ZA943353B - 2-aminopyrazine-5-carboxamide derivatives their preparation and their application in therapeutics - Google Patents

2-aminopyrazine-5-carboxamide derivatives their preparation and their application in therapeutics

Info

Publication number
ZA943353B
ZA943353B ZA943353A ZA943353A ZA943353B ZA 943353 B ZA943353 B ZA 943353B ZA 943353 A ZA943353 A ZA 943353A ZA 943353 A ZA943353 A ZA 943353A ZA 943353 B ZA943353 B ZA 943353B
Authority
ZA
South Africa
Prior art keywords
group
hydrogen atom
optionally substituted
aminopyrazine
therapeutics
Prior art date
Application number
ZA943353A
Other languages
English (en)
Inventor
Pascal George
Benoit Marabout
Jacques Froissant
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of ZA943353B publication Critical patent/ZA943353B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA943353A 1993-05-17 1994-05-16 2-aminopyrazine-5-carboxamide derivatives their preparation and their application in therapeutics ZA943353B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9305930A FR2705344B1 (fr) 1993-05-17 1993-05-17 Dérivés de 2-aminopyrazine-5-carboxamide, leur préparation et leur application en thérapeutique.

Publications (1)

Publication Number Publication Date
ZA943353B true ZA943353B (en) 1995-03-28

Family

ID=9447217

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA943353A ZA943353B (en) 1993-05-17 1994-05-16 2-aminopyrazine-5-carboxamide derivatives their preparation and their application in therapeutics

Country Status (19)

Country Link
US (1) US5420130A (xx)
EP (1) EP0625514B1 (xx)
JP (1) JPH06329645A (xx)
CN (1) CN1104637A (xx)
AT (1) ATE183742T1 (xx)
AU (1) AU671361B2 (xx)
CA (1) CA2123668A1 (xx)
CZ (1) CZ283499B6 (xx)
DE (1) DE69420179D1 (xx)
FI (1) FI942265A (xx)
FR (1) FR2705344B1 (xx)
HU (1) HUT69711A (xx)
IL (1) IL109655A (xx)
NO (1) NO941830L (xx)
NZ (1) NZ260531A (xx)
PL (1) PL173309B1 (xx)
RU (1) RU2128176C1 (xx)
SK (1) SK57494A3 (xx)
ZA (1) ZA943353B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA00010805A (es) * 1998-05-06 2002-05-08 Univ Duke Metodo para el tratamiento de sindromes de la vejiga y del tracto urinario inferior.
PL200955B1 (pl) 1998-08-20 2009-02-27 Toyama Chemical Co Ltd Przeciwwirusowa kompozycja farmaceutyczna i jej zastosowanie oraz zawierająca azot heterocykliczna pochodna karboksamidu

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4041032A (en) * 1974-01-16 1977-08-09 Yamanouchi Pharmaceutical Co., Ltd. Pyrazine derivatives
FR2656609B1 (fr) * 1989-12-28 1992-03-27 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
CN1104637A (zh) 1995-07-05
FR2705344A1 (fr) 1994-11-25
CA2123668A1 (en) 1994-11-18
SK57494A3 (en) 1995-07-11
AU671361B2 (en) 1996-08-22
EP0625514B1 (fr) 1999-08-25
EP0625514A1 (fr) 1994-11-23
PL173309B1 (pl) 1998-02-27
DE69420179D1 (de) 1999-09-30
FR2705344B1 (fr) 1995-06-30
CZ283499B6 (cs) 1998-04-15
RU94016363A (ru) 1996-04-10
ATE183742T1 (de) 1999-09-15
NZ260531A (en) 1995-10-26
FI942265A (fi) 1994-11-18
JPH06329645A (ja) 1994-11-29
HU9401512D0 (en) 1994-08-29
IL109655A0 (en) 1994-08-26
CZ119594A3 (en) 1994-12-15
AU6312694A (en) 1994-11-24
FI942265A0 (fi) 1994-05-16
RU2128176C1 (ru) 1999-03-27
US5420130A (en) 1995-05-30
NO941830D0 (no) 1994-05-16
IL109655A (en) 1999-03-12
NO941830L (no) 1994-11-18
HUT69711A (en) 1995-09-28

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