFHEQBZOYJLPK-SSDOTTSWSA-N 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 239000007943 implant Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19934317173 DE4317173C2 (de) | 1993-05-22 | 1993-05-22 | Verwendung von Dihydroliponsäure als Ophthalmologicum |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA943514B true ZA943514B (en) | 1995-02-02 |
Family
ID=6488744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA943514A ZA943514B (en) | 1993-05-22 | 1994-05-20 | The use of dihydrolipoic acid as an ophthalmological agent and to suppress intolerance reactions in the area between implants and living body tissue |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5691379A (cs) |
| EP (1) | EP0697863A1 (cs) |
| JP (1) | JPH08511246A (cs) |
| AU (1) | AU6566794A (cs) |
| CA (1) | CA2162467A1 (cs) |
| DE (1) | DE4345199C2 (cs) |
| IL (1) | IL109701A0 (cs) |
| PH (1) | PH31652A (cs) |
| TW (1) | TW265264B (cs) |
| WO (1) | WO1994027592A1 (cs) |
| ZA (1) | ZA943514B (cs) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19726251C2 (de) * | 1997-06-20 | 2000-03-02 | Mucos Pharma Gmbh & Co | Verwendung proteolytischer Enzyme zur Behandlung von Uveitis |
| US5965618A (en) * | 1997-11-17 | 1999-10-12 | Perricone; Nicholas V. | Treatment of scar tissue using lipoic acid |
| US20050085498A1 (en) * | 1998-05-28 | 2005-04-21 | Byrd Edward A. | Oral formulation of lipid soluble thiamine, lipoic acid, creatine derivative, and L-arginine alpha-ketoglutarate |
| US6905707B2 (en) * | 1998-05-28 | 2005-06-14 | Medical Research Institute | Controlled release arginine alpha ketoglutarate |
| US20040259895A1 (en) * | 1998-05-28 | 2004-12-23 | Medical Research Institute | Oral formulation of lipid soluble thiamine and lipoic acid |
| US6197340B1 (en) | 1998-05-28 | 2001-03-06 | Medical Research Institute | Controlled release lipoic acid |
| US6191162B1 (en) | 1998-05-28 | 2001-02-20 | Medical Research Institute | Method of reducing serum glucose levels |
| US6162393A (en) * | 1998-08-06 | 2000-12-19 | Ndt, Inc. | Contact lens and ophthalmic solutions |
| US6136339A (en) | 1998-08-21 | 2000-10-24 | Gardiner; Paul T. | Food supplements and methods comprising lipoic acid and creatine |
| US6339102B1 (en) * | 1999-06-09 | 2002-01-15 | The United States Of America As Represented By The Secretary Of The Army | Method and composition for treating and preventing retinal damage |
| US7678836B2 (en) * | 1999-11-04 | 2010-03-16 | Fxs Ventures, Llc | Method for rendering a contact lens wettable |
| US8647612B2 (en) * | 2008-03-05 | 2014-02-11 | Encore Health, Llc | Dithiol compounds, derivatives, and treatment of presbyopia |
| US8697109B2 (en) | 2000-08-16 | 2014-04-15 | Encore Health, Llc | Caged mercaptan and seleno-mercaptan compounds and methods of using them |
| US7914815B2 (en) * | 2000-08-16 | 2011-03-29 | Encore Health, Llc | Method for delivery of pharmaceuticals for treating or preventing presbyopia |
| US7935332B2 (en) | 2000-08-16 | 2011-05-03 | Encore Health, Llc | Presbyopia treatment by lens alteration |
| US20050112113A1 (en) * | 2000-08-16 | 2005-05-26 | Till Jonathan S. | Presbyopia treatment by lens alteration |
| US8557868B2 (en) | 2000-11-04 | 2013-10-15 | Fxs Ventures, Llc | Ophthalmic and contact lens solutions using low molecular weight amines |
| EP1331902B1 (en) * | 2000-11-08 | 2008-08-20 | FXS Ventures, LLC | Improved ophthalmic and contact lens solutions containing forms of vitamin b |
| US20060127496A1 (en) * | 2000-11-08 | 2006-06-15 | Bioconcept Laboratories | L-histidine in ophthalmic solutions |
| US20070110782A1 (en) * | 2000-11-08 | 2007-05-17 | Fxs Ventures, Llc | L-histidine in ophthalmic solutions |
| US9492582B2 (en) * | 2000-11-08 | 2016-11-15 | Fxs Ventures, Llc | Ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers |
| US20060148665A1 (en) * | 2000-11-08 | 2006-07-06 | Bioconcept Laboratories | Ophthalmic and contact lens solutions containing forms of vitamin b |
| EP1339418B1 (en) * | 2000-11-08 | 2009-09-23 | FXS Ventures, LLC | Improved ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers |
| US9308264B2 (en) | 2000-11-08 | 2016-04-12 | Fxs Ventures, Llc | Ophthalmic contact lens solutions containing forms of vitamin B |
| US20070098813A1 (en) * | 2000-11-08 | 2007-05-03 | Fxs Ventures, Llc | Ophthalmic and contact lens solutions with a peroxide source and a preservative |
| DE10229995A1 (de) * | 2002-07-03 | 2004-01-15 | Beiersdorf Ag | Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an alpha-Liponsäure |
| US7939501B2 (en) * | 2003-04-15 | 2011-05-10 | Smith Francis X | Ophthalmic and contact lens solutions containing peptides as preservative |
| ITLO20060004A1 (it) * | 2006-08-08 | 2008-02-09 | River Pharma Srl | "lapille" e una nuova invenzione avente per oggetto una nuova combinazione chimica stabile per uso cosmetico e farmaceutico contenente come ingredienti attivi l'acido alfa-lipoico ed il dimetilsulfossido, in grado di migliorare l'assorbimento, la bio |
| WO2008067403A2 (en) * | 2006-11-28 | 2008-06-05 | Encore Health Llc | Presbyopia treatment by lens alteration |
| US8102027B2 (en) * | 2007-08-21 | 2012-01-24 | Broadcom Corporation | IC package sacrificial structures for crack propagation confinement |
| US9044439B2 (en) * | 2008-03-05 | 2015-06-02 | Encore Health, Llc | Low dose lipoic and pharmaceutical compositions and methods |
| WO2009111635A2 (en) | 2008-03-05 | 2009-09-11 | Encore Health, Llc | Dithiol compounds, derivatives, and uses therefor |
| EP2442645B1 (en) * | 2009-06-15 | 2014-08-27 | Encore Health, Llc | Choline esters |
| EP2442647B1 (en) | 2009-06-15 | 2016-03-16 | Encore Health LLC | Dithiol compounds, derivatives, and uses therefor |
| AU2015227307A1 (en) * | 2014-03-03 | 2016-10-13 | Encore Vision, Inc. | Lipoic acid choline ester compositions and methods of use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4002706A1 (de) * | 1989-02-09 | 1990-08-16 | Asta Pharma Ag | Arzneimittel enthaltend als wirkstoff dihydroliponsaeure |
| EP0427246B1 (de) * | 1989-11-09 | 1995-08-09 | ASTA Medica Aktiengesellschaft | Arzneimittel, welche als Wirkstoff Schwefel enthaltende Carbonsäuren enthalten sowie deren Verwendung zur Bekämpfung von Retroviren |
| DE4218572A1 (de) * | 1992-06-05 | 1993-12-09 | Asta Medica Ag | Synergistische Kombination von Arzneimitteln enthaltend als Wirkstoff alpha-Liponsäure, Dihydroliponsäure, deren Metaboliten sowie die oxidierten und reduzierten Enantiomere der alpha-Liponsäure wie die R-alpha-Liponsäure oder S-alpha-Liponsäure sowie Metaboliten der alpha-Liponsäure mit den Vitaminen A, B1-6, B12, C und E |
-
1993
- 1993-05-22 DE DE4345199A patent/DE4345199C2/de not_active Expired - Fee Related
-
1994
- 1994-04-11 WO PCT/EP1994/001110 patent/WO1994027592A1/de not_active Ceased
- 1994-04-11 JP JP7500142A patent/JPH08511246A/ja active Pending
- 1994-04-11 AU AU65667/94A patent/AU6566794A/en not_active Abandoned
- 1994-04-11 US US08/557,187 patent/US5691379A/en not_active Expired - Fee Related
- 1994-04-11 EP EP94913566A patent/EP0697863A1/de not_active Withdrawn
- 1994-04-11 CA CA002162467A patent/CA2162467A1/en not_active Abandoned
- 1994-04-13 TW TW083103295A patent/TW265264B/zh active
- 1994-05-20 IL IL10970194A patent/IL109701A0/xx unknown
- 1994-05-20 ZA ZA943514A patent/ZA943514B/xx unknown
- 1994-05-20 PH PH48312A patent/PH31652A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE4345199A1 (de) | 1994-12-01 |
| AU6566794A (en) | 1994-12-20 |
| JPH08511246A (ja) | 1996-11-26 |
| IL109701A0 (en) | 1994-08-26 |
| CA2162467A1 (en) | 1994-12-08 |
| US5691379A (en) | 1997-11-25 |
| PH31652A (en) | 1999-01-12 |
| WO1994027592A1 (de) | 1994-12-08 |
| EP0697863A1 (de) | 1996-02-28 |
| TW265264B (cs) | 1995-12-11 |
| DE4345199C2 (de) | 1995-10-12 |
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